Nikesh Parekh

Instacart is a market leader when it comes to leveraging AI tools to boost productivity at work. I had an amazing conversation with JJ Zhuang, Instacart’s Chief Architect, who has shepherded over 50 AI-driven initiatives to market across the org. We explored what catapulted Instacart to the forefront of AI integration, supporting radically diverse use cases across various functional areas. One striking insight (echoed by Ethan Mollick and others elsewhere) is that you often don't need specialized tools for specialized work. Frontier models like GPT-4 can seamlessly adapt to a wide range of functions and use cases. They're not just for engineers; they're incredibly versatile tools used by marketing, comms, and legal teams. From generating code to proofreading and ideation, GPT-4 empowers every department to leverage AI for enhanced productivity and innovation. By integrating LLM’s like GPT-4 into their workflows, teams can streamline processes, automate repetitive tasks, and unlock bandwidth for new creative possibilities. How can you harness the power of AI in your own work to boost productivity? Share your thoughts below 👇 Want to hear more insights from JJ? Check out the full podcast episode by clicking the link in the comments.

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🏢 Big Moves in SF Commercial Real Estate! Intuit & Capital One 🏢 Two major financial firms are making strategic relocations within San Francisco: - Capital One is reducing its office space by two-thirds, moving from 201 3rd St. to 40,000 sq. ft. at 100 California St. This deal includes significant improvements to the new location, enhancing tenant experiences with new outdoor spaces and on-site amenities. - Intuit is downsizing from 200,000 sq. ft. at 22 4th St. to 36,500 sq. ft. at 505 Howard St. The move aims to leverage San Francisco's diverse talent pool while optimizing their workspace for future growth. These moves highlight the dynamic nature of SF's commercial real estate market and the need for adaptable, strategic office solutions. At Resource, we specialize in guiding companies through such transitions, ensuring seamless relocations and optimized space utilization. 🔗 Discover more about our tailored real estate services: yourresource.com #SFRealEstate #CommercialRealEstate #CapitalOne #Intuit #OfficeRelocation #RealEstateStrategy #ResourceCRE

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Another great example of Seattle's tech ecosystem attracting investment, promoting growth, and potentially freeing up talent to either start their own new firms or attract new employers to enter the market to hire them. Transactions like this are part of the reason why Seattle remains one of the fastest growing regions in the country. #SeattleTech #TechInvestment #GrowthOpportunities #RealEstate

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Open-source models can be a strong lever for increasing gross margins at AI companies, especially those that have hefty cost structures (e.g., enterprise sales orgs that require significant customer success or implementation resources, as well forward-deployed AI services models common in healthcare and life sciences). One of many reasons to maintain a modular and flexible stack with minimal dependencies when building an AI company. More on the importance of flexibility in the AI stack: https://lnkd.in/eA2XATRk h/t Delip Rao #ai #artificialintelligence #generativeai #healthcare

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Excited to share a new report from our Insight IGNITE team (with contributions from yours truly :) As the business value of AI increases, so does the business risk... Insight Partners’ 2024 State of Enterprise Tech report identified AI as the top concern (and opportunity!) among cybersecurity leaders, including securing data used in AI systems and AI system access controls. Whether you're a cyber entrepreneur looking to learn more about enterprise priorities, or an enterprise leader looking for benchmarks for your current and future cyber strategy, this report has answers!

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Of note: Your health records are coming to new apps This in an interesting change, and a somewhat Epic change. All puns intended. If you don’t know, the leading medical record storage solution in the US is operated by Epic. A rather critical problem is that if you walk (well drive) between two hospital in the US, the medical records tend not to follow you, unless you carry a large Manila envelope. Having Epic (and others) via TEFCA allow export of records arguably allows you to only carry your phone, which is a very siginificant change. This also (arguably) opens up a huge new innovation sector. Epic is one of the organizations that has been helping the US federal government establish the Trusted Exchange Framework and Common Agreement, or TEFCA. The goal being to iron out both the legal and technical requirements for sharing patients' data at scale. Health-care data in the U.S. has historically been siloed and difficult to move around. Clinics, hospitals and health systems can store their information in a variety of formats across dozens of different vendors, and there hasn't been a trusted nationwide mechanism in place for transporting it securely. This means if a patient moves to a different state or visits a new hospital, their medical records tend not follow. PS. If you want appreciate how profitable the US medical sector is, Epic HQ has a restantant designed to look like Kings Cross from the Harry Potter movies. https://lnkd.in/g8NaWza8

