About: Pranlukast

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Pranlukast (brand name Onon, オノン) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s montelukast (Singulair). It is widely used in Japan. Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

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dbo:abstract
  • Pranlukast (brand name Onon, オノン) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s montelukast (Singulair). It is widely used in Japan. Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens. Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective. Pranlukast is also reported as potential inhibitor of Mycobacterium tuberculosis infection in experimental models. (en)
  • Pranlukast (nella fase sperimentale conosciuto anche con la sigla ONO 1078) è un farmaco antiasmatico con attività antagonista sui recettori per i leucotrieni. Il farmaco, appartenente alla stessa classe di montelukast e zafirlukast, è ampiamente utilizzato in Giappone. (it)
  • プランルカスト(Pranlukast、開発コード:ONO 1078)はロイコトリエン阻害薬の一つであり、システイニル-ロイコトリエンの受容体結合を阻害して抗喘息作用および抗鼻炎作用を示す。商品名オノン。 (ja)
  • Pranlukast (łac. pranlukastum) – wielofunkcyjny organiczny związek chemiczny, lek przeciwleukotrienowy, stosowany w leczeniu astmy oskrzelowej oraz alergicznego nieżytu nosa (kataru siennego), wprowadzony na rynek farmaceutyczny jedynie w Japonii. (pl)
dbo:alternativeName
  • Onon (オノン) (en)
dbo:casNumber
  • 103177-37-3
dbo:chEMBL
  • 21333
dbo:drugbank
  • DB01411
dbo:fdaUniiCode
  • TB8Z891092
dbo:pubchem
  • 4887
dbo:thumbnail
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  • 4800832 (xsd:integer)
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  • 4054 (xsd:nonNegativeInteger)
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  • 979871464 (xsd:integer)
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dbp:atcPrefix
  • R03 (en)
dbp:atcSuffix
  • DC02 (en)
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  • 27 (xsd:integer)
dbp:casNumber
  • 103177 (xsd:integer)
dbp:chembl
  • 21333 (xsd:integer)
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  • 4718 (xsd:integer)
dbp:drugbank
  • DB01411 (en)
dbp:eliminationHalfLife
  • 5400.0 (dbd:second)
dbp:h
  • 23 (xsd:integer)
dbp:iupacName
  • N-[4-oxo-2--4H-chromen-8-yl]-4-benzamide (en)
dbp:iupharLigand
  • 3634 (xsd:integer)
dbp:metabolism
  • Hepatic (en)
dbp:n
  • 5 (xsd:integer)
dbp:o
  • 4 (xsd:integer)
dbp:pubchem
  • 4887 (xsd:integer)
dbp:routesOfAdministration
  • Oral (en)
dbp:smiles
  • O=Cc5ccccc5 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • NBQKINXMPLXUET-UHFFFAOYSA-N (en)
dbp:tradename
  • Onon (en)
dbp:unii
  • TB8Z891092 (en)
dbp:verifiedrevid
  • 464213227 (xsd:integer)
dbp:watchedfields
  • changed (en)
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dct:subject
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rdfs:comment
  • Pranlukast (nella fase sperimentale conosciuto anche con la sigla ONO 1078) è un farmaco antiasmatico con attività antagonista sui recettori per i leucotrieni. Il farmaco, appartenente alla stessa classe di montelukast e zafirlukast, è ampiamente utilizzato in Giappone. (it)
  • プランルカスト(Pranlukast、開発コード:ONO 1078)はロイコトリエン阻害薬の一つであり、システイニル-ロイコトリエンの受容体結合を阻害して抗喘息作用および抗鼻炎作用を示す。商品名オノン。 (ja)
  • Pranlukast (łac. pranlukastum) – wielofunkcyjny organiczny związek chemiczny, lek przeciwleukotrienowy, stosowany w leczeniu astmy oskrzelowej oraz alergicznego nieżytu nosa (kataru siennego), wprowadzony na rynek farmaceutyczny jedynie w Japonii. (pl)
  • Pranlukast (brand name Onon, オノン) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s montelukast (Singulair). It is widely used in Japan. Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens. (en)
rdfs:label
  • Pranlukast (it)
  • プランルカスト (ja)
  • Pranlukast (en)
  • Pranlukast (pl)
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