Mechanisms and consequences of activation of protein kinase B/Akt (Q41751003)

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scientific article published on April 1998

Language	Label	Description	Also known as
English	Mechanisms and consequences of activation of protein kinase B/Akt	scientific article published on April 1998

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

1 reference

Europe PubMed Central

Mechanisms and consequences of activation of protein kinase B/Akt (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

Julian Downward

1

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

publication date

1 April 1998

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

Current Opinion in Cell Biology

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

262-267

1 reference

Europe PubMed Central

PubMed publication ID

8 October 2017

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning of a second form of rac protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

GSK3: a SHAGGY frog story

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 3-dependent survival by the Akt protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980149-X

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1016/S0955-0674(98)80149-X

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30 July 2022

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release_7eqvneusjfchhl5mdjq44de7w4

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https://api.fatcat.wiki/v0/release/7eqvneusjfchhl5mdjq44de7w4

30 July 2022

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PubMed publication ID

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30 July 2022

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