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KIF25

From Wikipedia, the free encyclopedia
KIF25
Identifiers
AliasesKIF25, KNSL3, kinesin family member 25
External IDsOMIM: 603815; HomoloGene: 49939; GeneCards: KIF25; OMA:KIF25 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005355
NM_030615

n/a

RefSeq (protein)

NP_005346
NP_085118

n/a

Location (UCSC)Chr 6: 168 – 168.05 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Kinesin family member 25 (KIF25), also known as kinesin-14, is a human protein encoded by the KIF25 gene. It is part of the kinesin family of motor proteins.

Function

[edit]

KIF25 is a minus-end directed microtubule motor protein, and its activity delays the separation of chromosomes during mitosis.[3]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125337Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Decarreau J, Wagenbach M, Lynch E, Halpern AR, Vaughan JC, Kollman J, Wordeman L (April 2017). "The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation". Nature Cell Biology. 19 (4): 384–390. doi:10.1038/ncb3486. PMC 5376238. PMID 28263957.