In photovoltaic systems, dc-dc converters have been identified as one of the most critical and challenging subsystem in terms of failure rate. Thus, this paper proposes fault-tolerant operation of a two-stage buck/buck-boost converter under open-circuit switch failure. Remedial actions are efficient in any failure of one of the two switches of the converter. Here, a new unified approach is considered, for the overall fault-tolerant operation of the two stages of the converter. The fault-tolerant circuit we propose lies on performing redundancy by implementing the equivalent synchronous switch for the two main switches of the two stages, in offline mode. The fault-tolerant circuit results from the basic two-stage buck/buck-boost converter and its equivalent circuit with a synchronous switch, merged together to form the new dc-dc fault-tolerant circuit. Therefore, postfault operation at full power can also be performed. By using a switch fault management unit with reduced complexity, inserted between the control block and the switches, we have designed an unified, efficient, and optimized fault-tolerant control, suitable in both healthy and postfault operations. Some selected experimental tests, which all confirm the good performances of the proposed fault-tolerant approach, are presented and discussed.