tRNA as an active chemical scaffold for diverse chemical transformations (Q28741217)

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scientific article (publication date: 21 January 2010)

Language	Label	Description	Also known as
English	tRNA as an active chemical scaffold for diverse chemical transformations	scientific article (publication date: 21 January 2010)

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scholarly article

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Europe PubMed Central

tRNA as an active chemical scaffold for diverse chemical transformations (English)

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structural biology

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author name string

Christopher S Francklyn

1

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Anand Minajigi

2

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language of work or name

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publication date

21 January 2010

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584

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2

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366-75

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RNA-assisted catalysis in a protein enzyme: The 2'-hydroxyl of tRNA(Thr) A76 promotes aminoacylation by threonyl-tRNA synthetase

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Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei

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17 March 2017

Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation

1 reference

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Structure and catalytic mechanism of eukaryotic selenocysteine synthase

1 reference

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Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase

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17 March 2017

Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus

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1 reference

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1 reference

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Biosynthesis of selenocysteine on its tRNA in eukaryotes

1 reference

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RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea

1 reference

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Structure and functions of the GNAT superfamily of acetyltransferases

1 reference

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17 March 2017

Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

Crystal structures of Weissella viridescens FemX and its complex with UDP-MurNAc-pentapeptide: insights into FemABX family substrates recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

On protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

X-ray crystal structure of Staphylococcus aureus FemA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

pH-dependent conformational flexibility within the ribosomal peptidyl transferase center.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

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The N-end rule: functions, mysteries, uses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

17 March 2017

Coenzymes as fossils of an earlier metabolic state

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

7 April 2017

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Identification, characterization, and bioconversion of a new intermediate in valanimycin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

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Asymmetric amino acid activation by class II histidyl-tRNA synthetase from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Isolation, crystallization and preliminary X-ray analysis of the transamidosome, a ribonucleoprotein involved in asparagine formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Investigations of valanimycin biosynthesis: elucidation of the role of seryl-tRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Dynamics of Recognition between tRNA and elongation factor Tu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

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RNA-dependent lipid remodeling by bacterial multiple peptide resistance factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Cytoplasmic steps of peptidoglycan biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

From one amino acid to another: tRNA-dependent amino acid biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Idiosyncratic features in tRNAs participating in bacterial cell wall synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The ribosomal peptidyl transferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Regulation of a glutamyl-tRNA synthetase by the heme status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Kinetic discrimination of tRNA identity by the conserved motif 2 loop of a class II aminoacyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

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Mechanism of tRNA-dependent editing in translational quality control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Molecular mechanisms of bacterial resistance to antimicrobial peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Participation of the tRNA A76 hydroxyl groups throughout translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The ribosome as an entropy trap

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

BIOSYNTHESIS OF CELL WALL MUCOPEPTIDE BY A PARTICULATE FRACTION FROM STAPHYLOCOCCUS AUREUS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Escherichia coli glutamyl-tRNA reductase. Trapping the thioester intermediate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Cysteinyl-tRNA synthetase is not essential for viability of the archaeon Methanococcus maripaludis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Ribozyme-catalyzed tRNA aminoacylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Cysteinyl-tRNA formation: the last puzzle of aminoacyl-tRNA synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Methanopyrus kandleri glutamyl-tRNA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The essential Staphylococcus aureus gene fmhB is involved in the first step of peptidoglycan pentaglycine interpeptide formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Specificities of FemA and FemB for different glycine residues: FemB cannot substitute for FemA in staphylococcal peptidoglycan pentaglycine side chain formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The participation of sRNA in the enzymatic synthesis of O-L-lysyl phosphatidylgylcerol in Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Incorporation of glycine into the cell wall glycopeptide in Staphylococcus aureus: role of sRNA and lipid intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Transfer RNA as a cofactor coupling amino acid synthesis with that of protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Biosynthesis of the peptidoglycan of bacterial cell walls. X. Further study of the glycyl transfer ribonucleic acids active in peptidoglycan synthesis in Staphylococcus aureus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The Biosynthesis of the Cross-linking Peptides in the Cell Wall Peptidoglycan of Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Biosynthesis of the peptidoglycan of bacterial cell walls. IX. Purification and properties of glycyl transfer ribonucleic acid synthetase from Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The RNA required in the first step of chlorophyll biosynthesis is a chloroplast glutamate tRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Selenocysteine synthase from Escherichia coli. Analysis of the reaction sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

The N-end rule in bacteria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Unusual resistance of peptidyl transferase to protein extraction procedures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Hydrolytic action of aminoacyl-tRNA synthetases from baker's yeast: "chemical proofreading" preventing acylation of tRNA(I1e) with misactivated valine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Transfer RNA: Molecular Structure, Sequence, and Properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241936

3 June 2018

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reaction

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Substrate-assisted catalysis of peptide bond formation by the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Plasticity of recognition of the 3'-end of mischarged tRNA by class I aminoacyl-tRNA synthetases

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

The transamidosome: a dynamic ribonucleoprotein particle dedicated to prokaryotic tRNA-dependent asparagine biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

RNA-dependent cysteine biosynthesis in archaea

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Aminoacylation of tRNA with phosphoserine for synthesis of cysteinyl-tRNA(Cys).

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Synthesis of mosaic peptidoglycan cross-bridges by hybrid peptidoglycan assembly pathways in gram-positive bacteria

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Kinetic and mechanistic characterization of recombinant Lactobacillus viridescens FemX (UDP-N-acetylmuramoyl pentapeptide-lysine N6-alanyltransferase).

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Aminoacyl-tRNA recognition by the FemXWv transferase for bacterial cell wall synthesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Adaptation of Pseudomonas aeruginosa to various conditions includes tRNA-dependent formation of alanyl-phosphatidylglycerol.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Molecular characterization and analysis of the biosynthetic gene cluster for the azoxy antibiotic valanimycin

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Stimulation of delta-Aminolevulinic Acid Formation in Algal Extracts by Heterologous RNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

tRNA recognition by glutamyl-tRNA reductase.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

Domain-specific recruitment of amide amino acids for protein synthesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.11.045

21 January 2018

delta-Aminolevulinic acid-synthesizing enzymes need an RNA moiety for activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid specificity in translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical characterization of VlmL, a Seryl-tRNA synthetase encoded by the valanimycin biosynthetic gene cluster

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoacyl-tRNA recognition by the leucyl/phenylalanyl-tRNA-protein transferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable Analogues of Aminoacyl-tRNA for Inhibition of an Essential Step of Bacterial Cell-Wall Synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chlorophyll biosynthesis in Chlamydomonas starts with the formation of glutamyl-tRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of the peptidoglycan of bacterial cell walls. VII. Incorporation of serine and glycine into interpeptide bridges in Staphylococcus epidermidis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and properties of valanimycin, a new azoxy antibiotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of RNA-dependent recruitment of glutamine to the genetic code

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ammonia channel couples glutaminase with transamidase reactions in GatCAB

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of the peptidoglycan of bacterial cell walls. VI. Incorporation of L-threonine into interpeptide bridges in Micrococcus roseus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic conversion of glutamate to delta-aminolevulinic acid in soluble extracts of Euglena gracilis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of predictions for the catalytic mechanism of ribosomal peptidyl transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19925795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.FEBSLET.2009.11.045

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