Jump to content

16S rRNA (cytosine1407-C5)-methyltransferase

From Wikipedia, the free encyclopedia
16S rRNA (cytosine1407-C5)-methyltransferase
Identifiers
EC no.2.1.1.178
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

16S rRNA (cytosine1407-C5)-methyltransferase (EC 2.1.1.178, RNA m5C methyltransferase YebU, RsmF, YebU) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytosine1407-C5)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytosine1407 in 16S rRNA S-adenosyl-L-homocysteine + 5-methylcytosine1407 in 16S rRNA

The enzyme specifically methylates cytosine1407 at C5 in 16S rRNA.

References

[edit]
  1. ^ Andersen NM, Douthwaite S (June 2006). "YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407". Journal of Molecular Biology. 359 (3): 777–86. doi:10.1016/j.jmb.2006.04.007. PMID 16678201.
  2. ^ Hallberg BM, Ericsson UB, Johnson KA, Andersen NM, Douthwaite S, Nordlund P, Beuscher AE, Erlandsen H (July 2006). "The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain". Journal of Molecular Biology. 360 (4): 774–87. doi:10.1016/j.jmb.2006.05.047. PMID 16793063.
[edit]