The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system. (Q34973870)

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English	The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system.	scientific article

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scholarly article

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14 December 2019

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Europe PubMed Central

The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12385889%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Luca Maria Neri

1

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14 December 2019

Silvano Capitani

3

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14 December 2019

author name string

Paola Borgatti

2

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14 December 2019

Alberto M Martelli

4

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14 December 2019

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publication date

1 October 2002

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14 December 2019

number of pages

8

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Biochimica et Biophysica Acta

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14 December 2019

1584

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14 December 2019

2-3

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14 December 2019

73-80

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12385889%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Signalling through phosphoinositide 3-kinases: the lipids take centre stage

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinases in tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phospholipid signalling in the nucleus. Een DAG uit het leven van de inositide signalering in de nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The generation of lipid signaling molecules in the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear phospholipase C and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Re-examination of the mechanisms regulating nuclear inositol lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and function of 3-phosphorylated inositol lipids

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

PTEN: life as a tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of phosphatidylinositol 3-kinase with nuclear transcription sites in higher plants.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular signals in anti-apoptotic survival pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Erythropoietin-induced erythroid differentiation of K562 cells is accompanied by the nuclear translocation of phosphatidylinositol 3-kinase and intranuclear generation of phosphatidylinositol (3,4,5) trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that 3'-phosphorylated polyphosphoinositides are generated at the nuclear surface: use of immunostaining technique with monoclonal antibodies specific for PI 3,4-P(2).

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

cDNA cloning of porcine p42IP4, a membrane-associated and cytosolic 42 kDa inositol(1,3,4,5)tetrakisphosphate receptor from pig brain with similarly high affinity for phosphatidylinositol (3,4,5)P3.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and functional characterization of a human homologue of centaurin-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphoinositide 3-kinase in rat liver nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a G protein-activated phosphoinositide 3-kinase in vascular smooth muscle cell nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Presence and activation of nuclear phosphoinositide 3-kinase C2beta during compensatory liver growth

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and Function in the Nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear bodies: multifaceted subdomains of the interchromatin space.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-Kinase in HL-60 Nuclei Is Bound to the Nuclear Matrix and Increases During Granulocytic Differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Monocytic Differentiation of HL-60 Cells Is Characterized by the Nuclear Translocation of Phosphatidylinositol 3-Kinase and of Definite Phosphatidylinositol-Specific Phospholipase C Isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The Erythropoietin Receptor: Structure, Activation and Intracellular Signal Transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 4,5-bisphosphate reverses the inhibition of RNA transcription caused by histone H1.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of phosphatidylinositol 3-kinase in nuclear translocation of protein kinase C zeta induced by C2-ceramide in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Transport of protein kinase C isoforms to the nucleus of PC12 cells by nerve growth factor: association of atypical zeta-PKC with the nuclear matrix.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of Heterogeneous Ribonucleoprotein A1 as a Novel Substrate for Protein Kinase C ζ

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The dynamics of protein kinase B regulation during B cell antigen receptor engagement

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential phosphorylation at Ser473 and Thr308 of Akt-1 in rat brain following hypoglycemic coma

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of mature T-cell leukemia

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A role for nuclear PTEN in neuronal differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2802%2900300-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1388-1981(02)00300-1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12385889%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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https://api.fatcat.wiki/v0/release/ptdej4drnnc35nat2s5d3eeswu

24 November 2022

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12385889%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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