[HTML][HTML] fagin: synteny-based phylostratigraphy and finer classification of young genes
Background With every new genome that is sequenced, thousands of species-specific
genes (orphans) are found, some originating from ultra-rapid mutations of existing genes,
many others originating de novo from non-genic regions of the genome. If some of these
genes survive across speciations, then extant organisms will contain a patchwork of genes
whose ancestors first appeared at different times. Standard phylostratigraphy, the technique
of partitioning genes by their age, is based solely on protein similarity algorithms. However�…
genes (orphans) are found, some originating from ultra-rapid mutations of existing genes,
many others originating de novo from non-genic regions of the genome. If some of these
genes survive across speciations, then extant organisms will contain a patchwork of genes
whose ancestors first appeared at different times. Standard phylostratigraphy, the technique
of partitioning genes by their age, is based solely on protein similarity algorithms. However�…
[PDF][PDF] fagin: synteny-based phylostratigraphy and finer classification of young genes
Background: With every new genome that is sequenced, thousands of species-specific
genes (orphans) are found, some originating from ultra-rapid mutations of existing genes,
many others originating de novo from non-genic regions of the genome. If some of these
genes survive across speciations, then extant organisms will contain a patchwork of genes
whose ancestors first appeared at different times. Standard phylostratigraphy, the technique
of partitioning genes by their age, is based solely on protein similarity algorithms. However�…
genes (orphans) are found, some originating from ultra-rapid mutations of existing genes,
many others originating de novo from non-genic regions of the genome. If some of these
genes survive across speciations, then extant organisms will contain a patchwork of genes
whose ancestors first appeared at different times. Standard phylostratigraphy, the technique
of partitioning genes by their age, is based solely on protein similarity algorithms. However�…
Showing the best results for this search. See all results