We investigate emergent conductive phenomena triggered by collinear antiferromagnetic orderings. We show that an up-down-zero spin configuration in a triangle cluster leads to linear and nonlinear spin conductivities even without the relativistic spin–orbit coupling; the linear spin conductivity is characterized by the Drude-type one, while the nonlinear spin conductivity is characterized by the Hall-type one. We demonstrate the emergence of both spin conductivities in the breathing kagome system consisting of a triangle cluster. The nonlinear spin conductivity becomes larger than the linear one when the Fermi level lies near the region where a small partial band gap opens. Our results indicate that collinear antiferromagnets with the triangle geometry give rise to rich spin conductive phenomena.

Cholangiocellular carcinoma (CCA) is the second most common primary liver cancer, with increasing incidence worldwide and inadequate therapeutic options. Intra- and extrahepatic bile ducts have distinctly different embryonic origins and developmental behavior, and accordingly intra- and extrahepatic CCAs (ICC vs. ECC) are molecularly different. A promising strategy in oncotherapy is targeted therapy, targeting proteins that regulate cell survival and proliferation; such as the MAPK/ERK and PI3K/AKT/mTOR signaling pathways. Inhibitors of these pathways have been tested previously in CCA cell lines. However, these cell lines could not be clearly assigned to ICC or ECC, and results indicated apoptosis induction by targeted therapeutics. We tested targeted therapeutics (selumetinib, MK2206) in three defined ICC cell lines (HuH28, RBE, SSP25). We observed cooperative effects of dual inhibition of the two pathways, in accordance with inhibition of phospho-AKT and phospho-ERK1/2 expression. Proliferation was blocked more effectively with dual inhibition than with each single inhibition, but cell numbers did not drop below baseline. Accordingly, we observed G1-phase arrest, but not apoptosis (cleaved caspase-3, AIFM1 regulation, subG1-phase) or necroptosis (phospho-MLKL). We conclude that dual inhibition of MAPK/ERK and PI3K/AKT/mTOR pathways is highly effective to block proliferation of ICC cell lines, but therapy must certainly be supplemented with standard therapies.

This study investigates the impacts of climate change policies on businesses across various sectors, aiming to understand how these regulations affect operational, financial, and strategic aspects of business management. Utilizing a mixed-methods approach, data was collected from 500 businesses through surveys and interviews, encompassing a wide range of industries, sizes, and geographic locations. The findings reveal a complex landscape where 30% of businesses report positive impacts, primarily in the renewable energy and technology sectors, citing increased demand for green products and improvements in energy efficiency. Conversely, 45% of businesses, especially from manufacturing and agriculture, experience negative impacts, including increased operational costs and regulatory compliance challenges. Notwithstanding, a significant majority of businesses are committed to enhancing their sustainability practices, viewing climate change policies as an opportunity for innovation and long-term growth. The study highlights the nuanced effects of climate change policies, emphasizing the need for sector-specific support measures to alleviate financial and operational burdens on negatively impacted businesses. Moreover, it points to a broader shift towards sustainability within the business community, suggesting that climate policies, despite their varied impacts, are driving significant changes in business strategies towards environmental stewardship.

In a recent paper: “On the time dependency of a₀” the authors claim that they have tested “one of the predictions of the Scale Invariant Vacuum (SIV) theory on MOND” by studying the dependence of the Modified Newtonian Dynamics (MOND) accelera- tion at two data sets, low-z (3.2 × 10⁻⁴ ≤ z ≤ 3.2 × 10⁻²) and high-z (0.5 ≤ z ≤ 2.5). They claim “both samples show a dependency of a₀ from z”. Here, the work men- tioned above is revisited. The explicit analytic expression for the z-dependence of the a0 within the SIV theory is given. Furthermore, the first estimates of the Ω_m within SIV theory give Ω_m = 0.28 ± 0.04 using the low-z data only, while a value of Ω_m = 0.055 is obtained using both data sets. This much lower Ωm leaves no room for non-baryonic matter! Unlike in the mentioned paper above, the slope in the z- dependence of A₀ = log10(a₀) is estimated to be consistent with zero Z-slope for the two data sets. Finally, the statistics of the data are consistent with the SIV predic- tions; in particular, the possibility of change in the sign of the slopes for the two data sets is explainable within the SIV paradigm; however, the uncertainty in the data is too big for the clear demonstration of a z-dependence yet.

The relationships between the relative abundances of chemical elements and their second ionization potentials, as well as their condensation temperatures, were analyzed using four published homogeneous abundance surveys of halo and thin disk stars. We selected 932 stars with effective temperatures ranging from 4900 K to 5900 K and used the abundances of 10 chemical elements common across all surveys: Mg, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, and Ni. The correlation coefficients between the relative abundances of these elements and their second ionization potentials and condensation temperatures were investigated in relation to metallicity and the stars' location in the Galaxy. The observed correlations may result from certain physical processes, such as the accretion of interstellar gas onto stellar atmospheres. We also analyzed the dependencies of relative abundances on second ionization potentials based on published abundance patterns in five halo stars. Evidence of charge-exchange reactions in the atmospheres of these stars was found. For more accurate determination of stellar ages from the abundance ratios of radioactive and stable chemical elements in stellar atmospheres, processes such as charge-exchange reactions and dust-gas separation should be considered in future detailed investigations. Additionally, changes in the chemical abundances in the atmospheres of halo stars after crossing the Galactic plane were found to be possible.

Hydrogen sulfide is present in active or extinct volcanic areas (mofettas). The habitable premises in these areas are affected by the presence of hydrogen sulfide, which, even in low concentrations, gives off a bad to unbearable smell. If the living spaces considered are closed enclosures, then a system can be designed to reduce the concentration of hydrogen sulfide. This paper presents a membrane way to reduce the hydrogen sulfide concentration to acceptable limits using a cellulosic derivative-propylene hollow fiber based composite membrane module. The cellulosic derivatives considered were carboxymethyl–cellulose (NaCMC), cellulose acetate (CA), methyl 2–hydroxyethyl–cellulose (MHEC), and 2–hydroxyethyl–cellulose (HEC). In the permeation module, hydrogen sulfide is captured with a solution of cadmium that forms cadmium sulfide, usable as a luminescent substance. The composite membranes were characterized by SEM, EDAX, FTIR, FTIR 2D maps, thermal analysis (TG and DSC) and from the perspective of hydrogen sulfide air removal performance. To determine the process performances, the variables were: the nature of the cellulosic derivative–polypropylene hollow fiber composite membrane, the concentration of hydrogen sulfide in the polluted air, the flow rate of polluted air, and the pH of the cadmium nitrate solution. Pertraction efficiency was maximum for the sodium carboxymethyl–cellulose (NaCMC)-polypropylene hollow fiber membrane, a hydrogen sulfide concentration in the polluted air of 20 ppm, polluted air flow rate of 50 L/min, and a pH of 2 and 4.

We propose a method of cooling nuclear spin systems of solid-state nanostructures by application of a time-dependent magnetic field synchronized with spin fluctuations. Optical spin noise spectroscopy is considered as the method of fluctuation control. Depending on the mutual orientation of the oscillating magnetic field and the probe light beam, cooling might be either provided by dynamic spin polarization in an external static field or result from population transfer between spin levels without build-up of a net magnetic moment (“true cooling”).

Thorium is a weak radioactive element, but the control of its concentration in natural aqueous systems is of great interest for health, because it is a toxic heavy metal. The present paper presents the recovery of thorium from diluted synthetic aqueous systems by nanofiltration. The membranes used for nanofiltration of systems containing thorium species are composites containing 4′-Aminobenzo-15-crown-5 ether (ABCE) and sulfonated poly–ether–ether–ketone (sPEEK). The composite membranes (ABCE–sPEEK) were characterized by scanning electron microscopy (SEM), energy dispersive X–ray spectroscopy EDAX, thermal analysis (TG and DSC) and from the perspective of thorium removal performance. To determine the process performances, the variables were: the nature of the composite membrane, the concentration of thorium in the aqueous systems, the rotation speed of the stirrer, the pressure and the pH of the thorium aqueous system. When using pure water, a permeate flux value of 12 L·m⁻2 h⁻1 was obtained for sPEEK membrane, and up to 15 L·m⁻2 h⁻1 for the ABCE–sPEEK composite membrane. The use of mechanical stirring, with a propeller stirrer, leads to an increase in the permeate flux of pure water by about 20 % for each of the studied membrane. Depending on the concentration of thorium and the pH of the feed solution, retentions between 84.9 % and 98.4 % were obtained. An important observation is the retention jump at pH 2 for the ABCE–sPEEK composite membrane. In the paper, a thorium ion retention mechanism is proposed for the sPEEK membrane and the ABCE–sPEEK composite membrane.

As an International Union for Conservation of Nature (IUCN) voluntary reviewer of the natural World Heritage sites nominations focusing on criteria (vii) superlative natural phenomena and (viii) geological history I had the opportunity of evaluating 13 nominations from 12 countries from 2009 - 2022 from the Central Highlands of Sri Lanka to the Vatnajokull National Park Iceland. An early appreciation of the natural history and landscapes were developed as a geologist studying, working and visiting various areas in the USA and Canada. Further experience, as an academic in Sri Lanka and Australia, where I also had the opportunity of various assignments and meetings that afforded field trips and study tours to many World Heritage sites in Asia, Africa, South America and Europe. In this paper, I highlight the following sites that were subject to IUCN World Heritage evaluations and their potential for geo-education: Central Highlands Sri Lanka, China Danxia, Ningaloo Australia, Trang An Vietnam, Lut Desert Iran, Barberton South Africa, Trondek Klondike Canada, Vatnajokull Iceland, Classic Karst Slovenia, Sof Omar Ethiopia, Ha Long Bay – Cat Ba Archipelago, Vietnam and Evaporitic Karst Caves of Northern Apennines, Italy. From these experiences it is apparent that this relevant topic, the conservation of nature, should be an important part of the geoscience’s study curriculum along with other social and environmental subjects.

Magneto-electrochemistry (MEC) is a unique paradigm in science, where electrochemical experiments are carried out as a function of an applied magnetic field, creating a new horizon of potential scientific and technological applications. Over the time, detailed understanding of this research domain was developed to identify and rationalize the possible effects exerted by a magnetic field on the various microscopic processes occurring in an electrochemical system, such as: electrolyte properties governed by charge-transfer process (electric conductivity, viscosity, and diffusivity), mass transfer, electrochemical kinetics and on the structure/quality of products formed either at the working electrode or in the electrochemical cell. Particularly, magnetic field controlled chiral architecture obtained from deposited metal, alloys and catalyst and their excellent enantio-recognition in experimental frame is highly appealing. Interestingly, Hall effect was also demonstrated in electrolytic medium via an impressive experimental technique which is being employed for further theoretical understanding in the field of magneto-electrochemical science. Later, a highly reproducible local temperature variation was observed in electrochemical electrolytes exposed to perpendicular magnetic and electric fields. However, until recent studies, none of the above mentioned reports considered the possibility of a spin-dependent related charge-transfer process. Recent experimental and theoretical studies reveal that electron’s transmission through chiral molecules is spin-selective and this effect has been referred to as chiral-induced spin-selectivity (CISS) effect. The CISS effect pave the way for the building up of a system characterized by a net magnetic moment exploiting the spin-filtering ability of chiral molecules. This interplay between chirality and magnetism may shed light on fundamental scientific aspects underlying the enantio-recognition and highly efficient electron-transfer that occurs in biological process.

Using the unique combination of atomically resolved atom probe tomography (APT) and volume averaged neutron (resonance) spin echo (NRSE and NSE) experiments, the influence of nano-scaled clusters on the spin relaxation in spin glasses was studied. For this purpose, the phase transition from the paramagnetic phase to the spin glass phase in a Fe-Cr spin glass with a composition of Fe_17.8Cr_82.2 was studied in detail by means of NRSE. The microstructure was characterised by APT measurements, which show local concentration fluctuations of Fe and Cr on a length scale of 2 to 5 nm, which lead i) to the coexistence of ferro- and anti-ferromagnetic clusters and ii) a change of the magnetic properties of the whole sample, even in the spin glass phase, where spins are supposed to be randomly frozen. We show that a generalized spin glass relaxation function, which was successfully used to describe the phase transition in diluted spin glasses, can also be used for fitting the spin dynamics in spin glasses with significant concentration fluctuations.

