Philadelphia International Airport is a major international hub for American Airlines and a regional cargo hub for UPS Airlines, as well as a focus city for Frontier Airlines. Recently American has named PHL is "crown jewel" and added flights to Budapest, Des Moines, Madison, Omaha, Prague, San Antonio, and Zurich.
OneJet is a commuter airline based in Pittsburgh, which announced a new base in Milwaukee, starting flights to Omaha and Columbus, as well as an existing flight to Pittsburgh. The airline plans to add up to 10 new routes to MKE in the next 6 months, as well as open a new base in one of their currently served cities. As of October 2017, OneJet serves Albany, Cincinnati, Columbus, Hartford, Indianapolis, Louisville, Milwaukee, Nashville, Omaha, Pittsburgh, Providence, and Richmond.