FBL

FBL
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2IPX
Dynodwyr
Cyfenwau	FBL, FIB, FLRN, RNU3IP1, fibrillarin, Nop1
Dynodwyr allanol	OMIM: 134795 HomoloGene: 1099 GeneCards: FBL
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0102674, GO:0102675 methyltransferase activity • transferase activity • rRNA methyltransferase activity • ATPase binding • histone-glutamine methyltransferase activity • GO:0001948, GO:0016582 protein binding • TFIID-class transcription factor complex binding • RNA binding Cydrannau o'r gell • small-subunit processome • Cajal body • bilen • nucleolus • dense fibrillar component • extracellular exosome • cnewyllyn cell • box C/D RNP complex • granular component • Cromosom • nucleoplasm • fibrillar center Prosesau biolegol • tRNA processing • snoRNA localization • rRNA methylation • histone glutamine methylation • methylation • box C/D RNA 3'-end processing • sno(s)RNA metabolic process • osteoblast differentiation • rRNA processing Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2091	n/a
Ensembl	ENSG00000105202 ENSG00000280548	n/a
UniProt	P22087	n/a
RefSeq (mRNA)	NM_001436	n/a
RefSeq (protein)	NP_001427	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FBL yw FBL a elwir hefyd yn rRNA 2'-O-methyltransferase fibrillarin a Fibrillarin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19q13.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FBL.

• "Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions. ". Biochemistry (Mosc). 2016. PMID 27682166.
• "Fibrillarin, a nucleolar protein, is required for normal nuclear morphology and cellular growth in HeLa cells. ". Biochem Biophys Res Commun. 2007. PMID 17603021.
• "Proteasome-dependent processing of nuclear proteins is correlated with their subnuclear localization. ". J Struct Biol. 2002. PMID 12490167.
• "U3 snoRNP associates with fibrillarin a component of the scleroderma clumpy nucleolar domain. ". Arch Dermatol Res. 2002. PMID 12373336.
• "Systemic sclerosis (scleroderma): specific autoantigen genes are selectively overexpressed in scleroderma fibroblasts.". J Immunol. 2001. PMID 11739535.