KCR may refer to:
- K. Chengalaraya Reddy, first Chief Minister of the former Indian state of Mysore
- K. Chandrashekar Rao, the first and former Chief Minister of the Indian state of Telangana
- Kansas City Royals, a Major League Baseball team
- Karachi Circular Railway, the proposed metro rail system of Karachi, Pakistan
- Kienning Colloquial Romanized, a romanization system adopted by Western missionaries to compile the Kienning dialect (modern day Jian'ou City) of the Northern Min language in the Fujian Province of China
- KCR, a landmark crossroads in Dublin, Ireland
- KCR CRO, Contract Research Organization
- KCR (SDSU), a student-run radio station at San Diego State University in San Diego, California, United States
- Kowloon–Canton Railway (disambiguation)