Molecular architecture of SMC proteins and the yeast cohesin complex (Q24296209)

Irr1p YIL026C

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Cohesin subunit SMC3 YJL074C

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Kleisin alpha YDL003W

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Condensin and cohesin display different arm conformations with characteristic hinge angles

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Andreas Hochwagen

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Christian H Haering

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Jan Löwe

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language of work or name

English

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publication date

April 2002

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773-88

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cites work

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Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin

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Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins

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7 January 2021

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

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Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

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7 January 2021

Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein

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7 January 2021

Bimodal activation of SMC ATPase by intra- and inter-molecular interactions

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7 January 2021

Dali: a network tool for protein structure comparison

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Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

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Movement of replicating DNA through a stationary replisome

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7 January 2021

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

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7 January 2021

Intermolecular DNA interactions stimulated by the cohesin complex in vitro: implications for sister chromatid cohesion

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7 January 2021

Identification of Xenopus SMC protein complexes required for sister chromatid cohesion

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7 January 2021

Crystal structure of the SMC head domain: an ABC ATPase with 900 residues antiparallel coiled-coil inserted

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7 January 2021

The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge

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7 January 2021

Cohesins: chromosomal proteins that prevent premature separation of sister chromatids

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7 January 2021

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

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7 January 2021

Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis

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7 January 2021

HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions

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7 January 2021

Pds5 cooperates with cohesin in maintaining sister chromatid cohesion.

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7 January 2021

A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction

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7 January 2021

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

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7 January 2021

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

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7 January 2021

Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells

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7 January 2021

Prokaryotic structural maintenance of chromosomes (SMC) proteins: distribution, phylogeny, and comparison with MukBs and additional prokaryotic and eukaryotic coiled-coil proteins

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7 January 2021

Characterization of vertebrate cohesin complexes and their regulation in prophase

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7 January 2021

Automated MAD and MIR structure solution

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7 January 2021

Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication

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7 January 2021

Cohesion between sister chromatids must be established during DNA replication

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7 January 2021

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

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7 January 2021

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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7 January 2021

Crystal structure of the N-terminal domain of MukB: a protein involved in chromosome partitioning

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7 January 2021

Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase

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7 January 2021