Summary: The paper continues the development of the multiple 1D-embedding-based (or, 1D multi-embedding) methods for semi-supervised learning, which is preliminarily introduced by the author [ibid. 14, No. 2, Article ID 1640002, 11 p. (2016; Zbl 1333.68236)]. This paper puts the development in a more general framework and creates a new method, which employs the ensemble technique to integrate multiple 1D embedding-based regularization and label boosting for semi-supervised learning (SSL). It combines parallel ensemble and serial ensemble. In each stage of parallel ensemble, the dataset is first smoothly mapped onto multiple 1D sequences. On each 1D embedded data, a classical regularization method is applied to construct a weak classifier. All of these weak classifiers are then integrated to an ensemble of 1D labeler (E1DL), which together with a nearest neighbor cluster (NNC) algorithm extracts a newborn labeled subset from the unlabeled set. The subset is believed to be correctly labeled with a high confidence, so that it joins with the original labeled set for the next learning stage. Repeating this process, we gradually obtain a boosted labeled set and the process will not stopped until the updated labeled set reaches a certain size. Finally, we use E1DL to build the target classifier, which labels all points of the dataset. In this paper, we also set the universal parameters for all experiments to make the algorithm as a parameter-free one. The validity of our method in the classification of the handwritten digits is confirmed by several experiments. Comparing to several other popular SSL methods, our results are very promising.