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MMR vaccines may not always give lifelong immunity against measles

The level of protection against measles provided by the combined measles, mumps and rubella vaccine falls by a small amount every year, but remains high overall, according to mathematical modelling

By Clare Wilson

2 May 2024

Falling uptake of the MMR vaccines has led to a resurgence of measles in countries such as the UK

angellodeco/Shutterstock

Receiving two vaccine doses against measles as a child may not always lead to lifelong immunity, despite what is commonly thought, according to a modelling study. Even so, this remains the best way to safeguard against the illness.

The level of protection seems to fall by a very small amount per year, which could explain why a growing number of people are catching measles despite having had two vaccines against it in childhood. However, the shots are still 97…

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