User profiles for Stephan Frank

Stephan Frank

Basel University
Verified email at usb.ch
Cited by 20632

[HTML][HTML] The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

S Frank, B Gaume, ES Bergmann-Leitner, WW Leitner…�- Developmental cell, 2001 - cell.com
In healthy cells, fusion and fission events participate in regulating mitochondrial morphology.
Disintegration of the mitochondrial reticulum into multiple punctiform organelles during …

DNA methylation-based classification of central nervous system tumours

…, J Cryan, M Farrell, M Deckert, J Hench, S Frank…�- Nature, 2018 - nature.com
Accurate pathological diagnosis is crucial for optimal management of patients with cancer.
For the approximately 100 known tumour types of the central nervous system, standardization …

Transmission and spreading of tauopathy in transgenic mouse brain

…, T Bolmont, RA Crowther, D Abramowski, S Frank…�- Nature cell�…, 2009 - nature.com
Hyperphosphorylated tau makes up the filamentous intracellular inclusions of several
neurodegenerative diseases, including Alzheimer's disease 1 . In the disease process, neuronal …

[HTML][HTML] New brain tumor entities emerge from molecular classification of CNS-PNETs

…, U Sch�ller, M Ebinger, J Schittenhelm, S Frank…�- Cell, 2016 - cell.com
Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly
aggressive, poorly differentiated embryonal tumors occurring predominantly in young children …

Postmortem examination of COVID‐19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs�…

…, S Savic, H Hopfer, N Deigendesch, S Frank…�- …, 2020 - Wiley Online Library
Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2), has rapidly evolved into a sweeping pandemic. Its major …

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

…, YJ Lee, B Gaume, SY Jeong, S Frank…�- The Journal of cell�…, 2002 - rupress.org
We find that Bax, a proapoptotic member of the Bcl-2 family, translocates to discrete foci on
mitochondria during the initial stages of apoptosis, which subsequently become …

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

…, G Fraser, RA Crowther, S Frank…�- Proceedings of the�…, 2013 - National Acad Sciences
Filamentous inclusions made of hyperphosphorylated tau are characteristic of numerous
human neurodegenerative diseases, including Alzheimer’s disease, tangle-only dementia, Pick …

Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of�…

…, MM Siqueira, J Skręt-Magierło, F Stephan…�- The lancet Respiratory�…, 2014 - thelancet.com
Background Neuraminidase inhibitors were widely used during the 2009–10 influenza A H1N1
pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a …

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes

…, V Bonifati, K Gerwert, B Bohrmann, S Frank…�- Nature�…, 2019 - nature.com
Parkinson’s disease, the most common age-related movement disorder, is a progressive
neurodegenerative disease with unclear etiology. Key neuropathological hallmarks are Lewy …

The sloan digital sky survey-II supernova survey: technical summary

…, AV Filippenko, RJ Foley, S Frank…�- The Astronomical�…, 2007 - iopscience.iop.org
The Sloan Digital Sky Survey-II (SDSS-II) has embarked on a multi-year project to identify and
measure light curves for intermediate-redshift (0.05< z< 0.35) Type Ia supernovae (SNe Ia…