Intercalation of noble metals can produce giant Rashba-type spin-orbit splittings in graphene. The spin-orbit splitting more than 100 meV has not yet been achieved in graphene on a metallic or a semiconductor substrate. Here, we report the p-type graphene obtained by Pt intercalation of zero-layer graphene on SiC substrate. The spin splitting of ∼200 meV was observed at a wide range of binding energies. Comparing the results of theoretical studies of different models with the experimantal ones measured by spin-ARPES, XPS and STM methods, we came to the conclusion that inducing giant spin-orbit splitting requires not only a fairly close arrangement of graphene to Pt layer, but also the presence of graphene corrugation caused by non-flat Pt layer. This makes it possible to find a compromise between strong hybridization and increased spin-orbit interaction. In our case, this is achieved by forming Pt submonolayer ordered on a nanometer scale under graphene.

We present an experimental study of the coherence properties of a single heavy-hole spin qubit formed in one quantum dot of a gated GaAs/AlGaAs double quantum dot device. We use a modified spin-readout latching technique in which the second quantum dot serves both as an auxiliary element for fast spin-dependent readout within a 200ns time window and also as a register for storing the spin-state information. To manipulate the single-spin qubit we apply sequences of microwave bursts of various amplitudes and durations to make Rabi, Ramsey, Hahn-echo, and CPMG measurements. As a result of the qubit manipulation protocols combined with the latching spin readout, we determine and discuss the achieved qubit coherence times: T1, T_Rabi, T2*, and T_CPMG vs microwave excitation amplitude, detuning and additional relevant parameters

The Einstein’s Boxes paradox was developed by Einstein, de Broglie, Heisenberg, and others to demonstrate the incompleteness of the Copenhagen Formulation of quantum mechanics. I explain the paradox using the Copenhagen Formulation. I then show how a Time-Symmetric Formulation of quantum mechanics resolves the paradox in the way envisioned by Einstein and de Broglie. Finally, I describe an experiment that can distinguish between these two formulations.

Materials based on platinum metals with very good catalytic activity were tested in the reduction of p–nitrophenol (pNP) to p–aminophenol (pAP). The majority of presented catalytic materials are based on the adsorption of p–nitrophenol on the surface of the catalyst simultaneously with molecular hydrogen, coming from sodium borohydride in an aqueous medium, which reduces it. In the present paper, a catalytic material based on osmium dispersed in n–decanol or n–dodecanol is presented, which also works as an emulsion membrane, for the absorption of p–nitrophenol and molecular hydrogen at the n–alcohol aqueous solution interface. The hydrogenation of p–nitrophenol is carried out in a reaction and separation column in which the acid receiving phase emulsion is dispersed in the osmium nanodispersion, in n–alcohols. This emulsion circulates from the base of the column to its upper part in co-current or counter-current with the source phase consisting of p–nitrophenol and sodium borohydride. Experiments show that the circulation of counter-current phases is superior to that in co-current, and the emulsion based on n–decanol is more efficient than the one based on n–dodecanol. The increase in the pH difference between the source and receiving phases leads to the increase in the conversion of p–nitrophenol to p–aminophenol. The efficiency of separation of the reaction product in the receiving phase is lower than the conversion at the same operating time. The apparent catalytic rate constant (kapp) of the new catalytic material based on the emulsion membrane with nanodispersion of osmium nanoparticles (0.1×10−3 for n–dodecanol and 0.9×10−3 for n-decanol) is lower by an order of magnitude compared to those based on adsorption on catalysts from platinum metal group. The advantage of the tested membrane catalytic material is that it extracts p–aminophenol in the acid receiving phase. The paper proposes a mechanism of the studied reduction system.

The electron of magnetic spin −1/2 is a Dirac fermion of a complex four-component spinor field. Though it is effectively addressed by relativistic quantum field theory, an intuitive form of the fermion still remains lacking. In this novel undertaking, the fermion is examined within the boundary posed by a recently proposed MP model of a hydrogen atom into 4D space-time. Such unorthodox process conceptually transforms the electron to the four-component spinor of non-abelian in both Euclidean and Minkowski space-times. Supplemented by several postulates, the relativistic and non-relativistic applications of the model are explored from an alternative perspective. The outcomes have important implications towards defining the spin-orbit coupling of particles from external light interactions. These findings, if considered could consolidate properly the fundamentals of the quantum state of matter from an alternative perspective using quantum field theory application and they warrant further investigations.

The quasi-two-dimensional organic charge-transfer salt κ-(BEDT-TTF)₂Cu₂(CN)₃ is one of the prime candidates for a quantum spin-liquid due the strong spin frustration of its anisotropic triangular lattice in combination with its proximity to the Mott transition. Despite intensive investigations of the material's low-temperature properties, several important questions remain to be answered. Particularly puzzling are the 6 K anomaly and the enigmatic effects observed in magnetic fields. Here we report on low-temperature measurements of lattice effects which were shown to be particularly strongly pronounced in this material (R. S. Manna et al., Phys. Rev. Lett. 104, 016403 (2010)). A special focus of our study lies on sample-to-sample variations of these effects and their implications on the interpretation of experimental data. By investigating overall nine single crystals from two different batches, we can state that there are considerable differences in the size of the second-order phase transition anomaly around 6 K, varying within a factor of 3. In addition, we find field-induced anomalies giving rise to pronounced features in the sample length for two out of these nine crystals for temperatures T < 9 K. We tentatively assign the latter effects to B-induced magnetic clusters suspected to nucleate around crystal imperfections. These B-induced effects are absent for the crystals where the 6 K anomaly is most strongly pronounced. The large lattice effects observed at 6 K are consistent with proposed pairing instabilities of fermionic excitations breaking the lattice symmetry. The strong sample-to-sample variation in the size of the phase transition anomaly suggests that the conversion of the fermions to bosons at the instability is only partial and to some extent influenced by not yet identified sample-specific parameters.

Current-induced field-free magnetic switching using spin-orbit torque has been an important topic for decades due to both academic and industrial interest. Most research has focused on introducing symmetry breakers, such as geometrical and compositional variation, pinned layer, and symmetry-broken crystal structures, which add complexity to the magnetic structure and fabrication process. We designed relatively simple magnetic structure, composed of a [Co/Pt] multilayer and a Co layer with perpendicular and in-plane magnetic anisotropy, respectively, with a Cu layer between them. Current-induced deterministic magnetic switching was observed in this magnetic system. The system is advantageous for its easy control of the parameters to achieve the optimal condition for magnetic switching. The balance between magnetic anisotropic strength and interlayer coupling strength is found to provide the optimal condition. This simple design and easy adjustability opens various possibilities for magnetic structures in spin-based electronics applications using spin-orbit torque.

State transition in the multiple-levels system has the great potential applications in the quantum technology. In this article we employ a deterministic approach in complex space to analyze the dynamics of the 1s-2p electron transition in the hydrogen atom. The electron’s spin motion is embodied in the framework of quantum Hamilton mechanics that allows us to examine the transition dynamics more precisely. The transition is driven by an oscillating electric field in the z-direction. The electron’s transition process can be visualized by monitoring its motion in the complex space. The quantum potential and the total energy proposed in this paper provide new indices to observe the dynamic changes of electrons in the transition process.

First, we examine how spin is treated in special relativity and the necessity of introducing spin supplementary conditions (SSC) and how they are related to the choice of a center-of-mass of a spinning particle. Next, we discuss quantum electrodynamics and the Foldy-Wouthuysen transformation which we note is a position operator identical to the Pryce-Newton-Wigner position operator. The classical version of the operators are shown to be essential for the treatment of classical relativistic particles in general relativity, of special interest being the case of binary systems (black holes/neutron stars) which emit gravitational radiation.

A structure-based view on mesons is given, based upon the concept of an archetype quark, described as a pointlike source producing an energy flux, the spatial description of which is derived from Dirac’s second dipole moment. This enables to conceive the archetype meson (pion) as a structure that behaves as a one-body anharmonic quantum mechanical oscillator. All mesons appear being excitations of the archetype, thereby allowing a calculation of the mass spectrum without the use of empirical parameters for the masses of the quark flavors. This includes a physically comprehensible analysis of the spin-spin interaction between quarks. It also provides a solution for the eta-etaprime puzzle. Next to this, it is shown that quite some particles that are presently regarded as elementary, have a common root and can be traced back to a few archetypes only.

Surface–subsurface soil-rock modeling is crucial for infrastructure design and groundwater yield optimization, especially in the complex crystalline basement terrains of Penang Island, Malaysia. This study conducted large-scale characterization of soil-rock profiles using ERT, SRT, rock quality designation, and soil penetration test (SPT N-values) data, optimized through regression modeling. The approach effectively identified soil-rock structures and their suitability to prevent structural failures and enhance groundwater productivity. Correlations between borehole lithologic logs and velocity–resistivity models revealed distinct soil compositions across the study area. The results highlighted thick, saturated, and loose silty to sandy bodies in the eastern to northern sections, contrasting with sandy compositions and penetrative fractures in the southern part. The study also found good correlations between rock mass quality and N-values for different soil types. Depths of intra-bedrock weathered/fractured units varied between 12 and >35 m. This has significant implications for determining optimal foundation depths in the study area. Groundwater productivity was associated with intra-bedrock planes of weakness at depths exceeding 40 m. Overall, this study developed empirical relations between geophysical and geotechnical parameters for wet tropical granitic terrains, filling critical gaps in understanding subsurface characteristics.

In particle physics, spin is an intrinsic form of angular momentum carried by the elementary particles. It is believed that spin is a solely quantum-mechanical phenomenon, which does not have a counterpart in classical mechanics. We have derived the simplest equations of spin and magnetic moment of a charged elementary particle. These formulas enable us to understand the physical nature of the spin and the structure of elementary particles. It is shown that the electron and muon are in the shape of a thin ring with a circular cross section (torus), and the proton is in the form of a ring with a non-circular cross section (toroid). The connection between the photon’s spin of and the propagation of electromagnetic waves is considered.

The small business sector in Kazakhstan demonstrates dynamic growth, but its sustainable development in modern conditions requires activation from government agencies, society and entrepreneurs themselves The purpose of the article is to study the development of small entrepreneurship in Kazakhstan and develop a mechanism for sustainable development based on network interaction "business entities - society-state" with the identification of priority areas of development based on a rating approach. The methods of bibliographic analysis of scientific literature, statistical, correlation analysis, survey, comparative analysis, ranking based on data normalization were used. The results revealed the need to formalize indicators of sustainable development of the small business sector in strategic development programs; create conditions, support, explain the importance and prospects of investing in sustainable innovations by small businesses; form a balanced strategy for achieving carbon neutrality based on network interaction "business entities - society-state" with the identification of priority areas of development based on a rating approach to ensure transparency and publicity of decisions made. Conclusions are made about the need to popularize sustainable development among business entities, stimulate investment activity through government participation, legislative regulation of public presentation of non-financial reporting, and assist society in the formation of an ESG culture.

In this review, we trace the evolution of the quantum spin-wave theory treating non-collinear spin configurations. Non-collinear spin configurations are consequences of the frustration created by competing interactions. They include simple chiral magnets due to competing nearest-neighbor (NN) and next-NN interactions and systems with geometry frustration such as the triangular antiferromagnet and the Kagomé lattice. We review here spin-wave results of such systems and also systems with the Dzyaloshinskii-Moriya interaction. Accent is put on these non-collinear ground states which have to be calculated before applying any spin-wave theory to determine the spectrum of the elementary excitations from the ground states. We mostly show results from a self-consistent Green’function theory to calculate the spin-wave spectrum and the layer magnetizations at finite T in two and three dimensions as well as in thin films with surface effects. Some new unpublished results are also included. Analytical details and the validity of the method are shown and discussed.

