About: ETS transcription factor family

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In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six. (Erythroblast Transformation Specific)) family is one of the largest families of transcription factors and is unique to animals. There are 29 genes in humans, 28 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila. The founding member of this family was identified as a gene transduced by the leukemia virus, E26. The members of the family have been implicated in the development of different tissues as well as cancer progression.

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  • In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six. (Erythroblast Transformation Specific)) family is one of the largest families of transcription factors and is unique to animals. There are 29 genes in humans, 28 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila. The founding member of this family was identified as a gene transduced by the leukemia virus, E26. The members of the family have been implicated in the development of different tissues as well as cancer progression. (en)
  • ETS (bahasa Inggris: E26 transformation-specific) adalah sekelompok faktor transkripsi yang mengatur diferensiasi, respon terhadap hormon dan lintasan pada sejumlah organ endokrin dan jaringan tubuh. Ets-1, salah satu anggota ETS, merupakan protein yang langsung mengatur banyak gen penting pada lintasan angiogenesis dan extracellular matrix remodeling, seperti MMP-1, MMP-3, MMP-9, , dan . MAPK merupakan enzim akan mengaktivasi Ets-1 dan Ets-2. (in)
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  • Ets
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  • 16790755 (xsd:integer)
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  • 10109 (xsd:nonNegativeInteger)
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  • 1103532462 (xsd:integer)
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  • Structure of Ets-1 DNA binding autoinhibition. (en)
dbp:interpro
  • IPR000418 (en)
dbp:name
  • Ets-domain (en)
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  • , , , , , , , , , , , , , , , , , , , (en)
dbp:pfam
  • PF00178 (en)
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  • CL0123 (en)
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  • PDOC00374 (en)
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  • 1 (xsd:integer)
dbp:smart
  • SM00413 (en)
dbp:symbol
  • Ets (en)
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  • In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six. (Erythroblast Transformation Specific)) family is one of the largest families of transcription factors and is unique to animals. There are 29 genes in humans, 28 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila. The founding member of this family was identified as a gene transduced by the leukemia virus, E26. The members of the family have been implicated in the development of different tissues as well as cancer progression. (en)
  • ETS (bahasa Inggris: E26 transformation-specific) adalah sekelompok faktor transkripsi yang mengatur diferensiasi, respon terhadap hormon dan lintasan pada sejumlah organ endokrin dan jaringan tubuh. Ets-1, salah satu anggota ETS, merupakan protein yang langsung mengatur banyak gen penting pada lintasan angiogenesis dan extracellular matrix remodeling, seperti MMP-1, MMP-3, MMP-9, , dan . MAPK merupakan enzim akan mengaktivasi Ets-1 dan Ets-2. (in)
rdfs:label
  • ETS transcription factor family (en)
  • ETS (in)
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