Independent impacts of aging on mitochondrial DNA quantity and quality in humans. (Q46272203)

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scientific article published on 21 November 2017

Language	Label	Description	Also known as
English	Independent impacts of aging on mitochondrial DNA quantity and quality in humans.	scientific article published on 21 November 2017

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scholarly article

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29157198%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Independent impacts of aging on mitochondrial DNA quantity and quality in humans (English)

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3 April 2020

mitochondrial DNA

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1

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3 April 2020

4

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3 April 2020

author name string

Yiqin Wang

2

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3 April 2020

Kaixiong Ye

3

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3 April 2020

Zhenglong Gu

5

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3 April 2020

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publication date

21 November 2017

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3 April 2020

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3 April 2020

18

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3 April 2020

1

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3 April 2020

890

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PMC publication ID

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3 April 2020

Mammalian Mitochondria and Aging: An Update

1 reference

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24 May 2018

Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts.

1 reference

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24 May 2018

The rise of mitochondria in medicine

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24 May 2018

HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing

1 reference

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24 May 2018

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

1 reference

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24 May 2018

Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck

1 reference

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24 May 2018

Mitochondrial DNA copy number variation across human cancers

1 reference

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24 May 2018

Low Mitochondrial DNA Copy Number is Associated With Adverse Clinical Outcomes in Peritoneal Dialysis Patients.

1 reference

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24 May 2018

Correlates of Peripheral Blood Mitochondrial DNA Content in a General Population

1 reference

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24 May 2018

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

1 reference

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24 May 2018

Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease

1 reference

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24 May 2018

The UK10K project identifies rare variants in health and disease

1 reference

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24 May 2018

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools

1 reference

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24 May 2018

Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations

1 reference

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24 May 2018

From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline

1 reference

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24 May 2018

Maternally transmitted mitochondrial DNA mutations can reduce lifespan

1 reference

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24 May 2018

Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing.

1 reference

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24 May 2018

Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies

1 reference

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24 May 2018

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

1 reference

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24 May 2018

Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging

1 reference

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24 May 2018

Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals

1 reference

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24 May 2018

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5697406

24 May 2018

Mitochondrial metabolism and diabetes

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24 May 2018

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis.

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24 May 2018

Mitochondrial DNA disease-molecular insights and potential routes to a cure

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24 May 2018

Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations

1 reference

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24 May 2018

A general framework for estimating the relative pathogenicity of human genetic variants

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24 May 2018

Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy

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24 May 2018

Somatic mtDNA mutation spectra in the aging human putamen

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24 May 2018

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

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24 May 2018

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

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24 May 2018

The hallmarks of aging

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24 May 2018

Sequence kernel association tests for the combined effect of rare and common variants

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24 May 2018

The role of mitochondria in aging

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24 May 2018

Mitochondrial dysfunction and the inflammatory response

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24 May 2018

Human mitochondrial DNA: roles of inherited and somatic mutations

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24 May 2018

Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data

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24 May 2018

The UK Adult Twin Registry (TwinsUK Resource)

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24 May 2018

Ageing as a risk factor for disease

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24 May 2018

Cohort profile: the 'children of the 90s'—the index offspring of the Avon Longitudinal Study of Parents and Children

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24 May 2018

Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis

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24 May 2018

Fast gapped-read alignment with Bowtie 2

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24 May 2018

The role of DNA damage and repair in aging through the prism of Koch-like criteria.

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24 May 2018

Mitochondria and the autophagy-inflammation-cell death axis in organismal aging

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Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance.

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24 May 2018

Mitochondrial DNA mutations in disease and aging

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24 May 2018

Telomere dysfunction induces metabolic and mitochondrial compromise.

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24 May 2018

Neutral mitochondrial heteroplasmy and the influence of aging

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24 May 2018

The energetics of genome complexity

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24 May 2018

Survival in critical illness is associated with early activation of mitochondrial biogenesis

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24 May 2018

OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules

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24 May 2018

The Sequence Alignment/Map format and SAMtools

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24 May 2018

Ancient mtDNA genetic variants modulate mtDNA transcription and replication

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24 May 2018

Number matters: control of mammalian mitochondrial DNA copy number

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24 May 2018

Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review

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The contribution of ApoB and ApoA1 measurements to cardiovascular risk assessment

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24 May 2018

Mitochondrial membrane permeabilization in cell death

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24 May 2018

An enhanced MITOMAP with a global mtDNA mutational phylogeny

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24 May 2018

Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers

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24 May 2018

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

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24 May 2018

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

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24 May 2018

Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis

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24 May 2018

The incomplete natural history of mitochondria

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Neuronal degeneration and mitochondrial dysfunction

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Mitochondrial threshold effects.

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24 May 2018

Hypervariable sites in the mtDNA control region are mutational hotspots

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24 May 2018

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24 May 2018

Detection of a specific mitochondrial DNA deletion in tissues of older humans

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24 May 2018

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

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24 May 2018

Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs

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The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease.

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15 August 2018

Mitochondrial DNA copy number in peripheral blood is associated with cognitive function in apparently healthy elderly women

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Role of intracellular buffering power on the mitochondria-cytosol pH gradient in the rat liver perfused at 4 degrees C

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Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart

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based on heuristic

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Bicarbonate-carbon dioxide buffer system: a determinant of the mitochondrial pH gradient

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Comparison of WBC, ESR, CRP and PCT serum levels in septic and non-septic burn cases

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inferred from PubMed ID database lookup

Identifiers

10.1186/S12864-017-4287-0

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29157198%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Dimensions Publication ID

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12864-017-4287-0

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29157198%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29157198%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

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