In previous papers we have shown how Schrödinger’s equation which includes an electromagnetic field interaction can be deduced from a fluid dynamical Lagrangian of a charged potential flow that interacts with an electromagnetic field. The quantum behaviour was derived from Fisher information terms which were added to the classical Lagrangian. It was thus shown that a quantum mechanical system is driven by information and not only electromagnetic fields. This program was applied also to Pauli’s equations by removing the restriction of potential flow and using the Clebsch formalism. Although the analysis was quite successful there were still terms that did not admit interpretation, some of them can be easily traced to the relativistic Dirac theory. Here we repeat the analysis for a relativistic flow, pointing to a new approach for deriving relativistic quantum mechanics.

Photoluminescent (PL) layers and electroluminescent (EL) systems have been extensively explored for constructing flat panels, screen monitors, and lighting systems. Due to their optical properties, our group is interested in the relationship between optical properties and dielectric constant is converted due to thermal change. In this study, we prepared a zinc sulfide (ZnS) fluorescent film on barium-calcium zirconium titanate ceramics. BCZT0.85 (Ba0.85Ca0.15Zr0.1Ti0.9O3) and BCZT0.9 (Ba0.9Ca0.1Zr0.1Ti0.9O3) were prepared using the solid-state reaction method for the dielectric layer. The BCZT powders were calcined at 1200 and 1250 °C and dwell times of 2 and 4h. The phase formation and microstructure characteristics were then determined using X-ray diffraction and scanning electron microscopy, respectively. The dielectric behavior and optical properties rela-tionship was then studied to determine the composition and optimal conditions for further use as thermal detectors in electric vehicle battery packs. All BCZT powders exhibited the tetragonal phase, which was confirmed by JCPDS No. 01-079-2265. The dielectric constant increased with increasing calcining temperature or dwell time. The dielectric properties showed the BCZT0.85 ceramic sintered had the maximum dielectric constant of 15342 at calcine temperature of 1250 °C for 4h. Therefore, in this study, this condition was optimal for preparing the dielectric film. The maximum dielectric constant film is 42. The electroluminescence intensity of the samples increased in a temperature-dependent manner, with the highest EL intensity at 80 °C. Moreover, the electroluminescence intensity value was enhanced with the increase of the dielectric constant. Our results show promise for developing applications for Opto-thermal sensors.

Electrons moving at slow speeds much lower that the speed of light are described by a wave function which is a solution of Pauli’s equation. This is a low velocity limit of the relativistic Dirac equation. Here we compare two approaches, one which is the more conservative Copenhagen’s interpretation denying a trajectory of the electron but allowing a trajectory to the electron expectation value through Ehrenfest theorem. The said expectation value is of course calculated using a solution of Pauli’s equation. A less orthodox approach is championed by Bohm, and attributes a velocity field to the electron also derived from the Pauli wave function. It is thus interesting to compare the trajectory followed by the electron according to Bohm and its expectation value according to Ehrenfest. Both similarities and differences will be considered.

Spin crossover (SCO) complexes are in the forefront of image, memory and sensing devices, with applications already established since for thirty years. In order to reach magnetic multistability conditions, the high-spin (HS) and low-spin (LS) states have to be carefully balanced by ligand field stabilization and spin pairing energies. Both of these effects could be effectively modelled by electronic structure theory, if the description would be accurate enough to describe these concurrent influences to within a few kJ/mol. Such a milestone would allow for the in silico-driven development of SCO complexes. However, so far, the ab initio simulation of such systems has been dominated by general gradient approximation density functional calculations. The latter can only provide the right answer for the wrong reasons, given that the LS states are grossly stabilized. In this contribution, we explore different venues for the parameterisation of hybrid functionals. A fitting set is provided on the basis of explicitly correlated coupled cluster calculations, with single- and multi-dimensional fitting approaches being tested to selected classes of hybrid functionals (hybrid, range separated and local hybrid). Promising agreement to benchmark data is found for a rescaled PBE0 hybrid functional and a local version thereof, with a discussion of different atomic exchange factors.

We investigate on the plasmons of monolayer MoS₂ in the presence of spin-orbit interactions (SOIs) under the random phase approximation. The theoretical study shows that two new and novel plasmonic modes can be achieved via inter spin sub-band transitions around the Fermi level duo to the SOIs. The plasmon modes are optic-like, which are very different from the plasmon modes reported recently in monolayer MoS₂, and the other two-dimensional systems. The frequency of such plasmons increases with the increasing of the electron density or the spin polarizability, and decreases with the increasing of the wave vectors q. Our results exhibit some interesting features which can be utilized to the plasmonic and terahertz devices based on monolayer MoS₂.

We show how the Poincar\'e--Riemann--Hilbert boundary-value problem enables us to construct effective estimates of the potential in the Schr\"odinger equation. The apparatus of the three-dimensional inverse problem of quantum scattering theory is developed for this. It is shown that the unitary scattering operator can be studied as a solution of the Poincar\'e--Riemann--Hilbert boundary-value problem. This allows us to go on to study the potential in the Schr\"odinger equation

K-Rb-83Kr based atomic co-magnetometer for measuring moving MEGs is theoretically studied in this paper. Parameters such as the spin exchange rates, the spin dephasing rates and the polarization of the nuclear spins are studied to configure the co-magnetometer. Results show that the nuclear spin could generate around 700 nT magnetic field under which the nuclear spin could compensate wide range of magnetic fields. We also showed the hybrid optical pumping vapor cell fabrication process in this paper. Alkali metals were mixed in a glove box and then was connected to the alkali vapor cell fabrication system. The vapor cell fabrication process is illustrated in this paper.

The purpose of this paper was to examine the differences in using agricultural entrepreneurship support and in how it relates to characteristics such as the agrarian structure, socioeconomic de-velopment level and land use across the Polish territory. The analyses were carried out at district (poviat) level which is an intermediate administrative unit. The study found that the decisions on co-financing the measures dedicated to non-agricultural economic activity heavily depend on the agrarian structure. The highest levels of activity were witnessed in districts where the agrar-ian structure is particularly fragmented.

In this article, we show theoretically and experimentally the formation of spin-waves band gaps in a magnonic crystal that was implemented by the deposition of periodic micro-structured strips of magnetite nanoparticles. A theoretical model describing the spectra of the transmitted spin-waves bandgaps is proposed. This is achieved using a simple model based on microwave transmission line theory and considering the presence of micro-structured strips of magnetite nanoparticles on the surface. Such magnonic crystal of equally spaced micro-structured strips of magnetite nanoparticles on the surface of an yttrium iron garnet thin film has been implemented and measured. The periodic micro-structured nanoparticles are deposited on the surface of such yttrium iron garnet single-crystal film grown on a gallium-gadolinium garnet substrate via dip-coating technique. Propagation of magnetostatic surface spin-waves is studied and it is shown that the presence of such periodic structure leads to the formation of spin-wave band gaps in the transmission characteristics. The spin-wave detection has been carried out using a pair of microwave antennas and a vector network analyzer. The results show that the periodic structure formed by the magnetite strips modifies the spectra of the transmitted spin waves producing band gaps.

A substantial amount of phosphorus (P) in soil is not readily available for plant uptake. Certain species may enhance P availability from poorly soluble P forms. This research aimed to compare the P solubilization capacity of the soil of two Lupine species, L. albus, and L. angustifolius, with a control crop of oats (Avena strigosa L.). Plants were planted in pots in four soils with varying texture, organic matter content, acidity, and P availability. Phosphorus solubilization capacity was assessed on variations of P availability (PBray1) at four points in time, comparing soils with lupine to oat-containing soils and their baseline values. At harvest, measurements of plant shoot biomass included their shoot dry weight and some nutrient concentrations such as P, nitrogen (N), manganese (Mn), and lupine nitrogen fixation. Compared to soils containing oats, lupine soils significantly increased PBray1 concentrations; increments ranged from 0.9 to 5.4 mg kg-1, depending on species, sampling time, and soil type. Lupine-induced soil acidification did not fully explain this P increase., As a proxy measurement of organic acid exudation, Manganese concentration was high in both lupine species' shoot biomass; however, these legumes had divergent Mn accumulation responses to soil acidity and P availability. Nitrogen fixed quantity varied with Lupine species (105-240 mg pot-1) and soil type (60-240 mg pot-1). Lupinus albus had a higher ability to mobilize non-labile P and provide N through biological N fixation (BNF), positioning it as a suitable crop for diversifying Uruguay's agricultural crop rotation systems.

In this work, a generalized analogue to the Pauli spin matrices is presented and investigated. The proposed Hermitian spin matrices exhibit a general symmetry. The generalized spin projection operators are derived and the electrodynamics for hypothetical fermions are explored using the proposed spin matrices. The fermionic quantum Heisenberg model is constructed using the proposed spin matrices and comparative studies against simulation results using the Pauli spin matrices are conducted. Further analysis on key findings as well as discussions on extending the proposed spin matrix framework to describe hypothetical bosonic systems (spin-1) are provided.

In previous papers we have shown how Schr\"{o}dinger's equation which includes an electromagnetic field interaction can be deduced from a fluid dynamical Lagrangian of a charged potential flow that interacts with an electromagnetic field. The quantum behaviour was derived from Fisher information terms which were added to the classical Lagrangian. It was thus shown that a quantum mechanical system is drived by information and not only electromagnetic fields. This program was applied also to Pauli's equations by removing the restriction of potential flow and using the Clebsch formalism. Although the analysis was quite successful there were still terms that did not admit interpretation, some of them can be easily traced to the relativistic Dirac theory. Here we repeat the analysis for a relativistic flow, pointing to a new approach for deriving relativistic quantum mechanics.

In this study, the problem of overcoming the infinite energy barrier separating the bradyonic and tachyonic realms is investigated. Making use of the Majorana equation for particles with arbitrary spin and the Heisenberg uncertainty principle, it is proved that, under certain conditions of spatial confinement, quantum fluctuations allow particles with very small mass and velocity close to the speed of light to pass in the tachyonic realm, avoiding the problem of the infinite barrier (bradyon–tachyon tunnelling). This theoretical approach allows an avoidance of the difficulties encountered in quantum field theory when it is extended to particles with imaginary rest mass.

A superparamagnetic graphene oxide based drug carrier Fe3O4@SiO2/N–rGO was prepared through surface modification, material doping, and composite methods. This carrier has a large number of active sites, suitable for loading anticancer drugs, It can increase the drug load. Currently, the widely used drug in clinical use is epirubicin hydrochloride (EPI). The graphene based complex has a pH sensitive property and exhibits a pH sensitive property at pH=4.3. The release efficiency (RE) is 77.4%, making it suitable for drug release in cancerous acidic liquids. The physicochemical properties of drug carriers were studied using X–ray diffraction, Raman spectroscopy, and Fourier transform infrared spectroscopy. Electrochemical signals confirm that the anticancer drug EPI acts on the graphene plane through hydrogen bond interactions and π – π stacking.

The hydrocarbon generation potential of Chia Gara strata and their genetic link with produced oils from the Zagros basin are still not comprehensively investigated. Forty-seven rock samples from the Tithonian–Berriasian interval were subjected to geochemical analyses to infer organic matter enrichment, hydrocarbon potential, thermal maturity, and timing for hydrocarbon generation/expulsion and their implications regarding upcoming petroleum explorations in the Zagros basin. The results showed that the Chia Gara rock samples have fair to very-good generation potential, as confirmed by higher total organic carbon (TOC=0.68–3.95 wt%) and Rock-Eval (S1+S2=3.37–8.52 mg HC/g rock). The hydrogen index (HI=171–462) and Rock-Eval Tmax over 430 °C support the presence of Types II and mixed Types II/III kerogen. These results confirm the high generation potential of the Chia Gara Formation in the study region. 1D basin models of the KK–109 well show that over 55% of kerogens were converted into oil in the Cretaceous (77–67 Ma). Expulsion started from the Miocene until now (22–0 Ma), consistent with 0.71–0.80 of modeled Easy%Ro and 55–80 %TR. Consequently, this project confirms the potential oil expulsion from the Chia Gara Formation, which can be a resource for upcoming hydrocarbon investigation in the Zagros basin, Iraq.

