(Q28083049)

language of work or name

1 reference

September 2015

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Basic and Clinical Pharmacology and Toxicology

published in

1 reference

volume

117

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1 reference

147-55

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Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood.

cites work

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

The unique characteristics of the placental transcriptome and the hormonal metabolism enzymes in placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Placental transfer and metabolism: an overview of the experimental models utilizing human placental tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Drug metabolism in alcoholics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Environmental factors of enzyme induction and inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Diabetes and elimination of antipyrine in man: an analysis of 298 patients classified by type of diabetes, age, sex, duration of disease and liver involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Hepatocytes: the powerhouse of biotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Effects of microsomal enzyme inducers in vivo and inhibitors in vitro on the covalent binding of benzo[a]pyrene metabolites to DNA catalyzed by liver microsomes from genetically responsive and nonresponsive mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Pyrazole is different from acetone and ethanol as an inducer of the polysubstrate monooxygenase system in mice: evidence that pyrazole-inducible P450Coh is distinct from acetone-inducible P450ac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Comparison between cobalt and pyrazole in the increased expression of coumarin 7-hydroxylase in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Polymorphisms of CYP2A6 and its practical consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Metabolism of bilirubin by human cytochrome P450 2A6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Cimetidine inhibits microsomal drug metabolism in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Cimetidine: interaction with oral anticoagulants in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Liquid chromatography-mass spectrometry in in vitro drug metabolite screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Human placental xenobiotic and steroid biotransformations catalyzed by cytochrome P450, epoxide hydrolase, and glutathione S-transferase activities and their relationships to maternal cigarette smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Expression and localization of CYP3A4 and CYP3A5 in human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Cytochrome P4502A5 expression and inducibility by phenobarbital is modulated by cAMP in mouse primary hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Regulation of CYP 2 A 5 induction by porphyrinogenic agents in mouse primary hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Metabolism of ophthalmic timolol: new aspects of an old drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

In vitro prediction of gastrointestinal absorption and bioavailability: an experts' meeting report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

In silico prediction of ADME and pharmacokinetics. Report of an expert meeting organised by COST B15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Prediction of drug metabolism and interactions on the basis of in vitro investigations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Effects of pharmaceuticals and other active chemicals at biological targets: mechanisms, interactions, and integration into PB-PK/PD models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

From known knowns to known unknowns: predicting in vivo drug metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

In vivo-in vitro-in silico pharmacokinetic modelling in drug development: current status and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Reactive metabolites in early drug development: predictive in vitro tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Ospemifene metabolism in humans in vitro and in vivo: metabolite identification, quantitation, and CYP assignment of major hydroxylations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Effects of ospemifene on drug metabolism mediated by cytochrome P450 enzymes in humans in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Analytical challenges for conducting rapid metabolism characterization for QIVIVE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Biotransformation in vitro: An essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Characterization of human cytochrome P450 induction by pesticides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Comparative metabolism of benfuracarb in in vitro mammalian hepatic microsomes model and its implications for chemical risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Energy-sensing factors coactivator peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Metformin induces PGC-1α expression and selectively affects hepatic PGC-1α functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Omics and its potential impact on R&D and regulation of complex herbal products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Cytochrome P450 isoforms in human fetal tissues related to phenobarbital-inducible forms in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Microarray Analysis of the Global Alterations in the Gene Expression in the Placentas From Cigarette-smoking Mothers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

Preservation, induction or incorporation of metabolism into the in vitro cellular system − Views to current opportunities and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FBCPT.12429

release_mvnlbqevkrch5gcr6fzai6v3wy

21 January 2018

Identifiers

DOI

10.1111/BCPT.12429

0 references

Fatcat ID

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PubMed publication ID

26073298

1 reference