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Talk:Kawasaki disease

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Former good article nomineeKawasaki disease was a Natural sciences good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake.
Article milestones
DateProcessResult
June 6, 2010Good article nomineeNot listed

Previous discussions without headers

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Latest comment: 14 years ago4 comments4 people in discussion

Is anyone able to add a pathology section? The disease is explained and discussed but the underlying mechanism isn't mentioned.

The Treatment is repeated in the Prognosis. Suggest removing the final line from the prognosis section. Kilbosh 14:24, 4 April 2006 (UTC)Reply

I clarified the prevalence of coronary artery aneurysms. Can someone show me how to reference the source? It is in Pediatr Infect Dis J. 2006 Mar;25(3):245-9. Pkoetters 05:48, 10 August 2006 (UTC)Reply

  • Two aspects here - firstly if the item is a footnote (i.e. to verify or expand on a specific fact within the article, vs source for the whole article which would be a reference) need place it into a footnote section with forward and back links to relevant location in the text. There are several methods for this, latest being metawiki's cite.php system and described at WP:Footnotes that encloses a citation within <ref> details </ref> tags up in the text (and <references/> in the Footnotes section to list out the items)
    Hence at relevant point in text (after punctuation) insert:
    <ref>Author Title Pediatr Infect Dis J. 2006 Mar;25(3):245-9</ref>
  • Secondly is how to format the citation details themselves. Other than also needing authors and a title, this can be left as plain text as above, manually formated with single-quotes used to italicise the journal ''this'' = this, or bold the issue number '''that''' = that. Alternatively there are various citation templates to format and structure details for you, in this example we need a journal citation so see Template:cite journal.
    Hence: {{cite journal | author=AUTHOR | title=TITLE | journal=Pediatr Infect Dis J | year=2006 | month=Mar | volume=25 | issue=3 | pages=245-9 }}
    Gives: AUTHOR (2006). "TITLE". Pediatr Infect Dis J. 25 (3): 245–9. {{cite journal}}: Unknown parameter |month= ignored (help)
  • So to combine footnotes and citation templates: <ref>{{cite journal | ...... }}</ref> and under Footnotes section header rememember to have a <references/>
  • Finally if you can locate on PubMed the article's abstract number, add an additional id=PMID ####### parameter to create a link to it, e.g. PMID 123456. Very useful for all of this is Diberri's tool (http://diberri.dyndns.org/wikipedia/templates/) that takes a PubMed abstract number and autogenerates the cite journal template markup which can then be copied & pasted into wikipedia, e.g. see this example.

John Travolta's son had this disease and just died?

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Latest comment: 13 years ago5 comments5 people in discussion

If I read this wiki entry correctly, only 2% of children die from this.

I'm wondering if in fact Jett died from this , did the fact that his parents are Scientologists (don't adhere to some modern medical treatments) have anything to do with his death. In other words, was he getting proper treatment? —Preceding unsigned comment added by 65.184.76.241 (talk) 21:53, 2 January 2009 (UTC)Reply

Sorry this is now irrelevant, updated article explained that the death was due to a head injury sustained during a seizure.
I removed that section/sentence because he died from head injuries, not from the disease. NeoDeGenero (talk) 04:17, 3 January 2009 (UTC)Reply

The page may need protection, or a blurb about the boy's death to be left up for, say, a week?sinneed (talk)

Jett Travolta son of John Travolta is hardly "famous", and is probably not even notable. It is certainly not clear that he died from Kawasaki Syndrome. Perhaps this section should be renamed, or deleted? AussieBoy (talk) 06:17, 4 January 2009 (UTC)Reply

Can Kawasaki disease cause seizures? F W Nietzsche (talk) 09:04, 6 January 2009 (UTC) theoretically,KD (kawasaki disease),could cause febrile seizures,as persistant high fever is a hallmark of KD.However,jett had the disease at age 2,and the only known long term sequalae from KD is cardiovascular,so there is no reason to think that jett's death is in any way related to KD.Regards.Immunize (talk) 21:34, 17 January 2010 (UTC)Reply

Yes, seizures are seen during the disease, but long-term effects or sequelae has not been determined. Children with Kawasaki syndrome do not continue to have seizures after the disease has resolved. Seizures are likely related to Jett's autism, as many parents of autistic children have noted he had autism. —Preceding unsigned comment added by 64.126.65.190 (talk) 03:35, 21 February 2011 (UTC)Reply

Teachable moment

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Latest comment: 15 years ago1 comment1 person in discussion

Now that Kawasaki disease is in the news, this page will get a lot of hits. It attracts vandalism, but it's also a teachable moment to educate people about Kawasaki disease.