Understanding how humans perceive animals is important for biodiversity conservation, however, only a few studies about this issue were carried out in South America. We selected two Brazilian cities to assess people’s perceptions of birds: Bauru (São Paulo, Brazil) and Belo Horizonte (Minas Gerais, Brazil). From the bird data we gathered, we developed a questionnaire and applied it between September 2020 and June 2021. The data obtained were analyzed by simple counts, Likert scale, and percentages. Also, open questions were placed on the Free Word Cloud Generator website. Our study confirmed that most respondents are aware of the importance of birds to ecological balance and that respondents had a generally positive attitude towards most of the bird species. However, they disliked exotic species such as the Domestic Dove and the House Sparrow, which are associated with disease, dirt, and disgust. Respondents also underestimated the number of birds that can live in urban areas and the song of birds is still a sense less explored and perceived by people. The concept of environmental perception seeks to cover aspects and understanding these human–biodiversity relationships is essential to successfully guide public policies, urban planning interventions, and environmental education activities.

We examine here the conductance changes associated with the change in spin state in a variety of different structures, using the example of the spin crossover complex [Fe(H2B(pz)2)2(bipy)] (pz= (pyrazol-1-yl)-borate and bipy = 2,2’-bipyridine) and [Fe(Htrz)2(trz)](BF4)] (Htrz = 1H-1,2,4-triazole) thin films . This conductance change is highly variable depending on the mechanism driving the change in spin state, the substrate and the device geometry. Simply stated, the choice of spin crossover complex used to build a device is not the only factor in determining the change in conductance with the change in spin state.

We demonstrate, in the context of Loop Quantum Gravity, the Quantum Holographic Principle, according to which the area of the boundary surface enclosing a region of space encodes a qubit per Planck unit. To this aim, we introduce fermion fields in the bulk, whose boundary surface is the two-dimensional sphere. The doubling of the fermionic degrees of freedom and the use of the Bogoliubov transformations lead to pairs of spin network’s edges piercing the boundary surface with double punctures, giving rise to pixels of area encoding a qubit. The proof is also valid in the case of a fuzzy sphere.

Results are presented concerning the influence on the water splitting process of enantiopure tartaric acid present in bulk solution. Stainless steel and electrodeposited nickel are used as working electrode (WE) surface. The latter is obtained by electrodeposition on the two poles of a magnet. The influence and role played by the chiral compound in solution has been assessed by comparing the current values, in cyclic voltammetry (CV) experiments, recorded in the potential range at which oxygen evolution reaction (OER) occurs. In the case of tartaric acid and nickel WE a spin polarization of about 4 % is found. The use of the chiral environment (bulk solution) and ferromagnetic chiral Ni electrode allows for observing the OER at a more favourable potential: about 50 mV (i.e. a cathodic, less positive, shift of the potential at which the oxygen evolution is observed).

We report the synthesis and characterization of Mn(III) chloride (MnIIICl3) complexes coordinated with N-oxide ylide ligands, namely trimethyl-N-oxide (Me3NO) and pyridine-N-oxide (PyNO). The compounds are reactive and, while isolable in the solid-state at room temperature, readily decompose into Mn(II). For example, “[MnIIICl3(ONMe3)n]” decomposes into the 2D polymeric network compound complex salt [MnII(µ-Cl)3MnII(µ-ONMe3)]n[MnII(µ-Cl)3]n•(Me3NO•HCl)n (4). The reaction of MnIIICl3 with PyNO forms varied Mn(III) compounds with PyNO coordination and these react with hexamethylbenzene (HMB) to form the chlorinated organic product 1-cloromethyl-2,3,4,5,6-pentamethylbenzene (8). In contrast to N-oxide coordination to Mn(III), the reaction between [MnIIICl3(OPPh3)2] and 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) resulted in electron transfer forming d5 manganate of the [TEMPO] cation instead of TEMPO–Mn(III) adducts. The reactivity affected by N-oxide coordination is discussed through comparisons with other L–MnIIICl3 complexes within the context of reduction potential.

The Katerini-Kolindros aquifer system (KKas) is a critical freshwater resource, essential for the local and regional economy. To understand contamination sources, groundwater flow paths, and assess the aquifer's health, an extensive dataset of 751 samples from 113 wells collected between 2010 and 2020 was analyzed using multivariate statistical analysis (MVSA) and hydrogeochemical diagrams. The prevailing water types identified were Ca-HCO₃ and Mg-HCO₃, with mixed water types resulting from various factors affecting groundwater quality. The chemistry of groundwater in the KKas is shown to be affected by ion exchange processes and to a lesser extent by reverse ion exchange processes. No indications of sea-water intrusion have been identified in the water wells monitored. On the other hand, nitrate contamination has been detected in specific water wells spatially associated with urban-type land uses and activities. It is considered that nitrate contamination originates primarily from septic tanks and urban sewage networks or secondarily from fertilization of football pitches, cemeteries or urban waste management practices.

Accurately predicting drug-drug interactions (DDIs) is crucial for preventing adverse drug events in clinical settings. However, existing methodologies often rely on complex models built from diverse data sources, posing challenges in computational drug discovery. To address the need for precise computational methods in predicting unknown DDIs, this study introduces a novel Deep Neural Network (DNN)-based approach. By leveraging a wide range of drug-related information, including substructure, targets, side effects, pathways, and indications, our method calculates multiple drug similarities. These similarities are then synthesized using a nonlinear fusion method to extract high-level features. Subsequently, a tailored neural network is deployed for interaction prediction. Comparative evaluation against three prominent machine learning classifiers—Extreme Gradient Boosting (XGBoost), Adaptive Gradient Boosting (AdaBoost), and Light Gradient-Boosting Machine (LGBM)—using three benchmark datasets demonstrates the superior performance of DNN. It achieves outstanding accuracy, precision, recall, and F1-score metrics, all reaching 94.6% in cross-validation. Additionally, case studies involving numerous drug pairs confirm the reliability of DNN in accurately predicting unknown DDIs. These findings underscore DNN as a potent and reliable method for DDI prediction, with promising implications for drug discovery and healthcare applications.

This study aimed to determine the correlation of colour M-mode velocity propagation in the assessment of left ventricular diastolic function among acute decompensated heart failure patients with preserved ejection fraction (HFpEF). This research is an observational analytical study using a cross–sectional study design conducted from April to June 2022. The subjects of this study were patients diagnosed with acute HFpEF and treated at Dr. Soetomo General Academic Hospital, Surabaya. Patients with heart rhythm disturbances, moderate to severe valvular heart disease, and congenital heart defects were excluded from this study. Patients were measured for diastolic function including mitral valve early mitral inflow velocity (MV E Velocity), mitral peak velocity of early filling (E’) (E' Septal and E' Lateral), left atrial volume index (LAVI), The maximal tricuspid regurgitation velocity (TR V Max), Vp, the ratio of early diastolic mitral inflow velocity to early diastolic mitral annulus velocity (E/E'), the ratio between early and late ventricular filling velocity (E/A) and E/Vp Ratio. N-terminal-pro hormone B-type natriuretic peptide (NT–ProBNP) examination was also performed on study subjects as an additional diagnosis of acute heart failure. There were 33 patients who met the inclusion and exclusion criteria and were included in our study. There were 26 patients (78.8%) with grade I diastolic dysfunction, 4 patients (12.1%) with grade II diastolic dysfunction, and 3 patients (9.1%) with grade III diastolic dysfunction. There is a strong positive correlation between Vp with parameters E' Septal (p = &lt; 0.001; r = 0.636) and E' Lateral (p = &lt; 0.001; r = 0.650). Vp is negatively correlated with the ratio E/E' (p = 0.029; r = –0.37). The PCWP estimate with E/Vp ratio had a strong correlation with the NT–Pro BNP value &gt; 300 pg/ml in acute HFpEF patients (p = &lt; 0.001; r = 0.726) compared to the PCWP estimate with E/E' (p = &lt; 0.001; r = 0.549). There is no correlation between Vp value and degree of diastolic dysfunction in patients with acute HFpEF.

Rational delineation of urban–rural boundaries is a foundational prerequisite for holistic urban and rural development planning and rational resource allocation. However, the results of division of urban–rural boundaries extracted using a single data source are non-comprehensive. To address this problem, the present study proposes a method for using multiple sources such as population data, nighttime light data, land use, and points of interest (POI) data to extract urban–rural boundaries. Considering Guizhou Province for a case study, we here present a two-step method for identifying urban–rural boundaries. First, the random forest model was combined with the dasymetric mapping method to obtain the population spatialization data with a 30-m resolution in the studied province. Second, using the breaking point method, we extracted the urban–rural boundary for Guizhou Province in 2020 based on the spatialized population. This method fully integrated the benefits of various data and judiciously extracted the boundaries of the main urban areas and small- and medium-sized towns of each city in the study province at the same spatial scale. The stratified random sampling method revealed that the average overall accuracy was 88.05%. The method proposed has certain universality and application value and allows identifying the urban–rural boundaries more accurately and practically.

Spin-orbit coupling and nonparaxiality effects during propagation of vortex vector light beams in a cylindrical graded-index waveguide are investigated by solving the full three-component field Maxwell’s equations. Symmetry breaking effects for left- and right-handed circularly polarized vortex light beams propagating in a rotationally symmetric graded-index optical fiber are considered. The mode-group delay in a graded-index fiber due to spin-orbit interaction is demonstrated. It is shown that the relative delay times between vortex pulses of opposite circular polarizations of the order of 10 ps/km can be observed in graded-index fibers for high-order topological charges.

Microfiltration membranes derived from semi-crystalline polymers face various challenges when synthesized through the extrusion–casting technique, including the use of large quantities of polymer, long casting times, and the generation of substantial waste. This study focuses on synthesizing these membranes using spin-casting followed by stretch-induced pore formation. Recycled high-density polyethylene (HDPE) and virgin polyethylene powder, combined with a calcium carbonate filler, were used as the source materials for the membranes. The influence of the polymer-filler ratio with and without stretching on the morphology, tensile strength, and water flow rate was investigated. Optimal conditions were determined, emphasizing a balance between pore structure and mechanical integrity. The permeable membrane possessed a mean pore diameter of 500 nm, exhibited a tensile strength measuring 32 MPa, allowed water to flow at a rate of 19 ml/min, and had a water contact angle of 126°. These membranes effectively eliminated suspended particles from water, with their performance evaluated against that of commercially available membranes. This research outlines a synthesis route for microfiltration membranes tailored to semi-crystalline polymers and their plastic forms, utilizing the spin-casting technique.

Quantum physics is intrinsically probabilistic. The entropy of a quantum state quantifies the amount of randomness (or information loss) of such state. The degrees of freedom of a quantum state are position and spin, and upon their specification Born's rule in phase space defines randomness. We focus on the spin degree of freedom and elucidate the spin entropy. Then, we present some of its properties and show how entanglement increases spin entropy. Some speculative predictions on the decay of the $Z^0,W^{+,-}$ gauge bosons conclude the paper.

The spin-1/2 quantum transverse Ising model, defined on a ladder structure, with nearest-neighbor and four-spin interaction on a plaquette, is studied by using exact diagonalization and finite-size-scaling procedures. The quantum phase transition between the ferromagnetic and paramagnetic phases has been obtained in the thermodynamic limit. The critical transverse field decreases as the antiferromagnetic four-spin interaction increases, and reaches a multicritical point. However, the exact diagonalization approach was not able to capture the essence of the dimer phase beyond the multicritical transition.

We propose an experimental method for the unidirectional excitation of spin waves. By structuring Au nanowires arrays within a coplanar waveguide onto a thin yttrium iron garnet (YIG) film, we observe a chiral coupling between the excitation field geometry of the nanowires grating and several well-resolved propagating magnon modes. We report a propagating spin wave spectroscopy study with unprecedented spectral definition, wavelengths down to 130 nm and attenuation lengths well above the 100 μm over the 20 GHz frequency band. The proposed experiment paves the way for future non-reciprocal magnonic devices.

