A role for noncoding variation in schizophrenia (Q34632245)

3 August 2017

title

A role for noncoding variation in schizophrenia (English)

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3 August 2017

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Jane Worthington

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Georgios Voloudakis

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Kristen J Brennand

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Douglas M Ruderfer

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Leonid Padyukov

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Lars Klareskog

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Peter K Gregersen

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3 August 2017

Eric E Schadt

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Pamela Sklar

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Robert M Plenge

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Eli A Stahl

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3 August 2017

Katherine A Siminovitch

object named as

Katherine A Siminovitch

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3 August 2017

Soumya Raychaudhuri

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3 August 2017

Panos Roussos

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3 August 2017

Shaun M Purcell

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3 August 2017

Amanda C Mitchell

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3 August 2017

John F Fullard

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3 August 2017

Venu M Pothula

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3 August 2017

Jonathan Tsang

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3 August 2017

Anastasios Georgakopoulos

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3 August 2017

Alexander Charney

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3 August 2017

Yukinori Okada

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3 August 2017

Menachem Fromer

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3 August 2017

Nikolaos K Robakis

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Schahram Akbarian

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3 August 2017

publication date

6 November 2014

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3 August 2017

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3 August 2017

page(s)

1417-1429

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describes a project that uses

3 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4255904/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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A polygenic burden of rare disruptive mutations in schizophrenia

7 July 2018

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De novo mutations in schizophrenia implicate synaptic networks

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood

7 July 2018

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7 July 2018

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CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls

7 July 2018

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7 July 2018

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Chromatin marks identify critical cell types for fine mapping complex trait variants

7 July 2018

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CACNA1C as a risk factor for schizotypal personality disorder and schizotypy in healthy individuals

7 July 2018

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Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The impact of CACNA1C allelic variation on effective connectivity during emotional processing in bipolar disorder

7 July 2018

1 reference

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Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

7 July 2018

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Calcium signaling in neuronal development

7 July 2018

1 reference

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Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue

7 July 2018

1 reference

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Modelling schizophrenia using human induced pluripotent stem cells

7 July 2018

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Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

7 July 2018

1 reference

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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

7 July 2018

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The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

7 July 2018

1 reference

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Genetic Variation in CACNA1C Affects Brain Circuitries Related to Mental Illness

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Mediator and cohesin connect gene expression and chromatin architecture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Genome-wide association study of bipolar I disorder in the Han Chinese population

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Common regulatory variation impacts gene expression in a cell type-dependent manner

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Histone modifications at human enhancers reflect global cell-type-specific gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Whole-genome association study of bipolar disorder

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Differential targeting of the L-type Ca2+ channel alpha 1C (CaV1.2) to synaptic and extrasynaptic compartments in hippocampal neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Chromosomal contact permits transcription between coregulated genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

Brain function in carriers of a genome-wide supported bipolar disorder variant

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255904

10.1016/J.CELREP.2014.10.015

26 October 2018

Identifiers

DOI

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3 August 2017

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3 August 2017

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