It's a good educational opportunity, because autoimmune diseases, and specifically vasculitis, is a large class of important diseases with high incidence. Nbauman (talk) 06:24, 6 January 2009 (UTC)Reply

Update for 'Causes' section

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Latest comment: 15 years ago1 comment1 person in discussion

A recent international study has identified new genes that appear to affect susceptibility to Kawasaki disease. The study found that genes involved in cardiovascular function and inflammation may be particularly important and some seem to function together.

Reference: The article is in PLoS Genetics, an open-access journal, and is freely available online at http://www.plosgenetics.org/doi/pgen.1000319. Citation: Burgner D, Davila S, Breunis WB, Ng SB, Li Y, et al. (2009) A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease. PLoS Genet 5(1): e1000319. doi:10.1371/journal.pgen.1000319 PMID: 19132087 Plosgenetics (talk) 16:18, 13 January 2009 (UTC)Reply

refs 3 and 4

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Latest comment: 15 years ago1 comment1 person in discussion

Whoever is working on this article - check refs 3 and 4 in the Presentation section - I removed some vandalism, but the refs themselves appeared to be valid sources for Kawasaki disease. I'm just not sure where you want to use them. — Ched ~ (yes?)/© 06:58, 15 March 2009 (UTC)Reply

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Latest comment: 14 years ago5 comments2 people in discussion

I categorized this under Category:Virus-related cutaneous conditions under the rational from section Pathogenesis chapter 80:1232-4 from Dermatology Second edition from Bolognia, Jean L. ISBN 1-4160-2999-0. [1] Calmer Waters 20:25, 24 December 2009 (UTC)Reply

Sounds great! ---kilbad (talk) 20:28, 24 December 2009 (UTC)Reply
However, its already under Vascular cutaneous conditions Calmer Waters 20:37, 24 December 2009 (UTC)Reply
You can do both if you want. Your call... ---kilbad (talk) 20:38, 24 December 2009 (UTC)Reply
Uggh. That one was killing me. Spent the last hour trying to pin it down only to find out it was already in one. Two it is. Thanks Calmer Waters 20:44, 24 December 2009 (UTC)Reply

GA Review

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Latest comment: 14 years ago44 comments4 people in discussion
This review is transcluded from Talk:Kawasaki disease/GA1. The edit link for this section can be used to add comments to the review.

Reviewer: Rcej (Robert) - talk 04:36, 1 April 2010 (UTC)Reply

Hello :) We'll begin the review in a couple days or so... I need to read thru closely and prepare, etc., first. Rcej (Robert) - talk 04:36, 1 April 2010 (UTC)Reply

Thank you for your efforts, and I ll be working with you on this :-) MaenK.A.Talk 10:46, 1 April 2010 (UTC)Reply

I think we can start now :) I like to focus on just a few issues at a time, so things don't seem overwhelming; I also like the nominator to set the pace of the review. Since you or whomever helps (if) will be doing the work, feel free to take as much time as you choose... and holler when you're ready! No hurry, ever :)

Now, about the article; we are definitely getting it to GA... but we have a lot of stuff to do. You've done some good work generally defining the disease; now we'll go deeper! So, first up:

  • The article is under-cited and under-referenced. Every sentence and list item must be cited, the exception being that several sentences/list items/a paragraph is verifiably covered by a source. If the latter is the case, one citation at the end of the paragraph or list is fine :) Also, we need to increase the number of journal sources; but as the article grows, that'll happen naturally. We must not have any 'citation needed' stickers, either.
  • The first section should be a Classification section. Where does Kawasaki disease fit in alongside other inflammatory autoimmune diseases affecting the cutaneous tissue and mucosa associated with the lymphatic system? How is KD delineated from other such diseases? Classification should address things like that. Here's an example of a GA Classification section.