1D spin crossover (SCO) solids which convert between the low-spin (LS) and the high-spin (HS) states are widely studied in the literature due to their diverse thermal and optical characters which allows obtaining many original behaviors, such as large thermal hysteresis, incomplete spin tran-sitions, as multi-step spin transitions with self-organized states. In the present work, we investigate the thermal behaviors of a system of two-elastically coupled 1D mononuclear chains, using the electro-elastic model, by including an elastic frustration in the nearest neighbors (nn) bond length distances of each chain. The chains are made of SCO sites that are coupled elastically through springs with their nn and next-nearest neighbors. The elastic inter-chain coupling includes diagonal springs, while the nn inter-chains distance is fixed to that of the high-spin state. The model is solved using MC simulations, performed on the spin states and the lattice distortions. When we only frustrate the first chain, we found a strong effect on the thermal-dependence of the HS fraction of the second chain, whose, by lowering its transition temperature which is also accompanied with the appearance of a significant residual HS fraction at low temperature. In the second step, we frustrate both chains by imposing different frustration rates and found that, for high frustration values, the thermal dependence of the total HS fraction exhibits three step and even four step spin transitions. The careful examination of the spin state structures in the plateau regions revealed the existence of special antiferro-elastic structure of type LSLS-HSHS-LSLS-HSHS along the first chain, and HSHS-LSLS-HSHS-LSLS along the second, also showing that the two chains seem to be antifer-ro-elastically coupled. This type of organization is interesting, because it anticipates the possible existence of periodic structures made of alternate 1D antiferro-like HS-LS strings coupled in the ferro-like fashion along the interchain direction in the 2D case.

We present the Lagrangian and Hamiltonian formulations of a theory for spin 2 fields. The construction is developed in flat space-time. The construction in curved space-time is conceptually straightforward, although it is not unique. The theory is based on a symmetric tensor $S_{\mu\nu}$, contains two degrees of freedom of radiation, is motivated by the teleparallel formulation of general relativity, and displays a certain resemblance with Maxwell's theory for the electromagnetic field.

Abstract: I present a generalization of quantum electrodynamics which includes Diracmagnetic monop oles and the Salam magnetic photon. This quantum electromagnetodynamics has many attractive features. (1) It explains the quantization of electric charge. (2) It describes symmetrized Maxwell equations. (3) It is manifestly covariant. (4) It describes local four-potentials. (5) It avoids the unphysical Dirac string. (6) It predicts a second kind of electromagnetic radiation which can be veried by a tabletop experiment. An eect of this radiation may have been observed by August Kundt in 1885. Furthermore I discuss a generalization of General Relativity which includes Cartan's torsion. I discuss the mathematical denition, concrete description, and physical meaning of Cartan's torsion. I argue that the electric-magnetic duality of quantum electromagnetodynamics is analogous to the spin-mass duality of Einstein-Cartan theory. A quantum version of this theory requires that the torsion tensor corresponds to a spin-3 boson called tordion which is shown to have a rest mass close to the Planck mass. Moreover I present an empirically satised fundamental equation of unied eld theory which includes the fundamental constants of electromagnetism and gravity. I conclude with the remark that the concepts presented here require neither Grand Unication nor supersymmetry.

The interest in random fiber lasers (RFLs), first demonstrated one decade ago, is still growing and their basic characteristics have been studied by several authors. RFLs are open systems that present instabilities in the intensity fluctuations due to the energy exchange among their non-orthogonal quasi-modes. In this work, we present a review of the recent investigations on the output characteristics of a continuous-wave erbium-doped RFL, with emphasis on the statistical behavior of the emitted intensity fluctuations. A progression from the Gaussian to Lévy and back to the Gaussian statistical regime was observed by increasing the excitation laser power from below to above the RFL threshold. By analyzing the RFL output intensity fluctuations, the probability density function of emission intensities was determined, and its correspondence with the experimental results was identified, enabling a clear demonstration of the analogy between the RFL phenomenon and the spin-glass phase transition. A replica-symmetry-breaking phase above the RFL threshold was characterized and the glassy behavior of the emitted light was established. We also discuss perspectives for future investigations on RFL systems.

The rationalization of single molecule magnets’ (SMMs) magnetic properties by quantum mechanical approaches represents a major task in the field of the Molecular Magnetism. The fundamental interpretative key of molecular magnetism is the phenomenological Spin Hamiltonian and the understanding of the role of its different terms by electronic structure calculations is expected to steer the rational design of new and more performing SMMs. This paper deals with the ab initio calculation of isotropic and anisotropic exchange contributions in the Fe(III) dimer [Fe₂(OCH₃)₂(dbm)₄]. This system represents the building block of one of the most studied Single Molecule Magnets ([Fe₄RC(CH₂O)₃)₂(dpm)₆] where R can be an aliphatic chain or a phenyl group just to name the most common functionalization groups) and its relatively reduced size allows the use of a high computational level of theory. Calculations were performed using CASSCF and NEVPT2 approaches on the X-ray geometry as assessment of the computational protocol, which has then be used to evinced the importance of the outer coordination shell nature through organic ligand modelization. Magneto-structural correlations as function of internal degrees of freedom for isotropic and anisotropic exchange contributions are also presented, outlining for the first time the extremely rapidly changing nature of the anisotropic exchange coupling.

The opportunistic pathogen Pseudomonas aeruginosa is responsible for numerous chronic infections and has a case fatality rate of 50%. All P. aeruginosa strains express β–lactamase, an enzyme capable of inactivating β–lactam antibiotics, including penicillins. However, β–lactams are still considered desirable therapeutics by physicians due to their low toxicity. The short-term goal of this study was to create an optimal model for ampC expression in P. aeruginosa and determine the selecting antibiotic to be used during mutagenesis. In the long term, this study aims to renew effectiveness of β–lactams by identifying potential allosteric binding sites on β–lactamase for the development of novel β–lactamase inhibitors. To create a system for ampC expression, the chromosomal P. aeruginosa ampC gene encoding for β–lactamase was cloned into Escherichia coli, then conjugated into P. aeruginosa ∆ampC. β– lactamase assays on recombinant E. coli and P. aeruginosa detected much higher production of β–lactamase in pMMB67HE, which was confirmed with antibiotic susceptibility testing (AST) to numerous β-lactams. From AST, carbenicillin was chosen as the antibiotic to select functional β–lactamase production during mutagenesis. Future work includes conducting mutagenesis on ampC to identify allosteric binding sites on the β–lactamase enzyme that may enable the discovery of new β–lactamase inhibitors. This work allows for the development of novel β–lactamase inhibitors that could renew the utility of β–lactams and drastically reduce morbidity and mortality from chronic Pseudomonas infections.

In two previous articles, the extended $(k, t)$--Fibonacci numbers were presented and some of their properties were studied, both in general and particularizing them for the Leonardo numbers. In a second article we study the sum of the extended $(k, t)$--Fibonacci numbers as well as the sums of these odd and even numbers.\\ In this article we study the sum of the squares of these numbers with their properties as well as the generating function, the recurrence relation and the Binet formula.\\ Finally we particularize these results for the generalized $t$--Leonardo numbers.

Background: A Morel–Lavallée lesion (MLL) is a traumatic, internal closed degloving injury that results from shearing of subcutaneous tissue away from underlying fascia, usually associated with high-velocity trauma. Case presentation: A 52-year-old man was transported to hospital for further follow-up of a superficial femoral artery injury. Examination on admission showed bruising seen around the left thigh. Contrast-enhanced computed tomography of the left thigh revealed hematoma with extravasation from a branch of the left superficial femoral artery, but no apparent aneurysms or femoral fractures. The patient was treated with compression bandages and discharged on hospital day 6. He left hospital able to walk unaided. He subsequently complained of left thigh pain with swelling and visited the hospital several times. He was treated at another outpatient clinic and was diagnosed with MLL. Single-use disposable portable negative pressure wound therapy (NPWT) was applied for about 2 months, achieving a stable wound site. Conclusion: We encountered a case of MLL successfully treated with single-use portable NPWT. This report presents the case of a patient with isolated MLL without fracture in the left thigh, in which the diagnosis was missed on initial admission. Finally, the patient received minor interventions including drainage along with tissue debridement and portable NPWT. We reviewed the relevant literature and summarize the pathogenesis, clinical manifestations, and treatment strategies for MLL. Emergency physicians require an increased understanding of MLL to avoid misdiagnosis and missed diagnosis.

Antibiotic beads were used to treat surgical infections. In this study, polylactide–polyglycolide (PLGA) was mixed with vancomycin, osteogenic enhancer lithium chloride (LiCl), and hot com-pressing to form PLGA-vancomycin-LiCl delivery beads to treat bone infection. An elution method was employed to characterize the in vitro release characteristics of the vancomycin and the Li over a 42-day period. The released profiles lasted for more than 42 days for vancomycin and 28 days for Li. The concentration of vancomycin in each sample was well above the breakpoint sensitivity. Lithium co-treatment enhanced the bactericidal effect of vancomycin. Released Li and vancomycin increased mRNA or protein expressions of osteogenic markers of mesenchymal stem cells (MSCs). In vivo, the PLGA delivery systems were implanted into the rabbit distal femoral cavities and the cavity fluid content was aspirated and analyzed at each time point. The released Li and vancomycin lasted more than 6 weeks, and vancomycin concentrations were much above the breakpoint sensitivity. Four rabbits in each group were killed at 8 weeks for histologic observation. More mature bone tissue was shown in the Li treatment group. This study provides a PLGA drug delivery system to meet the requirements of patients with bone infections.

Cardiovascular diseases are a broadly understood concept focusing on vascular and heart dys-function. Lack of physical exercise, type 2 diabetes, obesity, hypertension, dyslipidemia, throm-boembolism, kidney, and lung diseases all contribute to the development of heart and blood vessel dysfunction. Although effective and important, traditional treatment with diuretics, statins, beta–blockers, calcium inhibitors, ACE inhibitors, and anti–platelet drugs remain a second–line treatment after dietary intervention and lifestyle changes. Scientists worldwide are still looking for an herbal product that would be quite effective and free from side effects, either taken together or before the standard pharmacological intervention. Such herbal–originated medication therapy may include Morus alba L. (white mulberry), Elaeagnus rhamnoides (L.) A. Nelson (sea–buckthorn), Allium sativum L. (garlic), Convallaria majalis L. (lily of the valley), Leonurus cardiaca L. (mother-wort), and Crataegus spp. (hawthorn). Valuable herbal raw materials include leaves, fruits, seeds, and even thorns. This short review focuses on six herbs that can constitute an interesting and po-tential therapeutic option in the management of cardiovascular disorders.

In Caucasians, basal cell carcinoma, a type of non-melanoma skin cancer, is most often found on the nose. This presents challenges for surgeons due to anatomical, functional, and aesthetic concerns. The study aimed to evaluate the distribution of tumor localization, size, morphological subtypes, surgical outcomes, radicality levels, and their correlation with recurrence rates. The research utilized data from the Hygiene Institute Health Information Centre. A retrospective analysis encompassed 343 cases of nasal skin cancer over a four-year period from January 1, 2019, to December 31, 2022. The research cohort comprised 252 female and 91 male participants, averaging 75,2 years old. Tumors were most found on the left sidewall of the nose (25.4%) and the dorsum (24.8%). The infiltrative morphological subtype was predominant (70.8%). Standard surgical excision with fasciocutaneous plastic was the preferred surgical procedure. Radical excision was achieved in 79.0% of lesions, while 16.9% were incompletely excised. Non-radically excised tumors exhibited a significantly higher recurrence rate (24.1%) compared to those with radical excision (6.3%). In nasal reconstruction, diverse surgical techniques are essential for precise adaptation based on factors like tumor characteristics and patient needs. Despite surgeons' careful adherence to excision guidelines, the potential for non-radical procedures cannot be entirely eliminated.

