(Q41584700)

English

New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis

scientific article published on 26 February 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis (English)

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

quantitative structure-activity relationship

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

author name string

L E Korhonen

1

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

M Rahnasto

3

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

C Wittekindt

4

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

O Pelkonen

6

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

H Raunio

7

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

R O Juvonen

8

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

language of work or name

0 references

publication date

26 February 2007

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

150

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

932-942

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

In vitro screening of drug metabolism during drug development: can we trust the predictions?

1 reference

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6 June 2018

Cytochrome p450 in silico: an integrative modeling approach.

1 reference

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6 June 2018

Predicting drug-drug interactions in drug discovery: where are we now and where are we going?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Inhibition by ticlopidine and its derivatives of human liver cytochrome p450. Mechanism-based inactivation of CYP 2C19 by ticlopidine.

1 reference

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6 June 2018

Mechanism-based inactivators as probes of cytochrome P450 structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2-phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Monospecific antipeptide antibody to cytochrome P-450 2B6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Further characterization of the expression in liver and catalytic activity of CYP2B6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Characterization of cytochrome P-450 2B6 in human liver microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

6 June 2018

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Potent Mechanism-Based Inhibition of Human CYP2B6 by Clopidogrel and Ticlopidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Combined three-dimensional quantitative structure-activity relationship analysis of cytochrome P450 2B6 substrates and protein homology modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2013880

19 August 2018

Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17325652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics: towards the prediction of human p450 substrate specificity and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17325652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional quantitative structure activity relationship analyses of substrates for CYP2B6

1 reference

https://pubmed.ncbi.nlm.nih.gov/17325652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17325652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/17325652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0707173

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 October 2017

ResearchGate publication ID

0 references

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