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In 2013, Lori Torres felt an undeniable spark when she conceived the idea for Parcel Pending, a smart locker solution designed to tackle the package crisis in apartment buildings. Despite being the primary breadwinner in her family with a thriving real estate career, she took a monumental risk. She left her secure job, sold the family’s cherished home, and even persuaded her mother to risk her property for a loan. Within a year of these sacrifices, Lori had developed her first smart lockers. Her innovation soon caught on, with her lockers becoming a key solution for property management companies and residents. By the end of 2014, Lori’s commitment had not only secured her first major order but also attracted investors, setting the stage for tremendous growth. Within six years, Parcel Pending was sold for $100 million, turning her mother’s loan into a $1 million return and ensuring her family's future. Lori’s story highlights a key lesson for anyone seeking investors: truly committing to your vision can make a world of difference. By investing your own resources and security, you show investors just how dedicated you are to your idea. When you put everything on the line, it not only proves your commitment but also makes a strong case to potential backers. If you’re all in, it’s far easier to convince others to believe in your dream, and it could be the turning point in making it a reality. Are you prepared to go all in on your entrepreneurial dreams? Grab a copy of my book, “Thinking Bigger”, at the link below to read my personal experience chasing my dream and the advice I would share to anyone starting today. https://lnkd.in/dZpQYX6D #Entrepreneurship #WomenInBusiness #Startups #Investment #ThinkBigger

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Someone broke down the estimated costs of a $15 Sweetgreen salad. We need these cost graphics for digital health to help future founders. Especially for tech enabled cos, the greatest cost is labor. Much of the "value created" is in curation and matching, which means the gross margins are reliant on labor arbitrage. Pay someone $X, but get paid $X+Y% per visit. The challenge with healthcare is that you often have to pick one of two business models: 1. specialized, low volume, high cost, low gross margin % 2. generalized, high volume, low cost, high gross margin % I'd argue founders should focus on gross dollars over the lifetime of the customer (like Jeff Bezos said) instead of gross margin %'s, but we'll leave that for another time. The challenge is that many tech enabled digital health cos have high cost of goods sold (labor) and moderately high product, design, and engineering budgets. We must build differentiated solutions for patients, clinicians, and clients to be out incumbents, however, we're realizing that companies are ultimately valued on the discounted value of future cash flows. And the high SG&A costs at most organizations might be inbalanced to the unit economics of the business. I'm not sure the math pencils out for everyone unfortunately. But I'm just a guy on the internet, would love to hear the thoughts from those smarter than I (you!). Comment below. --- p.s. I have no idea the accuracy of the graphic and not an investor in Sweetgreen. Cheers. Credit: David Crowther

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Should you sell your practice to a VC-Backed MSO Startup? tldr: - new VC-backed startups are forming MSOs to roll up independent practices - The pitch is physicians receive early liquidity from the roll up and are granted ESOP shares that can be used for retirement - Problem is the use of ESOPs with independent practices is not a new concept and has been used with large group practices since the 70's - ESOPs do not grant full ownership and in order for the shares to be valuable for retirement, the practice needs to run the same if not better post roll up - With VC-backed startups being primarily operated by non-physicians with zero clinical or medical practice experience, the likelihood of this happening is extremely low making the entire concept high risk However, there is a viable path for continued ownership + liquidity for independent practices. Check out the article to learn more. ⤵ https://lnkd.in/gmGvTYwP

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For all of the differences between publicly traded and PE-owned companies, there are plenty of lessons that companies from each realm can learn from the other. Learn more in a new article by my colleagues Jordan Brugg and Colin Graham: https://lnkd.in/g3TggfhP #PrivateEquity #LeadershipMatters #SpencerStuartSiliconValleyandAustin

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There seems to be a misunderstanding on why/how AEC firms should acquire technology product companies. I have spent the last decade helping AEC firms figure this out. Foundational questions to be answered. - How do we monetize our innovation strategy? - How do we align innovation to provide a new product to existing markets AND/OR does the acquisition open a new market where we can provide our existing services? - Do we have the right culture to work with a team that is likely counter culture? - Do we know how to provide financial governance to a business model that we have no experience with? These are just a few.