Oxidative stress (OS) plays a crucial role in placental pathogenesis and pregnancy-related complications. This review explores OS's impact on placental development and function, focusing on novel biomarkers for early detection of at-risk pregnancies and emerging therapeutic strategies. We analyzed recent research on OS in placental pathophysiology, examining its sources, mechanisms, and effects. While trophoblast invasion under low-oxygen conditions and hypoxia-induced OS regulate physiological placental development, excessive OS can lead to complications like miscarriage, preeclampsia, and intrauterine growth restriction. Promising OS biomarkers, including malondialdehyde, 8-isoprostane, and the sFlt-1/PlGF ratio, show potential for early detection of pregnancy complications. Therapeutic strategies targeting OS, such as mitochondria-targeted antioxidants, Nrf2 activators, and gasotransmitter therapies, demonstrate encouraging preclinical results. However, clinical translation remains challenging. Future research should focus on validating these biomarkers in large-scale studies and developing personalized therapies to modulate placental OS. Emerging approaches like extracellular vesicle-based therapies and nanomedicine warrant further investigation for both diagnostic and therapeutic applications in pregnancy-related complications. Integrating OS biomarkers with other molecular and cellular markers offers improved potential for early identification of at-risk pregnancies.

We consider creation of entanglement between the remote electron spins using a magnetic nanoparticle attached to a cantilever tip (CT). We assume that the frequency of the CT vibrations matches the Larmor frequency of the spin (the CT-spin resonance). In the conditions of the CT-spin resonance the CT-spin system is described by the exactly solvable Jaynes-Kummings model. In this work using the evolution operator of the Jaynes-Kummings model we show that a movable CT can create an entangled state between the remote spins. The most striking result is that the entanglement between the remote spins can be achieved without measurement of the vibrational state of the CT.

A deterministic quantum mechanics theory is presented in a series of papers starting with the present one. The proposed theory is shown to be consistent with the current mainstream statistical quantum theory as well as with classical physics. It produces solutions, which demonstrate that causality, physical reality, and determinism are restored and can explain in simple form concerns that are raised by results from the current mainstream statistical quantum theory. The meaning of particle- wave duality and complementarity, the possibility of a particle, like the electron, to cross through the nucleus as it does when the angular momentum of the electron is zero at the ground state of the hydrogen atom, the possibility of a point-size particle to have an “intrinsic spin”, the possibility of “quantum jumps” as the electron transitions instantaneously from one stable orbital to another without passing through the space in between the orbitals and does that at irregular time intervals, and the natural collapse of the wave function as part of the solution are some of the results that emerge from the proposed deterministic quantum mechanics theory. The phenomenon of entanglement is shown to be consistent with the proposed deterministic quantum mechanics theory. The Bohr-Schrödinger energy levels leading to the experimentally confirmed spectral lines, as well as the fine structure constant emerge directly from the solution of the equations governing theproposed deterministic quantum mechanics presented in Part II of these series of papers.

This is the second paper in a series introducing a deterministic quantum mechanics theory that is shown to be consistent with the current mainstream statistical quantum theory as well as with classical physics. The first paper in this series demonstrated how causality, physical reality, and determinism are restored and concerns that were raised by results from the current mainstream statistical quantum theory were explained in simple form. The meaning of particle-wave duality and complementarity, the possibility of a particle, like the electron, to cross through the nucleus as it does when the angular momentum of the electron is zero, the possibility of a point-size particle to have an “intrinsic spin”, the possibility of “quantum jumps” as the electron transitions instantaneously from one stable orbital to another and does that at irregular time intervals, the natural collapse of the wave function as part of the solution, as well as consistency with the phenomenon of entanglement were some of the results that emerged from the proposed deterministic quantum mechanics theory. While the first paper presented overwhelming evidence of the latter, the present paper is the first to produce actual solutions that are consistent with current mainstream quantum theory as well as with classical physics. Analytical solutions are presented via a linear stability method. The Bohr-Schrödinger energy levels leading to the experimentally confirmed spectral lines, as well as the fine structure constant emerge directly from the solution of the equations governing the proposed deterministic quantum mechanics. Recommended follow-up solutions as well as generalizations are being presented at the end of the paper.

In this review, several cost-effective thin-film coating methods which include dip-coating, spin-coating, spray-coating, blade-coating, and roll-coating are presented. Each method has its set of advantages and disadvantages depending on the type of application. Not all of them are appropriate for large-scale production due to their certain limitations. That is why the coating method should be selected based on the type and size of substrate including the resolution of the required thin-films. The sol-gel method offers several benefits, such as simplicity in fabrication, excellent film uniformity, the capacity to cover surfaces of any size and over vast areas, and a low processing temperature. Nevertheless, these coating methods are somewhat economical and well managed in low-budget laboratories. Moreover, the produced thin-films are homogeneous and have low-surface roughness. Furthermore, some other thin-film deposition methods such as physical vapor deposition (PVD) and chemical vapor deposition (CVD) are also discussed. Since CVD is not restricted to line-of-sight deposition, a characteristic shared by sputtering, evaporation, and other PVD processes, many manufacturing methods favor it. However, these techniques require sophisticated equipment and cleanroom facility. We aim to provide the pros and cons of thin-film coating methods and let the readers decide the suitable technique for their specific application.

In this study, we propose a solution process for realizing color glass for building integrated pho-tovoltaic (BIPV) systems by spin coating a color solution composed of a pearlescent pigment mixed in a norland optical adhesive (NOA) matrix. Color solutions are made from mixing pearlescent pigments in NOA63. Compared to a physical vapor deposition process, color coatings are achieved by spin coating in a relatively simple and inexpensive process at room temperature. The optical properties can be easily controlled by adjusting the spin coating speed and the concentra-tion of the pearlescent pigments. The produced color glasses achieved a high transmittance of 85% or more in the visible wavelength range, except the wavelength spectrum exhibiting the maxi-mum reflectance. In addition, we propose a one-step lamination process of color glass on a solar cell by leveraging on the adhesive property of the NOA matrix. This eliminates the cost and pro-cess of additional ethylene vinyl acetate (EVA) layer or other materials used in the conventional lamination process. The color glass produced through this study has stability that does not change its properties over time. Therefore, it is expected to be applied to the BIPV solar module market where aesthetics and energy efficiency are required.

Reactions of Fe(II) with the tris-(pyridin-2-yl)ethoxymethane (py3C-OEt) tripodal ligand in presence of the pseudohalide ancillary NCE- (E = S, Se, BH3) ligands led to a series of three mononuclear complexes formulated as [Fe(py3C-OEt)2][Fe(py3C-OEt)(NCE)3]2·2CH3CN, with E = S (1), BH3 (2) and Se (3). Single crystal characterizations (complexes 1-2) and X-ray powder diffraction (complexes 1-3) reveal monomeric isomorph structures formed by the spin crossover (SCO) anionic [Fe(py3C-OEt)(NCE)3] complex, associated with the low spin (LS) cationic [Fe(py3C-OEt)2]2+ complex and two solvent acetonitrile molecules. In the [Fe(py3C-OEt)2]2+ cation, the Fe(II) is coordinated by two py3C-OEt tridentate ligands, while the [Fe(py3C-OEt)(NCE)3] anion displays a hexacoordinated environment involving three N-donor atoms of one py3C-OEt ligand and three nitrogen atoms arising from of the three (NCE) coligands. The magnetic studies show the presence of gradual SCO behavior for the three complexes: a one-step transition around 205 K for 1 and two step-transitions for compounds 2 and 3, centred at 245 K and 380 K for 2, and at 170 K and 298 K for 3. The magnetic behaviors of complexes 1 and 2 remain unchanged when heating up to 500 K, while complex 3 shows significant changes which are caused by the crystallisation solvent loss above room temperature.

Complex systems can be described as the network of interactions between their components. In directed networks, information, energy and matter flow in dominant directions. Undirected networks, on the other hand, cannot easily capture these asymmetries. The local flow of information depends on the node spin, which is a function of the number of incoming and outgoing links attached to it. And yet, how the heterogeneous association between in-degree and out-degree constraints global dynamics remains poorly understood. Here, we develop a new theoretical model to study the relationship between node directionality and global flow dynamics. Our computational analysis of random and scale-free directed networks indicates that structural diversity constrains the dimensionality of reachable dynamical space. These results suggest how local directionality might be an universal driver of global dynamics in many systems, from social networks, to technological systems to the connectome.

An analysis is presented of the possible existence of a second anomalous dipole moment of Dirac’s particle next to the angular one. It includes a discussion why, in spite of his own derivation, Dirac has doubted about its relevancy. It is shown why since then it has been overlooked and why it has vanished from leading textbooks. A critical survey is given on the reasons of its reject, including the failure of attempts to measure and the perceived violations of time reversal symmetry and chargeparity symmetry. It is emphasized that the anomalous electric dipole moment of the pointlike electron (AEDM) is fundamentally different from the quantum field type electric dipole moment of an electron (eEDM) as defined in the standard model of particle physics and that its measurement requires different instrumentation. A proposal has been described how to prove or disprove its existence by experiment. Moreover, by reference from literature, the possible impact is discussed in the nuclear domain and in the gravitational domain.

The structural, electronic and magnetochemical properties of the star-shaped polyoxopalladate [Pd₁₅O₁₀(SeO₃)₁₀]¹⁰⁻ (POPd) and its lanthanide functionalized derivatives have been investigated on the basis of density functional theory followed by a ligand field analysis using the Radial Effective Charge (REC) model. Our study predicts that heteroPOPd is a robust cryptand that enforces D_5h symmetry around the encapsulated Ln³⁺ centers. This rigid coordination environment favors interesting potential magnetic behavior in the Er and Ho derivatives, which may be of interest for molecular spintronics and quantum computing applications.

New conjugated 2,6-diphenylaniline-azulene co-oligomers of linear and branched structure were synthesized by the interaction of borylazulenes with diphenylaniline bromides under Suzu-ki-Miyaura cross-coupling conditions. The obtained diphenylaniline-azulene co-oligomers inten-sively absorb and emit visible light (410-700 nm region), in particular, exhibits strong emission in the green as well as orange range with maxima of 510 / 590 nm. It is shown that such properties appear as a result of the positive resonance exposure to ani-line fragments significantly rearranging the electronic structure of azulene, in particular, the lev-els and energy gaps of frontal HOMO - LUMO orbitals.

The demand for improved service in mobile networks is always increasing. That means signal transmission with higher capacity is required. To achieve that goal a combined optical and wireless link using double polarization multiplexing has been developed. A high quality signal transmission is achieved by applying high polarization extinction ratio. The new concept is validated by experiments varying the bit rate and fiber length. A signal with 12 Gbit/s bit rate was transmitted over a 25 km long combined link with about 1.10-8 bit error rate. That result is much better than the already published data which were measured on links transmitting information with 2.5 Gbit/s bit rate. The polarization multiplexing technique is very practical for capacity enhancement in a specific section of an existing optical fiber by inserting a new link into it without deploying a new fiber.

Recent studies releaved that the high production of reactive oxidative species due to exposure of fine or ultrafine particles are implicated in many chronical respiratory disorders. However, the poor standard of clinical data in sub-Saharan countries makes very difficult the assessment of knowledge of air pollution health impact in urban cities. Objective: the aim of this study was to evaluate distribution of respiratory disorders associated to exposure of air fine and ultrafine particles through changes of some oxidative stress biomarkers among motorbike drivers from two cities of Cameroon Methods: A cross-sectional survey using a standardized questionnaire was conducted in 2019 on 191 motorcycle drivers (MD) working in Douala and Dschang. Then, the activity of superoxide dismutase (SOD) and the level of malondialdehyde (MDA) were measured by colorimetric methods. The data of participants after clustered in Excel Microsoft were analysed and statistically compared using Spss 2.0 software. Results: The motorbike drivers recruited to both cities were aged from 21 to 40, with mean age of 29.93 (± 0.82). The distribution of respiratory disorders as running nose, cold, dry cough, chest discomfort, and breathlessness, was significantly increased among MD in Douala. According to results of biological assays, SOD and MDA, were significantly more increased among MD recruited in Douala, compared to those of Dschang. The change of these oxidative stress markers was significantly correlated with mobilization of neutrophils and Monocytes showing initiation and evolution of subjacent inflammatory reactions, and seemed to be significantly influenced by place of habitation of MD. Conclusion: Through this study it is confirmed the evidence of initiation and evolution of oxidative stress with long-term exposure to air fine or ultrafine particles among active people in Urban cities. Further studies should be conducted with more analysis to provide evidence cellular damage and dysfunction related to chronically exposure to fine air PM among active people in metropolitan of sub-Saharan Africa context.

