Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Descriptive Analysis of Routine Laboratory Testing for Neuraxial Blocks: A Real-world Retrospective Study

Version 1 : Received: 24 September 2024 / Approved: 24 September 2024 / Online: 25 September 2024 (17:54:04 CEST)

How to cite: Moon, S. H.; Oh, D. Descriptive Analysis of Routine Laboratory Testing for Neuraxial Blocks: A Real-world Retrospective Study. Preprints 2024, 2024091946. https://doi.org/10.20944/preprints202409.1946.v1 Moon, S. H.; Oh, D. Descriptive Analysis of Routine Laboratory Testing for Neuraxial Blocks: A Real-world Retrospective Study. Preprints 2024, 2024091946. https://doi.org/10.20944/preprints202409.1946.v1

Abstract

Background/Objectives: The necessity and clinical utility of routine pre-procedural blood tests (PBTs) before neuraxial blockade remain controversial. This study evaluates the effectiveness of PBTs in identifying clinically significant conditions in an outpatient setting. Methods: This single-center retrospective study involved patients who received neuraxial blockade from January 2020 to August 2023. We extracted medical information and laboratory data from the electronic medical records during the pre-procedural period. Through multivariate regression analysis, we identified patient factors associated with abnormal laboratory results. Results: Advanced age (OR, 1.021; p = 0.026) and a history of cancer (OR, 2.359; p = 0.016) were significantly associated with elevated CRP levels (>0.30 mg/dL). Severe hyperglycemia (≥200 mg/dL) was found in 24 patients (3.88%), with a history of cancer being a strong predictor (OR, 6.764; p < 0.001). No significant abnormalities were observed in PT or PTT. Reduced eGFR (

Keywords

neuraxial Blockade; blood tests; comorbidity; preoperative; pain management; glucose

Subject

Medicine and Pharmacology, Anesthesiology and Pain Medicine

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