Well, that's enough stuff to worry about until you are ready to move on. Absolutely, tell me/ask me whatever you are concerned with or need :) And always, take whatever time you need! Rcej (Robert) - talk 08:16, 2 April 2010 (UTC)Reply

  • First thank you for giving me the chance to chose the pace, and that is exactly what I want, since as you know I am a medical student and I am busy studying most of the time, I am currently working on this, which is a list of resources I will use to improve the article, I don't want to disrupt the article over a long period, so I started collecting them under a subpage, And I ll inform you when I am done. Thank you again MaenK.A.Talk 13:42, 2 April 2010 (UTC)Reply
Well hello aren't you prepared :) Cool subpage! Rcej (Robert) - talk 01:51, 3 April 2010 (UTC)Reply
thank you :-), and I am sorry for that, its just that I ve just had a big pediatrics exam, and I was too busy to get things ready before you did the review MaenK.A.Talk 07:45, 3 April 2010 (UTC)Reply
No need to apologize :) I've done the exact same thing during a very tedious review where I was the nominator. I became a subpageaholic! I had the page deleted once I didn't need it. Rcej (Robert) - talk 08:22, 3 April 2010 (UTC)Reply
How about this as a start for the classification section, I want to develop it under a subpage before moving to article MaenK.A.Talk 17:25, 6 April 2010 (UTC)Reply
Great start! One thing to keep in mind when writing medicine articles especially, is to use as neutral of syntax as possible; for instance where you have "...preferably coronary arteries.", you might want to weaken that slightly to read something like "...often including coronary arteries." :) Rcej (Robert) - talk 04:05, 7 April 2010 (UTC)Reply
Shall I use multiple citations for the same statement like you did here?? MaenK.A.Talk 17:39, 6 April 2010 (UTC)Reply
The reason I do that sometimes is because the entire statement could only be supported by all of those particular sources collectively, and since I don't like to ref within a sentence... I just pile them up after the end of the sentence. That's a very acceptable referencing style too, and much neater looking :) Makes for easier rewrites, also! Rcej (Robert) - talk 04:05, 7 April 2010 (UTC)Reply
Great, I am currently adding multiple references to the article you may need to check that MaenK.A.Talk 17:27, 7 April 2010 (UTC)Reply
Nice! But don't worry about wikilinking the journal titles... unecessary, a hassle, and some persnickity medical wiki-ers actually frown on it :) Rcej (Robert) - talk 03:35, 8 April 2010 (UTC)Reply
Thank you for the advise about the linking of the journal titles, are we done with the classification section now?? MaenK.A.Talk 16:31, 9 April 2010 (UTC)Reply
Not ready yet :) Let's flesh out two areas: 1. What finding(s) in KD within the designation 'systemic vasculitis' delineates it from others of that designation? Specify the findings and the other disorders (PMID 18524103). 2. Is KD typically known to affect medium-sized vasculature? (PMID 19946711) Clarify, and mention other disorders in this area too. Rcej (Robert) - talk 03:55, 10 April 2010 (UTC)Reply
Is it Done now :-) MaenK.A.Talk 13:45, 10 April 2010 (UTC)Reply
Nope. Gotta go for now, tho... we'll resume shortly :) Rcej (Robert) - talk 08:41, 12 April 2010 (UTC)Reply

Ok...I'm back :) Here's what the Classification section needs now:

Yes, you are right... that's best left for pathophysiology. Rcej (Robert) - talk 04:59, 26 April 2010 (UTC)Reply
  • "It is a syndrome affecting multiple organ systems, and in the acute stage of KD, systemic inflammatory changes are evident in many organs." Describe the inflammatory changes.