Melting, solidification and viscosity properties of a multicomponent Fe-Cu-Nb-Mo-Si-B alloys with low aluminum addition up to 0.42 at.% Al were studied using an oscillating cup viscometer. It is shown that melting and solidification are divided into two stages with a knee point at 1461 K. The temperature dependences of the liquid fraction between the liquidus and solidus temperatures during melting and solidification are calculated. It has been proven that aluminum accelerates the processes of melting and solidification and leads to an increase in liquidus and solidus temperatures. In the liquid state at temperatures above 1700 K in an alloy with a low aluminum content, the activation energy of viscous flow increases. This growth was associated with the liquid – liquid structure transition caused by the formation of large clusters based on the metastable Fe23B6 phase. Aluminum atoms attract iron and boron atoms and contribute to the formation of clusters based on the Fe2AlB2 phase and metastable phases of a higher order.

The retrieval of tree height percentiles with satellite lidar waveforms over the mountainous ar-eas is greatly challenged due to slanted and rugged topographic relief of underlying ground. A novel algorithm is proposed to extract the height percentiles based on the target response waveform (TRW) that is resolved by using a Richardson–Lucy deconvolution algorithm with an adaptive iterative time. The height metrics of the energy percentiles of 25%, 50%, 75% and 95% for the cumulative TRW distribution are determined by their vertical distances relative to the ground elevation in this study. To validate the proposed algorithm, we select the received waveforms of the Global Ecosystem Dynamics Investigation (GEDI) lidar over the Pahvant Mountains of central Utah, USA. The results reveal that the resolved TRWs resemble closely to the actual target response waveforms from the coincident airborne lidar data, with the mean values of the coefficient of correlation, total bias and root mean square error (RMSE) taking val-ue of 0.92, 0.0813 and 0.0016. In addition, the accuracies of the derived height percentiles from the proposed algorithm have been greatly improved compared with the conventional Gaussian de-composition method and the slope-adaptive waveform metrics method. The RMSE values de-crease by the mean values of 1.96 m and 2.72 m, respectively. It demonstrates that the proposed algorithm has good potential in the extraction of forest structure parameter over rugged moun-tainous areas.

Alzheimer’s disease (AD) is a predominant and incurable chronic debilitating neuro-degenerative disorder occupying more than 60% of all types of dementias. It is inaugurating by a cascade of events initiating from amnesic-type memory impairment and by gradually loss of cognitive and executive capacities, which is an intolerable problem for the patients and their familiars. Pathologically, there is overwhelming evidence that clumps of misfolded amyloid-β (Aβ) and hyperphosphorylated Tau protein aggregate in the brain. These pathological processes leading to synapse loss, neuronal loss, brain atrophy and gliosis culminating in neurodegeneration and fuelling AD. Thus, at a basic level, abnormality in brain proteins function is observed, causing disruption in the brain network and loss of neural connectivity. Nevertheless, AD is a multifactorial disorder, caused by a combination of age-related changes, genetic, environmental and lifestyle factors that affect the brain over time, its mysterious pathology seems non limited to senile plaques (Aβ) and neurofibrillary tangles (tau), but plethora of substantial and biological processes have been also emerged in its pathogenesis such as — breakdown and/or dysfunction of the blood–brain barrier (BBB); patients’ carriers of the gene variant APOE4; and the immunosenescence of the immune system. Furthermore, type 2 diabetes (T2DM) and metabolic syndrome (MS) whose have also observed as early markers that may provoke pathogenic pathways that lead or aggravate AD progression and pathology. Notwithstanding, of various pathological pathways, there are numerous substantial AD features that require shedding light on, such as chronic neuroinflammation, decrease glucose utilization and energy metabolism as well as brain insulin resistance (IR). Herein, we come to broadened our understanding & to connect the dots of the multiple comorbidities and their cumulative impact that may have synergistic effects on BBB dysfunction and AD pathology. We shed light on the path-physiological modifications in the cerebral vasculature that may contribute to AD pathology and cognitive decline prior to clinically detectable changes in amyloid beta (Aβ) and tau pathology, diagnostic biomarkers of AD, neuroimmune involvement and the role of APOE4 allele and AD-IR pathogenic link - the shared genetics and metabolomics biomarkers between AD and IR disorders. Investment in the future researches brings us closer to know the pathogenesis of AD, and paves the way to build preventive and treatment strategy.

Aims: To investigate the road safety concerns associated with pet dogs in New Zealand. Methods: An online survey was developed and offered to New Zealanders via SurveyMonkey© from 8 January 2019 to 31 March 2019) using New Zealand residents aged ≥18 years. Questions about the demographics of respondents and their number of pet dogs along with those about dog transportation and dog roaming were asked. Results: Of 2744 respondents who completed the online survey, 1494 (65%) owned a dog. Of these, 1511 completed the question about how their dog or dogs travel in vehicles. Of these, 2 % (n = 29) let their dog sit on the driver's knee, and 12 % (n = 179) allowed their dog to sit on the passenger's knee. Only 7 % (n = 105) allowed the dog to roam free throughout the vehicle, while 44% (n = 663) allowed their dogs to roam free in the backseat area only and 19% (n = 280) put their dog in the boot/hatchback area. A minority of respondents (2%, n = 22) indicated they let their dog travel unrestrained on the deck of a ute or truck. Approximately half, 51% (n = 767) of the respondents, indicated that they restrained or crated their dogs in or on the vehicle. Respondents also expressed concerns about roaming dogs being a road safety hazard with the themes of responsible ownership, physical and psychological harm, and the dangers of rescue altruism emerging. Conclusions: Increased awareness about proper pet restraints during transportation and preventing dogs from roaming, especially near and on roads, is crucial to ensure traffic safety for humans and dogs.

The goal of this study is to create regression models estimating the daily Penman–Monteith reference evapotranspiration (PMR) using latitude–temperature data for the state of Sinaloa, Mexico. Daily series of minimum–maximum temperature (1979–2017) were obtained from seven weather stations in Sinaloa. The reference evapotranspiration was calculated by the methods of Penman–Monteith using empirical equations (PMC), Hargreaves (HAC), and PMR. Prior to calculating PMC, the incident solar radiation (SR) was calculated. From the Acaponeta station (2005–2008, 2011–2013 and 2015–2017), all complete observed variables were obtained: mean temperature, incident solar radiation (SRg), average relative humidity and average wind speed at a height of 10 m. The data from the eight weather stations were provided by the National Meteorological Service and the National Water Commission. The daily observed Penman–Monteith reference evapotranspiration (PMO) was calculated. For validation, three simple linear regressions (SLR) were applied: SR vs SRg, PMC vs PMO and PMR vs PMO. hypothesis tests were applied to each SLR: Pearson correlation (Pr) vs critical Pearson correlation (Pcr). All rP were significantly different from zero (&gt; |0.576|): SRg vs SR (Pr = 0.951), PMC vs PMO (Pr = 0.592), and PMR vs PMO (Pr = 0.625). This study provides new models that can motivate and support the design and implementation of intelligent irrigation in the state considered “the breadbasket of Mexico.”

Motor intention is a high-level brain function related to planning for movement. Although studies have shown that motor intentions can be decoded from brain signals before movement execution, it was unclear whether intentions relating to mental imagery of movement could be decoded. Here, we investigated whether differences in spatial and temporal patterns of brain activation were elicited by intentions to perform different types of motor imagery and whether the patterns could be used by a multivariate pattern classifier to detect such differential intentions. The results showed that it is possible to decode intentions before the onset of different types of motor imagery from functional MR signals obtained from fronto-parietal brain regions, such as the premotor cortex and posterior parietal cortex, while controlling for eye movements and for muscular activity of the hands. These results highlight the critical role played by the aforementioned brain regions in covert motor intentions. Moreover, they have substantial implications for rehabilitating patients with motor disabilities.

The PAX8/PPARγ rearrangement, producing the PAX8–PPARγ fusion protein (PPFP), is thought to play an essential role in the oncogenesis of thyroid follicular tumors. To identify PPFP-targeted drug candidates and establish an early standard of care for thyroid tumors, we performed ensemble docking-based compound screening. Specifically, we investigated which pocket structure should be adopted to search for a promising ligand compound for the PPFP; the position of the ligand binding pocket on the PPARγ side of the PPFP is common to that of PPARγ; however, the shape is slightly different between them due to environmental factors. We developed a method for selecting a PPFP structure with a relevant pocket and high prediction accuracy for ligand binding. This method was validated using PPARγ, whose structure and activity values are known for many compounds. Then, we performed docking calculations to PPFP for 97 drug or drug-like compounds with a thiazolidine backbone, which is one of the characteristics of ligands that bind well to PPARγ, registered in the DrugBank database. Furthermore, the binding affinities of promising ligand candidates were estimated more reliably using the molecular mechanics-Poisson–Boltzmann surface area method. Thus, we propose promising drug candidates for the PPFP with a thiazolidine backbone.

The South Asian economy is on the rise but struggling with power shortages and heavy dependence on fossil fuels. For sustained growth, there is a need for access to readily available energy sources, such as electricity. Trading clean electrical energy among neighbouring countries can ensure access to readily available points. South Asia has a diverse range of energy sources, including hydropower, that are available in the region. However, sectorial barriers can impede energy trading. This study has attempted to assess the readiness and barriers to Nepal’s cross-border energy trade with India and Bangladesh using the Analytic Hierarchy Process (AHP). This study also recommends possible measures to strengthen preparedness and address the challenges in energy trade that can be tailored and applied to other cross-country situations.

The nEDM experiment at Oak Ridge’s Spallation Neutron Source will probe for an electric dipole moment of the neutron at an unprecedented level of sensitivity. Polarized 3He atoms dressed by a radio-frequency field are a crucial component. For field parameters comparable to the parameters being used in the nEDM experiment, numerical studies using a fourth-order Runge-Kutta solver reveal inadequacies in earlier analyses of 3He spin dynamics. It’s seen that neutron absorption is influenced by avoided level-crossings omitted previously. Also, the critical dressing condition, used to eliminate effects of the static magnetic field, requires modification. First-order perturbative corrections to eigenstates and third-order corrections to eigenenergies are needed to account for the impact of avoided level-crossings and the changes in the critical dressing condition, respectively.

A topological representation theory of chiral spin liquid is proposed to unify the integral and fractional quantum Hall fluid based on hyperbolic geometry, knot lattice and Thurston's train track theory. The integral and fractional Hall resistivity obeys an exact unified equation, $R_{xy} = (h/e^2)B_{e}$, $B_{e} = (n+\nu)^{-1}$, with respect to the bulk energy gap ${\Delta}E = {\hbar{e}B_{e}}/{Mc}$. The Wen-Zee matrix formulation of topological fluid for quantum Hall effect is constructed by topological surgery and train track. The chirality of spin liquid is spontaneously distinguished by Jones polynomial. The integral Chern number for Hall conductance is fractionalized by generalizing Thurston's train track to folding laminations in three dimensions, which spontaneously bring fractional quantum Hall fluid and anyons into three dimensions and provided an theoretical explanation on the competing fractional quantum Hall states. The many body system of interacting fermions or bosons are mapped into many interacting liquid droplets that interwind into knot lattice, which provide an effective topological representation for superfluid and superconductor, the strange metal state in superconductor is explained by topological dislocation and topological surgery. The Kauffman decomposition rule in knot theory is extended to describe the topological relations between different two dimensional manifolds, which further reveals the non-trivial relationship between the partition functions of pairing fermions and free electrons. The minimal energy state is the most stable topological state, even thought it maybe shares the same topological number with the excited states. The topological representation theory predicts a circular motion of electrons in hyperbolic space, that is implementable and testable by inhomogeneous magnetic field in three dimensions. The folding lamination representation of topological quantum fluid provides an promising implementation of string theory in high energy physics.

