[HTML][HTML] Biogenesis, functions and clinical significance of circRNAs in gastric cancer

C Shan, Y Zhang, X Hao, J Gao, X Chen, K Wang�- Molecular cancer, 2019 - Springer
Gastric cancer (GC) is one of the most common malignant tumours in the world and has
high morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with …

Self-assembled organic nanomaterials for drug delivery, bioimaging, and cancer therapy

Y Zhang, F Fang, L Li, J Zhang�- ACS Biomaterials Science &�…, 2020 - ACS Publications
Over the past few decades, tremendous progress has been made in the development of
engineering nanomaterials, which opened new horizons in the field of diagnosis and treatment …

Protein chemical synthesis by serine and threonine ligation

Y Zhang, C Xu, HY Lam, CL Lee…�- Proceedings of the�…, 2013 - National Acad Sciences
An efficient method has been developed for the salicylaldehyde ester-mediated ligation of
unprotected peptides at serine (Ser) or threonine (Thr) residues. The utility of this peptide …

Methods for the detection of reactive oxygen species

Y Zhang, M Dai, Z Yuan�- Analytical Methods, 2018 - pubs.rsc.org
There are many pieces of evidence suggesting the mediating role of reactive oxygen species
(ROS) in cell life, stress and death, and it is known that ROS at different concentrations …

Tunable magnetic and microwave absorption properties of Sm1. 5Y0. 5Fe17-xSix and their composites

W Yang, Y Zhang, G Qiao, Y Lai, S Liu, C Wang, J Han…�- Acta Materialia, 2018 - Elsevier
In this work, we report the magnetic and microwave absorption properties of the Sm 1.5 Y 0.5
Fe 17-x Si x (0.0 ≤ x ≤ 1.5) and their paraffin composites. It was found that the introduction …

A review of sources, multimedia distribution and health risks of novel fluorinated alternatives

Y Wang, W Chang, L Wang, Y Zhang, Y Zhang…�- Ecotoxicology and�…, 2019 - Elsevier
Per- and polyfluoroalkyl substances (PFASs) are a class of emerging persistent organic
pollutants (POPs). They are widely used in industrial and consumer applications. Due to their …

The Paf1 complex is required for efficient transcription elongation by RNA polymerase I

Y Zhang, ML Sikes, AL Beyer…�- Proceedings of the�…, 2009 - National Acad Sciences
Regulation of RNA polymerase I (Pol I) transcription is critical for controlling ribosome
synthesis. Most previous investigations into Pol I transcription regulation have focused on …

Free radical as a double-edged sword in disease: Deriving strategic opportunities for nanotherapeutics

…, Y Zhang, F Fang, M Li, F An, D Zhao, J Zhang�- Coordination chemistry�…, 2023 - Elsevier
Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

Salicylaldehyde ester-induced chemoselective peptide ligations: enabling generation of natural peptidic linkages at the serine/threonine sites

X Li, HY Lam, Y Zhang, CK Chan�- Organic Letters, 2010 - ACS Publications
A serine/threonine-based chemoselective ligation method is described. It uses an O-salicylaldehyde
ester at the C-terminus, reacting with N-terminal serine or threonine to realize …

[HTML][HTML] Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized�…

…, CW Hendrix, SH Eshleman, Y Zhang…�- PLoS�…, 2018 - journals.plos.org
Background Cabotegravir (CAB) is a novel strand-transfer integrase inhibitor being developed
for HIV treatment and prevention. CAB is formulated both as an immediate-release oral …