This seems tedious... and it is, actually. But we need in this section to establish the identity of KD among its 'peers', as much as possible. Rcej (Robert) - talk 03:53, 13 April 2010 (UTC)Reply

What now?? are we done with that?? MaenK.A.Talk 22:37, 25 April 2010 (UTC)Reply
Not yet :) We need to know where in the classification scheme of systemic vasculitis KD fits, specifying that KD is a medium sized arterial vasculitis and what criteria in systemic vasculitis determines the designation 'medium sized'. Also, KD is a primary childhood vasculitis. How does primary childhood vasculitis relate to 'medium sized' and systemic vasculitis? Here's two new sources, one has a link to a full text ver: PMID 18761873, PMID 16322081; also, you may want to revisit two you're already using, PMID 19946711, PMID 17408915. Seems like a lot still, but we'll be ready to move on eventually ;D Rcej (Robert) - talk 04:59, 26 April 2010 (UTC)Reply
You know I cant exactly know what you want me to do, can you please help with completing the section?? I mean I cant find a way to state "what criteria in systemic vasculitis determines the designation 'medium sized'" or "How does primary childhood vasculitis relate to 'medium sized' and systemic vasculitis" even though I red the two resources you provide and many more!!,sorry for that. more than that, I believe that the section is ok now and if you check any Kawasaki review you will not find a wider classification section, that is if you find that section which is rarely referred to, and actually this is making the process harder MaenK.A.Talk 16:48, 27 April 2010 (UTC)Reply
I will finish up the section ASAP :) hmm... give me a couple days to figure out what we need to focus on next! Rcej (Robert) - talk 07:08, 29 April 2010 (UTC)Reply
That would be great, thank you, and take your time :-) MaenK.A.Talk 18:17, 29 April 2010 (UTC)Reply

Tables

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Please check the tables at the diagnosis and the symptoms sections, and give me an opinion MaenK.A.Talk 14:28, 16 April 2010 (UTC)Reply

The table 'less common manifestations' is nice! The ref used for the 'Criteria for diagnosis' table is a book; cite the page numbers too :) I would rather not have a 'Differential diagnosis' table; we will likely require a Differential diagnosis subsection in Diagnosis. That would have to tell us how the diagnosis of KD is reached when another specified disorder is suspected. Rcej (Robert) - talk 06:37, 17 April 2010 (UTC)Reply
I have removed the Differential diagnosis table MaenK.A.Talk 15:57, 17 April 2010 (UTC)Reply

See also

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This content should usually be combined into the article.Doc James (talk · contribs · email) 17:50, 2 May 2010 (UTC)Reply

True; but as the current article is not the final version, and I'm attempting to conduct the review in a specifically ordered fashion... we are not going to incorporate that list yet, when things are apt to change :) Rcej (Robert) - talk 03:41, 3 May 2010 (UTC)Reply

Update: almost done with classification; I may have done a poor job explaining this type section... I can 'do' slightly better than I can 'tell', apparently ;) Two new things for you to do:

Good job! Rcej (Robert) - talk 05:43, 10 May 2010 (UTC)Reply
  •   Done


Also, let's not cut/paste text from a source; if this applies to you, make it a habit of writing all of your additions to any wiki article completely in your own words. Good practice, too, for the further you go in your medical career :) If you want to impress the hardcore, persnickity professors/doctors that are void of human emotions... writing proficiently in all areas will do it every time! Rcej (Robert) - talk 06:02, 4 May 2010 (UTC)Reply

Next: in the Signs and symptoms section; the bullet list of common symptoms is basically a repetition of the paragraph above, albeit more specific. Let's incorporate that listing into the paragraph, and the less common symptoms in that table could instead be a bullet list below the paragraph.-- Rcej (Robert) - talk 05:43, 10 May 2010 (UTC)Reply

