×

Stochastic simulation of HIV population dynamics through complex network modelling. (English) Zbl 1142.92029

Summary: We propose a new way to model HIV infection spreading through the use of dynamic complex networks. The heterogeneous population of HIV exposure groups is described through a unique network degree probability distribution. The time evolution of the network nodes is modelled by a Markov process and gives insight in HIV disease progression. The results are validated against historical data of AIDS cases in the USA as recorded by the Center of Disease Control. We find a remarkably good correspondence between the number of simulated and registered HIV cases, indicating that our approach to modelling the dynamics of HIV spreading through a sexual network is a valid approach that opens up completely new ways of reasoning about various medication scenarios.

MSC:

92C60 Medical epidemiology
65C20 Probabilistic models, generic numerical methods in probability and statistics
94C99 Circuits, networks
Full Text: DOI

References:

[1] DOI: 10.1097/00002030-199901140-00014 · doi:10.1097/00002030-199901140-00014
[2] DOI: 10.1002/(SICI)1097-0258(19971015)16:19<2191::AID-SIM645>3.0.CO;2-5 · doi:10.1002/(SICI)1097-0258(19971015)16:19<2191::AID-SIM645>3.0.CO;2-5
[3] Anderson R. M., Infectious Diseases in Humans (1992)
[4] DOI: 10.1016/0025-5564(88)90079-X · Zbl 0673.92008 · doi:10.1016/0025-5564(88)90079-X
[5] Arni S. R., Math. Biosci. Eng 2 pp 263– (2005) · Zbl 1071.62108 · doi:10.3934/mbe.2005.2.263
[6] Bai W. J., Interplay between HIV/AIDS epidemics and demographic structures based on sexual contact networks (2007) · Zbl 1137.92027
[7] Bartlett J. G., Routine opt-out testing for HIV: rationale and obstacles (2007)
[8] DOI: 10.1080/10273660600890057 · Zbl 1111.92025 · doi:10.1080/10273660600890057
[9] Batagelj V., Connections 21 pp 47– (1998)
[10] Benoit J., Eur. Phys. J 50 pp 177– (2006) · doi:10.1140/epjb/e2006-00096-x
[11] Boccara, N. 2004.Modeling Complex Systems, 410Springer. · Zbl 1072.37059
[12] DOI: 10.2307/2288844 · Zbl 0644.62108 · doi:10.2307/2288844
[13] DOI: 10.1016/S0378-4371(03)00429-1 · Zbl 1026.92038 · doi:10.1016/S0378-4371(03)00429-1
[14] HIV/AIDS database at Centers for Disease Control and Prevention (CDC) Available athttp://www.cdc.gov/hiv/
[15] HIV/AIDS Surveillance in Europe. End-year Report 2003 No. 70 (2003)
[16] DOI: 10.1016/S0025-5564(02)00128-1 · Zbl 1037.92033 · doi:10.1016/S0025-5564(02)00128-1
[17] Kindermann W., Addiction 11 pp 1372– (1984)
[18] DOI: 10.1038/35082140 · doi:10.1038/35082140
[19] Longini I. M., J. Acquir. Immune Defic. Syndr 4 pp 1141– (1991)
[20] DOI: 10.1016/S1201-9712(00)90105-X · doi:10.1016/S1201-9712(00)90105-X
[21] DOI: 10.1097/00002030-199902250-00001 · doi:10.1097/00002030-199902250-00001
[22] DOI: 10.1177/003754979807100402 · doi:10.1177/003754979807100402
[23] DOI: 10.1103/PhysRevLett.86.3200 · doi:10.1103/PhysRevLett.86.3200
[24] DOI: 10.1103/PhysRevE.65.036104 · doi:10.1103/PhysRevE.65.036104
[25] DOI: 10.1097/00002030-200205030-00021 · doi:10.1097/00002030-200205030-00021
[26] DOI: 10.1097/00002030-200401020-00010 · doi:10.1097/00002030-200401020-00010
[27] 2006 Report on the global AIDS epidemic, UNAIDS/WHO, 2006
[28] Schneeberger A., Sex Transm. Dis 6 pp 380– (2004) · doi:10.1097/00007435-200406000-00012
[29] DOI: 10.1007/s10877-005-0673-2 · doi:10.1007/s10877-005-0673-2
[30] Sloot, P. M.A., Chen, F. and Boucher, C. A. 2002.Cellular automata model of drug therapy for HIV infectionVol. 2493, 282–293.Lecture Notes in Computer Science · Zbl 1027.92504
[31] Sloot P. M.A., IEEE Comput 39 pp 40– (2006) · doi:10.1109/MC.2006.380
[32] DOI: 10.1016/j.bulm.2004.10.004 · Zbl 1334.92240 · doi:10.1016/j.bulm.2004.10.004
[33] DOI: 10.1002/sim.2432 · doi:10.1002/sim.2432
[34] United Nations, Population Division, Department of Economic and Social Affairs. World Population Prospects: The 2004 Revision, 2005
[35] Yang R., Phys. Lett. A: Gen. At. Solid State Phys 364 pp 189– (2007)
This reference list is based on information provided by the publisher or from digital mathematics libraries. Its items are heuristically matched to zbMATH identifiers and may contain data conversion errors. In some cases that data have been complemented/enhanced by data from zbMATH Open. This attempts to reflect the references listed in the original paper as accurately as possible without claiming completeness or a perfect matching.