Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. (Q30868748)

27 June 2017

title

Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. (English)

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27 June 2017

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27 June 2017

T O'Neill

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27 June 2017

A J Dwyer

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27 June 2017

Y Ziv

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27 June 2017

D W Chan

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27 June 2017

S P Lees-Miller

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27 June 2017

R H Abraham

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27 June 2017

J H Lai

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27 June 2017

D Hill

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27 June 2017

Y Shiloh

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27 June 2017

G A Rathbun

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27 June 2017

language of work or name

English

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publication date

1 July 2000

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Journal of Biological Chemistry

27 June 2017

published in

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27 June 2017

volume

275

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27 June 2017

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27 June 2017

page(s)

22719-22727

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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

27 June 2017

cites work

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The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

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A role for ATR in the DNA damage-induced phosphorylation of p53

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DNA damage and the DNA-activated protein kinase

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Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

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Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation

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Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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The genetic defect in ataxia-telangiectasia

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.

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Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

21 January 2018

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The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

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The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

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Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 January 2018

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Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development

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ATM binds to beta-adaptin in cytoplasmic vesicles

21 January 2018

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ATM immunolocalization in mouse neuronal endosomes: implications for ataxia-telangiectasia.

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Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control.

21 January 2018

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

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ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

21 January 2018

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ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

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21 January 2018

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Interaction between ATM protein and c-Abl in response to DNA damage

21 January 2018

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

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Ataxia-telangiectasia: founder effect among north African Jews

21 January 2018

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Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

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DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus

21 January 2018

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Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

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DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

21 January 2018

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Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

21 January 2018

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ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

21 January 2018

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Localization of a portion of extranuclear ATM to peroxisomes

21 January 2018

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Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

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The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

21 January 2018

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Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

21 January 2018

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Positional cloning of the gene for Nijmegen breakage syndrome

21 January 2018

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Wee1+-like gene in human cells

21 January 2018

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Use of an oriented peptide library to determine the optimal substrates of protein kinases

21 January 2018

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ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M001002200

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27 June 2017

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