40S ribosomal protein S17

RPS17
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5A2Q, 5AJ0, 4UJE, 4D5L, 4UJD, 5FLX, 4D61, 4UJC
Identifiers
Aliases	RPS17, DBA4, RPS17L, RPS17L1, RPS17L2, S17, ribosomal protein S17
External IDs	OMIM: 180472; MGI: 1309526; HomoloGene: 110867; GeneCards: RPS17; OMA:RPS17 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	82,540,459 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	80,995,002 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; corpus callosum; ; left ovary; ; ventricular zone; ; right ovary; ; skin of abdomen; ; skin of leg; ; lymph node; ; Achilles tendon; ; right uterine tube;
	Top expressed in
	embryo; ; ventricular zone; ; embryo; ; morula; ; lip; ; blastocyst; ; yolk sac; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of ribosome; RNA binding;
Cellular component	cytosol; ribosome; membrane; focal adhesion; intracellular anatomical structure; cytosolic small ribosomal subunit; extracellular exosome; nucleoplasm; extracellular matrix; synapse;
Biological process	viral transcription; SRP-dependent cotranslational protein targeting to membrane; erythrocyte homeostasis; translational initiation; ribosomal small subunit assembly; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit biogenesis; protein biosynthesis; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	6218
	20068
	ENSG00000278229; ENSG00000182774
	ENSMUSG00000061787
	P08708
	P63276
	NM_001021; NM_001199057
	NM_009092
	NP_001012
	NP_033118
	Wikidata
View/Edit Human	View/Edit Mouse

40S ribosomal protein S17 is a protein that in humans is encoded by the RPS17 gene.^[5]^[6]^[7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[7]

References

^ ^a ^b ^c ENSG00000182774 GRCh38: Ensembl release 89: ENSG00000278229, ENSG00000182774 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061787 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics. 13 (1): 201–7. doi:10.1016/0888-7543(92)90221-D. PMID 1577483.
^ Filipenko ML, Iantsen EI, Muravlev AI, Kopantsev EP, Karpova GG, Mertvetsov NP (Oct 1995). "[Mapping the genes for ribosomal proteins S14 and S17 on human chromosomes using cDNA from a panel of hybrid cells]". Bioorg Khim. 21 (5): 349–53. PMID 7661859.
^ ^a ^b "Entrez Gene: RPS17 ribosomal protein S17".

External links

GeneReviews/NCBI/NIH/UW entry on Diamond-Blackfan Anemia

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[refGRCh38Ensembl-1] ENSG00000182774 GRCh38: Ensembl release 89: ENSG00000278229, ENSG00000182774 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000061787 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1577483-5] Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics. 13 (1): 201–7. doi:10.1016/0888-7543(92)90221-D. PMID 1577483.

[pmid7661859-6] Filipenko ML, Iantsen EI, Muravlev AI, Kopantsev EP, Karpova GG, Mertvetsov NP (Oct 1995). "[Mapping the genes for ribosomal proteins S14 and S17 on human chromosomes using cDNA from a panel of hybrid cells]". Bioorg Khim. 21 (5): 349–53. PMID 7661859.

[entrez-7] "Entrez Gene: RPS17 ribosomal protein S17".

[1]

References

Further reading

External links