Construction of a human cell landscape at single-cell level

…, H Tang, W Ge, Y Zhou, F Ye, M Jiang, J Wu, Y Xiao…�- Nature, 2020 - nature.com
Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems
1 . However, a comprehensive single-cell atlas has not been achieved for humans. Here …

Effect of vitamin D supplementation on some inflammatory biomarkers in type 2 diabetes mellitus subjects: a systematic review and meta-analysis of randomized�…

Y Yu, L Tian, Y Xiao, G Huang, M Zhang�- Annals of nutrition and�…, 2018 - karger.com
Background/Aims: The mechanism, by which vitamin D influences inflammatory biomarkers
in type 2 diabetes mellitus (T2DM), is not very well known. Thus, a meta-analysis of …

The preparation of silybin–phospholipid complex and the study on its pharmacokinetics in rats

X Yanyu, S Yunmei, C Zhipeng, P Qineng�- International journal of�…, 2006 - Elsevier
The aim of the present study was to find a way of prepare silybin–phospholipid complex to
make oral bioavailability of silybin increase and to study its physicochemical properties and to …

[HTML][HTML] An analytical framework for decoding cell type-specific genetic variation of gene regulation

Y Xiao, J Wang, J Li, P Zhang, J Li, Y Zhou…�- Nature�…, 2023 - nature.com
A deeper understanding of genetic regulation and functional mechanisms underlying genetic
associations with complex traits and diseases is impeded by cellular heterogeneity and …

[HTML][HTML] Recent advances in diverse nanosystems for nitric oxide delivery in cancer therapy

…, R Hu, S Chen, R Niu, J Liu, Z Chen, Y Xiao�- …�Pharmaceutica Sinica B, 2023 - Elsevier
Gas therapy has been proven to be a promising and advantageous treatment option for
cancers. Studies have shown that nitric oxide (NO) is one of the smallest structurally significant …

[HTML][HTML] Advanced nanomedicine for rheumatoid arthritis treatment: focus on active targeting

M Chen, KA Daddy JC, Y Xiao, Q Ping…�- Expert opinion on drug�…, 2017 - Taylor & Francis
Rheumatoid arthritis (RA) is characterized by synovial inflammation and hyperplasia,
autoantibody production, cartilage and bone destruction, and systemic features including …

Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas

…, J Wang, J Wu, T Wei, Q Chen, J Wu, C Yu, Y Xiao…�- Gut, 2019 - gut.bmj.com
Objective Hepatocellular carcinoma (HCC) is heterogeneous, especially in multifocal tumours,
which decreases the efficacy of clinical treatments. Understanding tumour heterogeneity …

Construction of a cross-species cell landscape at single-cell level

…, Y Mei, Z Sun, C Yu, J Shao, Y Fu, Y Xiao…�- Nucleic acids�…, 2023 - academic.oup.com
Individual cells are basic units of life. Despite extensive efforts to characterize the cellular
heterogeneity of different organisms, cross-species comparisons of landscape dynamics have …

Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery

J Shen, Y Wang, Q Ping, Y Xiao, X Huang�- Journal of controlled release, 2009 - Elsevier
This study was to develop a thiolated non-ionic surfactant, cysteine-polyethylene glycol
stearate (Cys-PEG-SA), for the assembling of nanoparticulate ocular drug delivery system with …

Preparation of silymarin proliposome: a new way to increase oral bioavailability of silymarin in beagle dogs

X Yan-yu, S Yun-mei, C Zhi-peng, P Qi-neng�- International journal of�…, 2006 - Elsevier
The aim of the present study was to find a method to increase oral bioavailability of silymarin,
that is to say, by the preparation of silymarin proliposome and to compare the …