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🔍 AI Fuels Optimism in San Francisco’s Office Market Recent data reveals that AI companies are significantly impacting San Francisco's office market: - 25% of all leasing activity in San Francisco since 2023 is driven by AI tenants. - AI firms are leading the market in net positive demand, one of the few sectors expanding their footprint. - Paramount Group noted “clear signs” of increased demand, largely due to AI companies prioritizing in-person collaboration. - Hudson Pacific Properties reported improvements across West Coast markets, with San Francisco showing the most promise. Crime is down, transit ridership is up, and sublease availability is declining. San Francisco’s office market, once struggling, is seeing a resurgence thanks to the rapid growth of AI, making this sector a key player in the city’s commercial real estate future. https://lnkd.in/gpqXWZwM

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There’s no one-size-fits-all approach to scaling a business, but the key is making intentional decisions about how you choose to grow. 🥾 Bootstrapping gives you control but might mean slower growth 🏦 Venture capital fuels fast growth but comes with trade-offs 🔋 A hybrid approach can balance both—but it requires discipline. At York IE, we believe that your growth strategy should reflect your goals, values, and market reality. Don’t chase hypergrowth for the sake of it. Be pragmatic, preserve optionality, and stay in control of your company’s fate.

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Increased competition in the AI landscape is a catalyst for innovation and improved user experiences. The pursuit of excellence is fueled by healthy rivalry, driving companies to refine their offerings and exceed expectations. As the saying goes, "A rising tide lifts all boats." In this dynamic environment, we all benefit from the collective push toward a brighter, more intelligent future.

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If you start down the path of #enterpriseimaging – which many health systems are doing (or considering) – "there have to be some objectives and a clear understanding of what you're attempting to do," said Joseph Marion during a recent discussion with Alex Towbin and Lenny Reznik. What you don't want is to go into it with "a false expectation or limited expectation." https://lnkd.in/gg3PkCim AGFA HealthCare #itimaging #healthcareit #enterpriseimagemanagement #patientsafety #patientexperience

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Thoughtful exploration of how GenAI will impact DevOps teams and their practices!

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Some VC investors believe that brick and mortar - referring to a physical presence of some kind - should be avoided at all costs. Yet, the track record of clinic and hybrid care businesses in health care indicates otherwise. ==> One Medical (sold for $3.9 billion to Amazon), Oak Street (bought by CVS for $10.6 billion), Lifestance (IPO at $7.5 billion market cap), and PE-backed Premise Health (acquired by OMERS Private Equity for $1.1 billion) If a clinic is indicated as the optimal way to deliver care for that patient population, there are creative ways to build and operate them. Full article below with advice and strategies on how to build and operate hybrid clinics from my teammate Anarghya Vardhana from Maveron, Amir Dan Rubin from OneMedical Group, Steven Eidelman from Modern Animal and more!

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As I said right at the start of this week's The Heart of Healthcare Podcast, Shivdev Rao is one of the most exceptional founders I have ever worked with. He is also a great human being. In this week's episode he shares what is it like leading the 🚀 that is Abridge and some awesome life lessons. IMHO this is a great listen for founders building in both the AI and healthcare fields!

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"More than $12.5 billion has been bet on digital behavioral health in the last five years, according to Rock Health. Funding peaked in 2021, with $5.7 billion spent that year alone." As investors and innovators, I believe we need to broaden our focus in the behavioral health space from just expanding access to care, to effectively measuring the quality of that care. As we continue to encourage individuals, employers and plans to increase their spending and focus on behavioral health, we need reliable tools for measuring the long-term efficacy and impact of behavioral health services.

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