File:Erythropoietin-Protects-Cardiomyocytes-from-Cell-Death-during-HypoxiaReperfusion-Injury-through-pone.0107453.s002.ogv
Erythropoietin-Protects-Cardiomyocytes-from-Cell-Death-during-HypoxiaReperfusion-Injury-through-pone.0107453.s002.ogv (Ogg Theora video file, length 46 s, 512 × 512 pixels, 105 kbps, file size: 592 KB)
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[edit]DescriptionErythropoietin-Protects-Cardiomyocytes-from-Cell-Death-during-HypoxiaReperfusion-Injury-through-pone.0107453.s002.ogv |
English: After 8 hrs of hypoxia cells were visualized under confocal microscope and live cell images were taken in time series mode of about 0.2 secs for 15 min. Hypoxia medium were replaced by fresh DMEM + 10% FBS to reoxygenate those cells and live cell images were taken for 15 mins of reperfusion. After 8 hrs of hypoxia exposure, Ca2+ accumulates more in the mitochondria and the nucleus compared to the cytosol. At the start of reperfusion MPTP open and the mitochondrial membrane ruptures due to a Ca2+influx into the mitochondria. |
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Source | Video S2 from Parvin A A, A R, U S, Devendran A, Baker J, Dhanasekaran A (2014). "Erythropoietin Protects Cardiomyocytes from Cell Death during Hypoxia/Reperfusion Injury through Activation of Survival Signaling Pathways". PLOS ONE. DOI:10.1371/journal.pone.0107453. PMID 25474199. PMC: 4169563. | |||
Author | Parvin A A, A R, U S, Devendran A, Baker J, Dhanasekaran A | |||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 22:53, 10 December 2014 | 46 s, 512 × 512 (592 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Parvin A A, A R, U S, Devendran A, Baker J, Dhanasekaran A |
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Usage terms | http://creativecommons.org/publicdomain/zero/1.0/ |
Image title | After 8 hrs of hypoxia cells were visualized under confocal microscope and live cell images were taken in time series mode of about 0.2 secs for 15 min. Hypoxia medium were replaced by fresh DMEM + 10% FBS to reoxygenate those cells and live cell images were taken for 15 mins of reperfusion. After 8 hrs of hypoxia exposure, Ca2+ accumulates more in the mitochondria and the nucleus compared to the cytosol. At the start of reperfusion MPTP open and the mitochondrial membrane ruptures due to a Ca2+influx into the mitochondria. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014 |