Summary: Metal lattice structures filled with a damping material such as polymer can exhibit high stiffness and good damping properties. Mechanical simulations of parts made from these composites can however require a large modeling and computational effort because relevant features such as complex geometries need to be represented on multiple scales. The finite cell method (FCM) and numerical homogenization are potential remedies for this problem. Moreover, if the microstructures are placed in between the components of assemblies for vibration reduction, a modified mortar technique can further increase the efficiency of the complete simulation process. With this method, it is possible to discretize the components separately and to integrate the viscoelastic behavior of the composite damping layer into their weak coupling. This paper provides a multiscale computational material design framework for such layers, based on FCM and the modified mortar technique. Its efficiency even in the case of complex microstructures is demonstrated in numerical studies. Therein, computational homogenization is first performed on various microstructures before the resulting effective material parameters are used in larger-scale simulation models to investigate their effect and to verify the employed methods.