{We present a statistical simulation replicating the correlation observed in EPR coincidence experiments without needing non-local connectivity. We define spin coherence as a spin attribute that complements polarization by being anti-symmetric and generating helicity. Point particle spin becomes structured with two orthogonal magnetic moments, each with a spin of $\frac{1}{2}$—these moments couple in free flight to create a spin-1 boson. Depending on its orientation in the field, when it encounters a filter, it either decouples into two independent fermion spins of $\frac{1}{2}$, or it remains a boson and precesses without decoupling. The only variable in this study is the angle that orients a spin on the Bloch sphere, first identified in the 1920s. There are no hidden variables. The new features introduced in this work result from changing the spin symmetry from SU(2) to the quaternion group, $Q_8$, which complexifies the Dirac field. The transition from a free-flight boson to a measured fermion is the reason for the observed violation of Bell's Inequalities and resolves the EPR paradox.

Under the quaternion group, $Q_8$, spin helicity emerges as an element of reality, and complementary to spin polarization. Here we show that the correlation in EPR coincidence experiments is conserved upon separation from a singlet, being divided between polarization and coherence. Including helicity accounts for the violation of Bell's Inequalities without non-locality.

Helical (frontier) molecular orbitals [Chem. Sci. 2013, 4, 4278] have been reported almost a decade ago. Yet, helical molecular spin densities [Mol. Phys. 2022, e2157774] have been observed by us only very recently. In this work, we have observed that some chiral boron clusters (B–16, B–20, B–24, and B–28) can simultaneously have helical molecular orbitals and helical spin densities. To our best knowledge, it is the first time we have discovered that inorganic boron clusters assume such an unprecedented property. We have unambiguously unraveled that it is chiral Jahn-Teller distortion of quasi-planar boron clusters that drives the formation of helical molecular spin densities. More interestingly, we have shown that elongation/enhancement of helical molecular orbitals can be achieved by simply adding more building blocks via a linker. Aromaticity properties of these boron clusters are also discussed. Implication of this work is straightforward that boron clusters may find potential applications in spintronics, such as molecular magnets.

We present an analysis of the Dirac equation when the spin symmetry is changed from SU(2) to the quaternion group, $Q_8$, afforded by multiplying one of the $\gamma$-matrices by the imaginary number. The reason for doing this is to introduce a bivector into the spin algebra. This complexifies the Dirac field which separates into two distinct and complementary spaces: one describing polarization and the other coherence. The former describes a 2D structured spin and the latter its helicity, generated by a unit quaternion.

Spin valves with a synthetic antiferromagnet were fabricated by magnetron sputtering. It was shown that the fabricated spin valves had perfect microstructure of layers and smooth interfaces, therefore RKKY interaction dominates in coupling of ferromagnetic layers separated by a copper spacer. Rhombus-shaped microobjects were fabricated from a single spin valve film. The thermomagnetic treatment procedure was found, to form unidirectional anisotropy in the microobject so, that the values of the exchange bias fields in the rhombus’ nonparallel sides were opposite in sign. For the synthetic antiferromagnet CoFeNi/Ru/CoFeNi the difference between ferromagnetic layers thicknesses was found, at which the thermomagnetic treatment forms the same exchange bias all over the rhombus’ side. The sensor element was fabricated in which each side of the rhombus was a shoulder of a Wheatstone bridge. After the thermomagnetic treatment procedure each shoulder worked as an active magnetosensitive element, thus the device operated as the full Wheatstone bridge. The sensor output has the shape of a step, high sensitivity to field change and significant magnetic hysteresis. Such characteristics are suitable for switching devices.

A high perovskite activity is sought for use in magnetic applications. In this paper, we present the simple synthesis of (2.5 and 5%) Tellurium-impregnated-LaCoO3 (Te-LCO), Te and LaCoO3 (LCO) by using a ball mill, chemical reduction, and hydrothermal synthesis, respectively. We also explored the structure stability along with the magnetic properties of Te-LCO. Te has a rhombohedral crystal structure, whereas Te-LCO has a hexagonal crystal system. The reconstructed Te was imbued with LCO that was produced by hydrothermal synthesis; as the concentration of the imbuing agent grew, the material became magnetically preferred. According to the X-ray photoelectron spectra, the oxidation state of the cobaltite is one that is magnetically advantageous. As a result of the fact that the creation of oxygen-deficient perovskites has been shown to influence the mixed (Te4+/2-) valence state of the incorporated samples, it is abundantly obvious that this process is of utmost significance. The TEM image confirms the inclusion of Te in LCO. The samples start out in a paramagnetic state (LCO), but when Te is added to the mixture, the magnetic state shifts to a weak ferromagnetic one. It is at this point that hysteresis occurs due to the presence of Te. Despite being doped with Mn in our prior study, rhombohedral LCO retains its paramagnetic characteristic at room temperature (RT). As a result, the purpose of this study was to determine the impacts of RT field dependency of magnetization (M-H) for Te-impregnated LCO in order to improve the magnetic properties of RT because it is a low-cost material for advanced multi-functional and energy applications.

Academic and corporate research has been focusing on analyzing stock performances, financial markets, and investment strategies for decades. According to Lynch and Rothchild (1989), certain investments can be described as plays. In this work, the authors use the term for investments in value stocks, spin-offs, and turnarounds to analyze the long-term stock performance and risk-adjusted excess returns of up to five years for those stocks. Additionally, stocks with a supe-rior return performance are identified within an investment play based on low P/E and P/B mul-tiples. The study finds that value stocks, spin-offs, and turnarounds outperform the S&P 500 on average on a one-, three- and five-year investment horizon. The analysis of the three investment plays confirms earlier studies that investment plays constitute a profitable investment opportunity. Moreover, the research exemplifies that private investors could achieve an excess return (alpha) through a passive buy-and-hold investment strategy. Overall, the analysis provides a deeper in-sight into the long-term performance of value stocks, spin-offs, and turnarounds.

NMR spin relaxation times have been an instrumental tool in deciphering the local en-vironment of ionic species, the various interactions they engender and the effect of these interactions on their dynamics in conducting media. Of particular importance has been their application in studying the wide range of electrolytes for energy storage, on which this chapter is based. Here we highlight some of the research carried out on electrolytes in recent years using NMR relaxometry techniques. Specifically, studies on liquid electro-lytes, such as ionic liquids and organic solvent; on semi-solid-state electrolytes, such as ionogels and polymer gels, and solid electrolytes such as glasses, glass ceramics and polymers. Although this chapter focuses on a small selection of materials, we believe they demonstrate the breadth of application and the invaluable nature of NMR relaxometry.

The coordination polymer [Fe(NH₂trz)₃](2ns)₂ exhibits the rare phenomenon of spin crossover in an attractive temperature range, i.e., somewhat above room temperature. Spin crossover in [Fe(NH₂trz)₃](2ns)₂ is manifest by thermochromism, which is accompanied by a magnetic transition from diamagnetism to paramagnetism. However, [Fe(NH₂trz)₃](2ns)₂ is brittle and difficult to process, which limits its use. In this study, we show that [Fe(NH₂trz)₃](2ns)₂ can be co-processed with ultrahigh molecular weight polyethylene (UHMWPE), which possesses outstanding mechanical properties, particularly when tensile drawn. Therefore, [Fe(NH₂trz)₃](2ns)₂–UHMWPE blends were gel-processed by extrusion, employing a relatively poor solvent, which has recently been shown to offer advantages compared to good solvents. Uniform and flexible films, ribbons and fibers with [Fe(NH₂trz)₃](2ns)₂ fractions as high as 33.3% m/m were obtained that could be readily drawn. Spin crossover in the coordination polymer is retained in these materials, as evident from their thermochromism. The tensile strength and Young’s modulus of the blends exceed those of typical commodity polymers. Thus, the films, ribbons and fibers constitute a special class of multifunctional materials that combine the flexibility and excellent mechanical properties of drawn UHMWPE with the spin crossover behavior of [Fe(NH₂trz)₃](2ns)₂.

Purpose: A number of imaging readout schemes have been proposed for renal arterial spin labelling (ASL) to quantify kidney cortex perfusion, including gradient echo based methods of balanced fast field echo (bFFE) and gradient-echo echo-planar imaging (GE-EPI), or spin echo based schemes of spin-echo echo planar imaging (SE-EPI) and turbo spin-echo (TSE). Here, we compare these imaging schemes to evaluate the optimal imaging scheme for pulsed ASL (PASL) assessment of human kidney cortex perfusion at 3 T. Methods: Ten healthy volunteers with normal renal function were scanned using each 2D multislice imaging scheme, in combination with a respiratory triggered FAIR (flow-sensitive alternating inversion recovery) ASL scheme on a 3 T Philips Achieva scanner. All volunteers returned for a second identical scan session within two weeks of the first scan session. Comparisons were made between the imaging schemes in terms of perfusion weighted image (PWI) signal-to-noise ratio (SNR) and perfusion quantification, temporal SNR (tSNR), spatial coverage, and repeatability. Results: For each imaging scheme, renal cortex perfusion was calculated (bFFE: 276 ± 29 mL/100 g/min, GE-EPI: 222 ± 18 mL/100 g/min, SE-EPI: 201 ± 36 mL/100 g/min, TSE: 200 ± 20 mL/100 g/min). Perfusion was found to be higher for GE based readouts compared to SE based readouts, with significantly higher measured perfusion for the bFFE readout compared to all other schemes (P < 0.05), attributed to the greater vascular signal present. Despite the PWI-SNR being significantly lower for SE-EPI compared to all other schemes (P < 0.05), the SE-EPI readout gave the highest tSNR and was found to be the most reproducible scheme for the assessment of kidney cortex, with a CoV of 17.2%, whilst minimizing variability of the perfusion weighted signal across slices for whole kidney perfusion assessment. Conclusion: For the assessment of kidney cortex perfusion, SE-EPI provides optimal tSNR, minimal variability across slices and repeatable data acquired in a short scan time with low specific absorption rate.

Molecular cages have promising host-guest properties for drug delivery applications. Specifically, guest⊂cage complexes can be used for on-command release of encapsulated guest molecules in response to specific stimuli. This research explores both dynamic and constrictive binding guest⊂cage systems for drug encapsulation and release in biological environments. In dynamic systems, the guest rapidly passes in and out through the portals of the cage, enabling drug delivery in vitro but facing limitations in vivo due to dilution effects that result in guest release. These challenges are addressed by constrictive binding systems, where the guest is trapped in a "gate-closed" state within the cage. In these systems, the on-command release is triggered by a "gate opening" event, which lowers the guest-out energy barrier. The full guest release is achieved when gate opening reduces the cage-guest affinity, making constrictive binding systems more effective for controlled drug delivery. As a result, this study shows that guest⊂cage complexes have suitable properties for drug delivery in biological contexts.

In this work, an attempt is made to the theoretically substantiate the experimentally known facts of the influence of halogen concentration on the catalytic properties of the neodymium-based Ziegler–Natta system. Based on the structural and thermochemical data obtained using modern methods of quantum chemistry, the process of the 1,3-butadiene cis-1,4-polymerization under the model active centers of the neodymium Ziegler-Natta catalysts with different content of chloride ions was studied. Results are presented that explain the increase in the cis-stereospecificity and activity of the polymerization system with an increase in the content of the chloride ions in the neodymium catalytic system. There were established the reasons for the decrease in the concentration of active centers relative to the introduced Nd(III) with an excess of chloride ions and the occurrence of the anti-syn isomerization as a source of the formation of the trans-1,4-structures in the cis-1,4-polybutadiene.