Talk:Fixation index: Difference between revisions

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I'm trying to reproduce the FST results from the Hapmap 3 paper (The International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature 449, 851-861. 2007) and they don't seem to be using the formula provided here. I believe they're using θ as defined by Reynolds, Weir, and Cockerham [Reynolds, John, Weir, B., S., Cockerham, C. Clark, ESTIMATION OF THE COANCESTRY COEFFICIENT: BASIS FOR A SHORT-TERM GENETIC DISTANCE, Genetics 1983 105: 767-779] which is also somewhat complicated. Perhaps this page should just include a simple FST formula, such as would be found in a standard population genetics textbook. —Preceding unsigned comment added by 192.12.88.17 (talk) 00:31, 17 October 2010 (UTC)[reply]

This article notes that "Across the autosomes, FST was estimated to be 0.12." but it would be nice to know what this means: Is that large, or small? —Preceding unsigned comment added by Tim bates (talk • contribs) 11:43, 3 June 2008 (UTC)[reply]

The 0.12 is a high value and represent populations of high variations (Asian and African origin HapMap populstions). The lowest range in the same HapMAp paper was 0.07. Dr. Rehab Abdel-Rahman —Preceding unsigned comment added by 71.242.172.165 (talk) 03:08, 29 June 2008 (UTC)[reply]