[HTML][HTML] A deep neural network improves endoscopic detection of early gastric cancer without blind spots

…, A Yin, X Huang, J Liu, X Jiang, Z Wang, Y Deng…�- …, 2019 - thieme-connect.com
Background Gastric cancer is the third most lethal malignancy worldwide. A novel deep
convolution neural network (DCNN) to perform visual tasks has been recently developed. The …

[HTML][HTML] Fusobacterium nucleatum promotes metastasis in colorectal cancer by activating autophagy signaling via the upregulation of CARD3 expression

Y Chen, Y Chen, J Zhang, P Cao, W Su, Y Deng…�- Theranostics, 2020 - ncbi.nlm.nih.gov
Aims: We aimed to measure the abundance of Fusobacterium nucleatum (F. nucleatum) in
colorectal cancer (CRC) tissues from patients and to uncover the function of this bacterium in …

Effect of a deep learning-based system on the miss rate of gastric neoplasms during upper gastrointestinal endoscopy: a single-centre, tandem, randomised controlled�…

…, Z Zeng, Y Yu, C He, Q Xiong, Y Li, Y Deng…�- The Lancet�…, 2021 - thelancet.com
Background White light endoscopy is a pivotal first-line tool for the detection of gastric
neoplasms. However, gastric neoplasms can be missed during upper gastrointestinal endoscopy …

[HTML][HTML] Calmodulin 2 Facilitates Angiogenesis and Metastasis of Gastric Cancer via STAT3/HIF-1A/VEGF-A Mediated Macrophage Polarization

G Mu, Y Zhu, Z Dong, L Shi, Y Deng, H Li�- Frontiers in Oncology, 2021 - frontiersin.org
Background Tumor-associated macrophages (TAMs) are indispensable to mediating the
connections between cells in the tumor microenvironment. In this study, we intended to …

[HTML][HTML] SSRP1 contributes to the malignancy of hepatocellular carcinoma and is negatively regulated by miR-497

Q Ding, K He, T Luo, Y Deng, H Wang, H Liu, J Zhang…�- Molecular Therapy, 2016 - cell.com
The aim of this study is to clarify the clinical implication and functional role of structure
specific recognition protein 1 (SSRP1) in hepatocellular carcinoma (HCC) and explore the …

[HTML][HTML] Explainable artificial intelligence incorporated with domain knowledge diagnosing early gastric neoplasms under white light endoscopy

Z Dong, J Wang, Y Li, Y Deng, W Zhou, X Zeng…�- NPJ Digital�…, 2023 - nature.com
White light endoscopy is the most pivotal tool for detecting early gastric neoplasms. Previous
artificial intelligence (AI) systems were primarily unexplainable, affecting their clinical …

SSRP1 promotes colorectal cancer progression and is negatively regulated by miR‐28‐5p

…, K Huang, D Yang, L Wu, Y Deng…�- Journal of cellular�…, 2019 - Wiley Online Library
In this study, microarray data analysis, real‐time quantitative PCR and immunohistochemistry
were used to detect the expression levels of SSRP1 in colorectal cancer (CRC) tissue and …

[HTML][HTML] Multi-step validation of a deep learning-based system for the quantification of bowel preparation: a prospective, observational study

…, M Guo, X Zhang, Q Zhu, L Wu, Y Deng…�- The Lancet Digital�…, 2021 - thelancet.com
Background Inadequate bowel preparation is associated with a decrease in adenoma detection
rate (ADR). A deep learning-based bowel preparation assessment system based on the …

[HTML][HTML] miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling

…, L Yao, W Zhou, J Tian, B Ruan, Z Lu, Y Deng…�- …�Therapy-Nucleic Acids, 2021 - cell.com
Gastric cancer (GC) is one of the leading causes of cancer-related death worldwide. MicroRNAs
(miRNAs) are known to be important regulators of GC. This study aims to investigate the …

[HTML][HTML] A deep learning and natural language processing-based system for automatic identification and surveillance of high-risk patients undergoing upper�…

…, Z Dong, J Pan, Y Ai, J Liu, W Zhou, Y Deng…�- …, 2022 - thelancet.com
Background Timely identification and regular surveillance of patients at high risk are crucial
for early diagnosis of upper gastrointestinal cancer. However, traditional manual …