I am so sorry this is taking so long, but I am very busy now with my final exams, but I will be available soon MaenK.A.Talk 17:36, 17 May 2010 (UTC)Reply
No worries :) Much success with your finals! Rcej (Robert) - talk 06:28, 18 May 2010 (UTC)Reply
So what is happening? GA reviews should really take only a week or two. –– Jezhotwells (talk) 01:23, 6 June 2010 (UTC)Reply
The nominator has some personal matters that have come up, so I'm allowing him some extra time. Some reviews take months... are you subjugating this one? :) Rcej (Robert) - talk 01:49, 6 June 2010 (UTC)Reply
I understand that, but the general consensus at WT:GAN is one or two weeks. Articles can always be renominated and the review process shpuld not be a long drawn out process. –– Jezhotwells (talk) 02:04, 6 June 2010 (UTC)Reply
I was kind of going by the looser time consensus here, but I'll try to speed things up. :) Rcej (Robert) - talk 04:12, 6 June 2010 (UTC)Reply

Picture query (picture G)

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Latest comment: 14 years ago4 comments2 people in discussion

On the grid of pictures picture G doesn't look like any way of giving BCG that I've seen (could be a Heaf test I suppose). 3x3 grids of needle pricks look like some form of a skin prick (allergy) test to me. Looks like it came from a journal but doesn't necesarily mean the right caption or correct picture made it into the article. Going to be awkward to photoshop it out though. Arfgab (talk) 14:07, 13 April 2010 (UTC)Reply

You are right, I took the picture and the caption from the same article that I am citing. I think that this mistake was published in the paper too, if it is a mistake in the first place. But as you said, I ve never seen a smiler BCG vaccination, so what do you think should be done here?? MaenK.A.Talk 15:08, 13 April 2010 (UTC)Reply
I guess the only thing would be to e-mail the author for clarification. It is Korean and I've never worked there so they may do things differently. Arfgab (talk) 19:59, 13 April 2010 (UTC)Reply
Not sure why there are 2 grids on this picture but take a look at the picture around Bacillus_Calmette-Guérin#Method of administration and see if you think that looks familiar. (Apologies to Dr Kim) Arfgab (talk) 20:03, 13 April 2010 (UTC)Reply

File:KAWASAKI1.jpg Nominated for Deletion

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Latest comment: 13 years ago1 comment1 person in discussion
  An image used in this article, File:KAWASAKI1.jpg, has been nominated for deletion at Wikimedia Commons in the following category: Deletion requests July 2011
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A discussion will now take place over on Commons about whether to remove the file. If you feel the deletion can be contested then please do so (commons:COM:SPEEDY has further information). Otherwise consider finding a replacement image before deletion occurs.

This notification is provided by a Bot --CommonsNotificationBot (talk) 02:05, 12 July 2011 (UTC)Reply

Overall, about 2% of patients die from complications of coronary vasculitis

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Latest comment: 11 years ago1 comment1 person in discussion

This line is misleading for the prognosis of kawasaki disease. Though this disease is a type of coronary vasculitis, coronary vasculitis isn't exclusively kawasaki disease. If it is meant to be representative of kawasaki disease then the 2% quoted is most likely a SMR, or standard mortality ratio, that quantifies an increase in mortality relative to the general population. For instance, in "Sudden Death in an Infant Revealing Atypical Kawasaki Disease" the mortality rate caused by KD is 2.8% higher than the general population. [2] The Merck Manual quotes 0.17% mortality rate with adequate therapy in the United States. 

 — Preceding unsigned comment added by Kimqcat (talk • contribs) 04:09, 1 July 2013 (UTC)Reply

Causes

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Latest comment: 11 years ago1 comment1 person in discussion

The article as it is now states that we should call it Kawasaki Syndrome, in the causes section. The reasons given for this are that the cause is not known. However, immediately after this statement, the article resumes calling it Kawasaki Disease. Is this an issue, and if so, is there a way to correct it? — Preceding unsigned comment added by 174.20.189.191 (talk) 15:02, 18 October 2013 (UTC)Reply

Structure in "Signs & Symptoms"

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Latest comment: 8 years ago1 comment1 person in discussion

The first couple of sentences here could be reworded to be clearer. Also the wiki link from "remittent" goes to the article "Fever". I made an attempt at fixing the latter and then realised I'd misinterpreted the sentence. Will try to remember to revisit but writing here in case I don't. Dichohecho (talk) 12:15, 15 September 2016 (UTC)Reply

