Giannini, G.; Ragusa, I.; Nardone, G.N.; Soldi, S.; Elli, M.; Valenti, P.; Rosa, L. Tau-Marin Mucoadhesive Gel for Prevention and Treatment of Gum Diseases. Gels2023, 9, 607.
Giannini, G.; Ragusa, I.; Nardone, G.N.; Soldi, S.; Elli, M.; Valenti, P.; Rosa, L. Tau-Marin Mucoadhesive Gel for Prevention and Treatment of Gum Diseases. Gels 2023, 9, 607.
Giannini, G.; Ragusa, I.; Nardone, G.N.; Soldi, S.; Elli, M.; Valenti, P.; Rosa, L. Tau-Marin Mucoadhesive Gel for Prevention and Treatment of Gum Diseases. Gels2023, 9, 607.
Giannini, G.; Ragusa, I.; Nardone, G.N.; Soldi, S.; Elli, M.; Valenti, P.; Rosa, L. Tau-Marin Mucoadhesive Gel for Prevention and Treatment of Gum Diseases. Gels 2023, 9, 607.
Abstract
: An innovative and stable probiotics-containing mucoadhesive gel (AL0020), integrated with botanical extracts, has been developed to rebalance the dysbiosis associated with periodontal diseases. Tau-Marin gel was tested against some pathogenic bacteria, belonging to the so-called "red complex", recognized as the most important pathogens in plaque specimens, adherent to the epithelial lining of periodontal pockets. A detailed physico-chemical profile of AL0020 and its in vitro efficacy in protecting activity against pathogenic bacteria as well as soothing or irritative effect on gingival epithelium were reported. Moreover, a clinical-dermatological trial on 20 volunteers using the product once a day for 30 days was also performed.
Medicine and Pharmacology, Dentistry and Oral Surgery
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