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270 pages, Paperback
First published May 16, 2013
The perfect test or scan may have been available, but the physicians never ordered it.As you may be able to tell, I don't have the best relationship with the health industry. I have enough separate things wrong with me to necessitate regular visits to one or more institutions, but ever since a youth filled with borderline Munchausen By Proxy experiences and my undergrad days when my collegial institution would only give me treatment if I agreed to being experimented on by students, I don't do more than is absolutely necessary. Successive years of being in a community with my fellow neuroatypicals has given me plenty of stories of forced institutionalization, fat-shaming, racism, transphobia, and general abuse that was often only marginally lessened by rigorous research on the patient's side. I didn't expect Gawande to be all doom and gloom, but there was a pattern of pointing out fat patients as particularly difficult to operate on that wasn't much alleviated by a later article that all but swore by gastric bypass surgery. I could go into experiments that found rats became drug addicts when not offered enough positive stimulation and generally good environments, the all but 100% monetization of public spheres, the nearly ubiquitous inhumane conditions of workplaces that refuse all semblance of a healthy amount of sitting, standing, and general movement, but I won't. All I'll say is, there are a number of times when my teeth cleaner, aware of my pretty optimal dental status and less than optimal financial means, has offered to let me skip the MD's visit and spend half what I would have otherwise, and I can't think of a time when I refused the offer. So, that perfect scan or test? Doesn't mean jack squat if it's a choice between that and rent.
She was in what physicians call the "prodomal phase of emesis." Salivation increases, sometimes torrentially. The pupils dilate. The heart begins to race. The blood vessels in the skin constrict, increasing pallor..
While all this is going on, the stomach develops abnormal electrical activity, which prevents it from emptying and causes it to relax. The esaphagus contracts, pulling the upper portion of the stomach from the abdomen, through the diaphragm, and into the chest...Then, in a single movement, known as the "retrograde giant contraction," the upper small intestine evacuates its contents backward into the stomach in preparation for vomiting...In the expulsive phase, the diaphragm and stomach undergo a massive, prolonged contraction, generating intense pressure in the stomach; when the esophogus relaxes, it's as if someone had taken the plug off a fire hydrant.
"[...]studies show that even highly experienced surgeons inflict this terrible injury [cutting the main bile duct] about once in every two hundred lap choles. [...] a statistician would say that, no matter how hard I tried, I was almost certain to make this error at least once in the course of my career."One of the most fascinating fragments of the book deals with the human inability to choose the right decision when randomness and catastrophic results need to be considered. Suppose (this is my example) a patient has a condition that severely imperils the quality of life. Suppose there exists an operation, with a recorded success rate of 99%. But in the remaining 1% of cases the patient will die during the operation. We do know the probabilities but how can we estimate the numerical value of the patient's life relative to the value of their life with the debilitating condition and relative to the value of the healthy life? If we could, the mathematical problem would be simple but, of course, we can't! The additional complication is the natural human inability to understand the difference between probabilities of, say, 0.001 and 0.00001 of something very bad happening. Both events are unlikely to happen, but don't forget that both will eventually happen. To someone, maybe even us.
"How often do autopsies turn up a major misdiagnosis in the cause of death? I would have guessed this happens rarely, in 1 or 2 percent of cases at most. According to three studies done in 1998 and 1999, however, the figure is about 40%."So is medicine doomed to fail in a high percentage of cases? Or is there a chance for the medical success statistic to improve? The author's answer is positive and he repeatedly offers his suggestion of the best medication for the ailing medicine. In the last chapter he writes:
"[...] to shrink the amount of uncertainty in medicine -- with research, not on new drugs or operations (which already attracts massive amounts of funding) but on the small but critical everyday decisions that patients and doctors (which get shockingly little funding)."Reduction of uncertainty is the crucial step. It could be achieved by following the quality assurance guidelines from other fields of science and technology. Dr. Gawande mentions various methods and processes that are used to improve aviation safety as recommendations that could easily be adapted for the medical field; I would add the engineering disciplines in general, including software engineering and systems engineering. Standardization, uniformization, "routinization" of medicine are strongly recommended.