Scientific statement

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Latest comment: 7 years ago1 comment1 person in discussion

doi:10.1161/CIR.0000000000000484 JFW | T@lk 08:28, 25 April 2017 (UTC)Reply

A Commons file used on this page or its Wikidata item has been nominated for deletion

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Latest comment: 4 years ago1 comment1 person in discussion

The following Wikimedia Commons file used on this page or its Wikidata item has been nominated for deletion:

Participate in the deletion discussion at the nomination page. —Community Tech bot (talk) 13:22, 3 May 2020 (UTC)Reply

Definition

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Latest comment: 4 years ago6 comments2 people in discussion

@Doc James: This is the definition provided at the start of the main text of the current AHA guidelines: [1]

Kawasaki disease (KD) is an acute, self-limited febrile illness of unknown cause that predominantly affects children <5 years of age.

I believe we need to go with something along those lines at the start of the lead that highlight the paediatric context – especially for the benefit of casual readers, including ones coming rapidly to this page following current newspaper reports regarding unusual COVID manifestations in some infants. 86.134.212.26 (talk) 14:09, 8 May 2020 (UTC)Reply

Adding: The definition in our frequently used PubMed Health source [2] also immediately highlights the paediatric context:

Kawasaki (KAH-wah-SAH-ke) disease is a rare childhood disease. It's a form of a condition called vasculitis...

86.134.212.26 (talk) 15:33, 8 May 2020 (UTC)Reply

Okay simplified a bit to "is a disease of unknown cause that results in a fever and mainly affects children under 5 years of age" thoughts? Doc James (talk · contribs · email) 02:23, 9 May 2020 (UTC)Reply
@Doc James: Ok, though I believe the clear-cut 'vasculitis' definition (per PubMed Health [3]) also needs to be close to the top, as it was before (rather than trailing speculation regarding the mechanism). Will switch that one back [4]. 86.134.212.26 (talk) 12:15, 9 May 2020 (UTC)Reply
Sure, moved some of the less common symptoms out of the lead. Doc James (talk · contribs · email) 08:16, 10 May 2020 (UTC)Reply
Agree, and looking good, imo :-) 86.134.212.26 (talk) 09:54, 10 May 2020 (UTC)Reply

COVID-19

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Latest comment: 4 years ago2 comments1 person in discussion

At present we have a summary at the foot of == History == of the ongoing open questions regarding Kawasaki-like presentations. Imo, that's appropriate, whereas (per WP:RECENT, whereas news-style (local/global) updates would not be on this page about a particular clinical entity (example). Clearly, per WP:MEDRS, it would be premature to insert speculative/primary-sourced content in clinical sections (e.g. == Causes ==). A little like User:KalanK10 (I think) however, I have been wondering whether some brief mention of the issue should be made at the foot of the lead, as that might be what general readers would expect. Personally, I feel something of the sort [5] may be appropriate. 86.134.212.26 (talk) 10:28, 10 May 2020 (UTC)Reply

(Reflist)

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  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 2201. ISBN 1-4160-2999-0. {{cite book}}: |access-date= requires |url= (help)CS1 maint: multiple names: authors list (link)
  2. ^ Diana MC, Villa G, Gattorno M, Ottonello G, Costabel S, Savioli C, DiPietro P. 2006. Sudden Death in an Infant Revealing Atypical Kawasaki Disease. Ped Emerg Care. 22(1):35-37.

Signs and symptoms

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Under this section there are pictures of symptoms, but they are not stated except by a letter. Can someone more knowledgeable than I am please label these symptoms by the letter in order to clarify the symptom pictured.

Moving here

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Latest comment: 4 years ago2 comments2 people in discussion
This article is about Kawasaki disease. For for the novel illnesses similar to the Kawasaki disease that has been observed in children possibly linked with COVID-19, see Paediatric multisystem inflammatory syndrome.

We mention PMIS both in the infobox under differential and in the second paragraph. We do not also need a banner at the top of the article.

