Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain. (Q48158450)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10413323%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

title

Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain (English)

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10 December 2019

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10 December 2019

K Y Lee

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10 December 2019

A W Clark

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10 December 2019

K Chapman

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10 December 2019

T Fung

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10 December 2019

R N Johnston

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10 December 2019

publication date

1 May 1999

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10 December 2019

published in

Neuroscience Research

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10 December 2019

volume

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10 December 2019

issue

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10 December 2019

page(s)

21-29

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Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

10 December 2019

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

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Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein

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Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

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Senile dementia of Alzheimer type characterized by laminar neuronal loss exclusively in the hippocampus, parahippocampus and medial occipitotemporal cortex.

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Proline-directed and non-proline-directed phosphorylation of PHF-tau.

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7 January 2021

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Identifiers

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10 December 2019

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