Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment (Q39503772)

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Language	Label	Description	Also known as
English	Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Howard L. Kaufman

5

object named as

Howard L Kaufman

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

author name string

Seunghee Kim-Schulze

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Hong Sung Kim

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Qing Fan

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Dae Won Kim

4

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

publication date

25 November 2008

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Europe PubMed Central

PMC publication ID

12 September 2017

Molecular Therapy

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Europe PubMed Central

PMC publication ID

12 September 2017

17

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

380-388

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta

1 reference

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Stromal gene expression predicts clinical outcome in breast cancer

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IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

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IL-21 mediated Foxp3 suppression leads to enhanced generation of antigen-specific CD8+ cytotoxic T lymphocytes

1 reference

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

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Regulatory T cells, transforming growth factor-beta, and immune suppression

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The tumour microenvironment and implications for cancer immunotherapy

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TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

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Regulatory T cells under scrutiny

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1 reference

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Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034262

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based on heuristic

inferred from PubMed ID database lookup

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034262

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based on heuristic

inferred from PubMed ID database lookup

A new approach to the therapy of cancer based on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034262

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based on heuristic

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Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034262

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inferred from PubMed ID database lookup

A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19034262

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IL-21 enhances SOCS gene expression and inhibits LPS-induced cytokine production in human monocyte-derived dendritic cells

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https://pubmed.ncbi.nlm.nih.gov/19034262

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Identifiers

10.1038/MT.2008.249

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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