Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity (Q30923970)

From Wikidata

Jump to navigation Jump to search

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

scientific article

Language	Label	Description	Also known as
English	Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

directed evolution

0 references

1 reference

based on heuristic

inferred from title

author name string

E T Boder

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

K S Midelfort

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

K D Wittrup

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

1 September 2000

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

97

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

20

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

10701-10705

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Optimal screening of surface-displayed polypeptide libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Selection for improved protein stability by phage display.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Pharmacokinetics and biodistribution of genetically-engineered antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Probing the importance of second sphere residues in an esterolytic antibody by phage display

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Antibody affinity maturation using bacterial surface display.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Anatomy of an antibody molecule: structure, kinetics, thermodynamics and mutational studies of the antilysozyme antibody D1.3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Antigen specificity and tumour targeting efficiency of a human carcinoembryonic antigen-specific scFv and affinity-matured derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Isolation of anti-T cell receptor scFv mutants by yeast surface display

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Yeast surface display for screening combinatorial polypeptide libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Structural insights into the evolution of an antibody combining site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

T cell receptor biochemistry, repertoire selection and general features of TCR and Ig structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

In vitro scanning saturation mutagenesis of an antibody binding pocket

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

1.85 A structure of anti-fluorescein 4-4-20 Fab

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Mutational analysis of active site contact residues in anti-fluorescein monoclonal antibody 4-4-20.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Rapid evolution of a protein in vitro by DNA shuffling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Kinetic and affinity limits on antibodies produced during immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

High resolution structures of the 4–4-20 Fab-fluorescein complex in two solvent systems: effects of solvent on structure and antigen-binding affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

4-4-20 anti-fluorescyl IgG Fab' recognition of membrane bound hapten: direct evidence for the role of protein and interfacial structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Thermodynamic properties of ligand binding by monoclonal anti-fluorescyl antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Single-step purification of shuttle vectors from yeast for high frequency back-transformation into E. coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. Relative contributions of VH and VL genes, minigenes, and complementarity-determining regions to binding of antibody-combining sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Assembly of IgH CDR3: Mechanism, Regulation, and Influence on Antibody Diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

21 June 2018

Fine affinity discrimination by yeast surface display and flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

25 November 2018

Improving in vivo folding and stability of a single-chain Fv antibody fragment by loop grafting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

25 November 2018

The role of antibody concentration and avidity in antiviral protection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

25 November 2018

Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

25 November 2018

Mechanisms of ligand binding by monoclonal anti-fluorescyl antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=27086

25 November 2018

Protection from lethal coronavirus infection by immunoglobulin fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular dynamics of the anti-fluorescein 4-4-20 antigen-binding fragment. 2. Time-resolved fluorescence spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular dynamics of the anti-fluorescein 4-4-20 antigen-binding fragment. 1. Computer simulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation rate constant of the biotin-streptavidin complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody framework residues affecting the conformation of the hypervariable loops

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of electrostatic interactions in the binding of fluorescein by anti-fluorescein antibody 4-4-20

1 reference

https://pubmed.ncbi.nlm.nih.gov/10984501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.170297297

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

2000PNAS...9710701B

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q30923970&oldid=1549151442"