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Asymmetric type II compound Laplace distribution and its application to microarray gene expression. (English) Zbl 1243.62017

Summary: The asymmetric type II compound Laplace distribution is introduced and various properties are studied. The maximum likelihood estimation procedure is employed to estimate the parameters of the proposed distribution and an algorithm in the R package is developed to carry out the estimation. Simulation studies for various choices of parameter values are performed to validate the algorithm. Finally, we fit the asymmetric type II compound Laplace, asymmetric Laplace, and log-normal distributions to five microarray gene expression dataets and compare them.

MSC:

62E10 Characterization and structure theory of statistical distributions
62F10 Point estimation
62P10 Applications of statistics to biology and medical sciences; meta analysis
92C40 Biochemistry, molecular biology
65C60 Computational problems in statistics (MSC2010)

Software:

R; marrayClasses
Full Text: DOI

References:

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