Version 1
: Received: 4 April 2024 / Approved: 7 April 2024 / Online: 7 April 2024 (10:34:52 CEST)
How to cite:
Roșca, I.; Popescu, D.-E.; Jura, A. M. C.; Turenschi, A.; Filip, C.; Dinulescu, A.; Constantin, A. T. From Detection to Action: A Retrospective Analysis on the Impact of Screening for Congenital Heart Disease in the NICU. Preprints2024, 2024040470. https://doi.org/10.20944/preprints202404.0470.v1
Roșca, I.; Popescu, D.-E.; Jura, A. M. C.; Turenschi, A.; Filip, C.; Dinulescu, A.; Constantin, A. T. From Detection to Action: A Retrospective Analysis on the Impact of Screening for Congenital Heart Disease in the NICU. Preprints 2024, 2024040470. https://doi.org/10.20944/preprints202404.0470.v1
Roșca, I.; Popescu, D.-E.; Jura, A. M. C.; Turenschi, A.; Filip, C.; Dinulescu, A.; Constantin, A. T. From Detection to Action: A Retrospective Analysis on the Impact of Screening for Congenital Heart Disease in the NICU. Preprints2024, 2024040470. https://doi.org/10.20944/preprints202404.0470.v1
APA Style
Roșca, I., Popescu, D. E., Jura, A. M. C., Turenschi, A., Filip, C., Dinulescu, A., & Constantin, A. T. (2024). From Detection to Action: A Retrospective Analysis on the Impact of Screening for Congenital Heart Disease in the NICU. Preprints. https://doi.org/10.20944/preprints202404.0470.v1
Chicago/Turabian Style
Roșca, I., Alexandru Dinulescu and Andreea Teodora Constantin. 2024 "From Detection to Action: A Retrospective Analysis on the Impact of Screening for Congenital Heart Disease in the NICU" Preprints. https://doi.org/10.20944/preprints202404.0470.v1
Abstract
Congenital heart disease (CHD) is a prevalent congenital disorder diagnosed with high frequency, affecting approximately 0.8% to 1.2% of all live births. Research has demonstrated that the use of pulse oximetry and clinical examination as a screening tool for CHD diagnosis has proven extremely valuable. We conducted a retrospective longitudinal study over a 3-year period that involved screening 1188 newborns admitted to the NICU during the first 72 hours of life within this timeframe. 201 newborns were diagnosed with CHD. Almost all (n=198) had a positive screening test during the 72-hour period, while 3 had a negative screening test, but were later diagnosed using echocardiography. The prevalence rate was 16.67%. A confusion matrix was constructed with 198 true positives (TP), 3 false negatives (FN), no false positives (FP), and 987 true negatives (TN). The sensitivity of the screening test was 98.51%, while the specificity 100%, with no false positives. In our study, a total of 9 deaths occurred. Using the Kaplan-Meier method, the survival probability appeared to be slightly above 0.9 (95.5%), indicating that almost all patients survived past 72 hours after being diagnosed with CHD. Pulse oximetry is an effective, low cost and easy-to-use method and a useful tool to assess and lead to the diagnosis of CHD.
Medicine and Pharmacology, Pediatrics, Perinatology and Child Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.