Doc James (talk · contribs · email) 05:55, 14 May 2020 (UTC)Reply

DocJames Didn't see it in the infobox, apologies. Was hoping the hat note would spur editors to update the PIMS page instead of this one and a few others. If you get a chance could you give the multisystem inflammatory syndrome disambiguation a look over to see if it is clear enough? Best, Classicwiki (talk) If you reply here, please ping me. 16:33, 14 May 2020 (UTC)Reply

moved content

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Latest comment: 4 years ago2 comments1 person in discussion

@User:Doricke: The content added here is sourced to a (possibly still not peer-reviewed) hypothesis-type paper which does not comply with WP:MEDRS:

A novel hypothesis that Kawasaki disease is caused by dysregulated activation of mast cells by Fc receptor-bound pathogen antibodies accounts for much of the pathology of this disease[1]. Histamine release from mast cells induces contraction of pericyte or effector cells on cardiac capillaries impeding blood flow[1]. Back pressure from capilaries occulsions induces coronary aneurysms in some patients[1]. Other Kawasaki disease symptoms can be linked to increased histamine levels.

  1. ^ a b c "Kawasaki Disease, Multisystem Inflammatory Syndrome in Children: Antibody-Induced Mast Cell Activation Hypothesis" (PDF). MIT Lincoln Laboraotry. 11 June 2020 (PDF). {{cite web}}: Check |archiveurl= value (help)

86.186.155.159 (talk) 08:44, 12 June 2020 (UTC)Reply

moved content

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From diff (apparently following on from earlier addition of analagous content by Doricke, a SPA whose user name virtually coincides with that of the first author of this hypothesis-type paper):

The hypothesis has been put forward that Kawasaki Disease is caused by antibody activation of mast cells.[1]

  1. ^ Ricke DO, Gherlone N, Fremont-Smith P, Tisdall P, Fremont-Smith M (2020). "Kawasaki Disease, Multisystem Inflammatory Syndrome in Children: Antibody-Induced Mast Cell Activation Hypothesis". J Pediatrics & Pediatr Med. 4 (2): 1–7.

86.186.155.159 (talk) 08:38, 24 July 2020 (UTC)Reply

Some current MEDRS

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Latest comment: 4 years ago1 comment1 person in discussion

(some *selected* recent potential medrs etc, as of June 2020; not all actually cited):

Guidelines / Consensus statements:

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  • "Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease (JCS 2013). Digest version". Circulation Journal: Official Journal of the Japanese Circulation Society. 78 (10): 2521–62. 2014. doi:10.1253/circj.cj-66-0096. PMID 25241888. [current]

Books

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  • Jameson, TL; Fauci, AS; Kasper, DL (2017). Harrison's Principles of Internal Medicine 19th Edition and Harrison's Manual of Medicine 19th Edition. McGraw-Hill Education. ISBN 978-1-260-12907-6. [no open-access]

Reviews

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General

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Diagnosis and clinical management

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Systematic reviews / meta-analysis
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Other
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Research:

Causes, pathogenesis, epidemiology, etc

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  • Lo MS (2020). "A framework for understanding Kawasaki disease pathogenesis". Clinical Immunology (Orlando, Fla.). 214: 108385. doi:10.1016/j.clim.2020.108385. PMID 32173601.
    <ref name=Lo2020/> *Not* open-access
  • Onouchi Y (2018). "The genetics of Kawasaki disease". International Journal of Rheumatic Diseases. 21 (1): 26–30. doi:10.1111/1756-185X.13218. PMID 29152908.
    <ref name=Onouchi2018/> *Not* open-access

Role of immunization

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  • Phuong LK, Bonetto C, Buttery J, et al. (2016). "Kawasaki disease and immunisation: Standardised case definition & guidelines for data collection, analysis". Vaccine. 34 (51): 6582–6596. doi:10.1016/j.vaccine.2016.09.025. PMID 27863715.

Recent SCIRS for History

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86.186.155.159 (talk) 12:24, 15 June 2020 (UTC)Reply

Add topic
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