S Wikipedije, slobodne enciklopedije
Mali prolinom bogati protein 2A jest protein koji je kod ljudi kodiran genom SPRR2A sa hromosoma 1 .[ 5] [ 6]
Dužina polipeptidnog lanca je 72 aminokiseline , a molekulska težina 7.965 Da .[ 7]
10 20 30 40 50 MSYQQQQCKQ PCQPPPVCPT PKCPEPCPPP KCPEPCPPPK CPQPCPPQQC QQKYPPVTPS PPCQSKYPPK SK
^ a b c GRCh38: Ensembl release 89: ENSG00000241794 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046259 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (Aug 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins". Genomics . 16 (3): 630–7. doi :10.1006/geno.1993.1240 . PMID 8325635 . ^ "Entrez Gene: SPRR2A small proline-rich protein 2A" .^ "UniProt, P35326" (jezik: engleski). Pristupljeno 19. 12. 2021 .
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1" . Nature . 441 (7091): 315–21. Bibcode :2006Natur.441..315G . doi :10.1038/nature04727 PMID 16710414 . Tong L, Corrales RM, Chen Z, et al. (2006). "Expression and Regulation of Cornified Envelope Proteins in Human Corneal Epithelium" . Invest. Ophthalmol. Vis. Sci . 47 (5): 1938–46. doi :10.1167/iovs.05-1129 . PMC 2906387 PMID 16639001 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Hong SH, Nah HY, Lee JY, et al. (2004). "Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus". Mol. Cells . 17 (3): 477–84. PMID 15232223 . Cabral A, Fischer DF, Vermeij WP, Backendorf C (2003). "Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation" . J. Biol. Chem . 278 (20): 17792–9. doi :10.1074/jbc.M300508200 PMID 12624109 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags" . Proc. Natl. Acad. Sci. U.S.A . 97 (7): 3491–6. Bibcode :2000PNAS...97.3491D . doi :10.1073/pnas.97.7.3491 PMC 16267 PMID 10737800 . Fischer DF, van Drunen CM, Winkler GS, et al. (1999). "Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker" . Nucleic Acids Res . 26 (23): 5288–94. doi :10.1093/nar/26.23.5288 . PMC 147987 PMID 9826750 . Steinert PM, Marekov LN (1997). "Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope" . J. Biol. Chem . 272 (3): 2021–30. doi :10.1074/jbc.272.3.2021 PMID 8999895 . Fischer DF, Gibbs S, van De Putte P, Backendorf C (1996). "Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation" . Mol. Cell. Biol . 16 (10): 5365–74. doi :10.1128/MCB.16.10.5365 . PMC 231535 PMID 8816448 . Gibbs S, Lohman F, Teubel W, et al. (1990). "Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes" . Nucleic Acids Res . 18 (15): 4401–7. doi :10.1093/nar/18.15.4401 . PMC 331257 PMID 2388825 .
