Blood flow velocity in the choroid in punctate inner choroidopathy and Vogt-Koyanagi-Harada disease; and multifractal analysis of choroidal blood flow in age-related macular degeneration. (English) Zbl 1131.92034
Yakubo, Kousuke (ed.) et al., Topological aspects of critical systems and networks. Proceedings of the international symposium, Saporo, Japan, February 13–14, 2006. With CD-ROM. Hackensack, NJ: World Scientific (ISBN 978-981-270-736-9/hbk). 106-113 (2007).
Summary: Recently, the important role of the choroidal circulation has been recognized in various fundus diseases, such as punctate inner choroidopathy (PIC), Vogt-Koyanagi-Harada (VKH) disease, and age-related macular degeneration (AMD). An apparatus based on the laser speckle phenomenon, which we call laser speckle flowgraphy (LSFG), has been used to measure the blood flow velocity in the retina and choroid with the diode laser. PI is present in myopic women who complain of decreased visual acuity. The VKH disease is a bilateral, granulomatous chorioretinitis. The composite map of the LSFG represents that blood flow velocity in the choroid was decreased in PIC and VKH. After the treatment, blood flow velocity in this area was increased in both disease and visual acuity recovered.
LSFG appears to be a safe and sensitive means to evaluate disease progression and response to therapy. A multifractal analysis has been performed for blood flow data in the composite map of the LSFG. In consequence, multifractality becomes clearly worse for the AMD patient compared to normal choroidal blood flows. The multifractal analysis of LSFG data represents an additional useful method to detect the early stage of AMD.
For the entire collection see [Zbl 1119.82004].
LSFG appears to be a safe and sensitive means to evaluate disease progression and response to therapy. A multifractal analysis has been performed for blood flow data in the composite map of the LSFG. In consequence, multifractality becomes clearly worse for the AMD patient compared to normal choroidal blood flows. The multifractal analysis of LSFG data represents an additional useful method to detect the early stage of AMD.
For the entire collection see [Zbl 1119.82004].
