High serum IgG4 concentrations in patients with sclerosing pancreatitis

…, T Nikaido, K Nakayama, N Usuda…�- …�England Journal of�…, 2001 - Mass Medical Soc
Background Sclerosing pancreatitis is a unique form of pancreatitis that is characterized by
irregular narrowing of the main pancreatic duct, lymphoplasmacytic inflammation of the …

The lipid droplet is an important organelle for hepatitis C virus production

Y Miyanari, K Atsuzawa, N Usuda, K Watashi…�- Nature cell�…, 2007 - nature.com
The lipid droplet (LD) is an organelle that is used for the storage of neutral lipids. It
dynamically moves through the cytoplasm, interacting with other organelles, including the …

[HTML][HTML] Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase: implications for peroxisome�…

CY Fan, J Pan, N Usuda, AV Yeldandi, MS Rao…�- Journal of Biological�…, 1998 - ASBMB
Peroxisomal β-oxidation system consists of four consecutive reactions to preferentially
metabolize very long chain fatty acids. The first step of this system, catalyzed by acyl-CoA oxidase …

[HTML][HTML] Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene

…, J Pan, R Chu, D Lee, KD Kluckman, N Usuda…�- Journal of Biological�…, 1996 - ASBMB
Peroxisomal genetic disorders, such as Zellweger syndrome, are characterized by defects in
one or more enzymes involved in the peroxisomal β-oxidation of very long chain fatty acids …

[HTML][HTML] Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation*♦

…, M Nomura, T Yanase, K Otsu, N Usuda…�- Journal of Biological�…, 2012 - ASBMB
Lipid droplets (LDs) are ubiquitous organelles storing neutral lipids, including triacylglycerol
(TAG) and cholesterol ester. The properties of LDs vary greatly among tissues, and LD-…

[HTML][HTML] Peroxisomal and mitochondrial fatty acid β-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor α and peroxisomal fatty acyl-CoA�…

T Hashimoto, T Fujita, N Usuda, W Cook, C Qi…�- Journal of Biological�…, 1999 - ASBMB
Fatty acid β-oxidation occurs in both mitochondria and peroxisomes. Long chain fatty acids
are also metabolized by the cytochrome P450 CYP4A ω-oxidation enzymes to toxic …

[HTML][HTML] Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral�…

…, N Hayashi, H Suzuki, M Higuchi, N Usuda…�- …, 2013 - nature.com
Schnurri-2 (Shn-2), an nuclear factor-κB site-binding protein, tightly binds to the enhancers
of major histocompatibility complex class I genes and inflammatory cytokines, which have …

Activation of JAK/STAT signalling in neurons following spinal cord injury in mice

…, K Osuka, M Takayasu, N Usuda…�- Journal of�…, 2006 - Wiley Online Library
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signalling
pathway is one of the most important in transducing signals from the cell surface to the nucleus …

Presence of molecular chaperones, heat shock cognate (Hsc) 70 and heat shock proteins (Hsp) 40, in the postsynaptic structures of rat brain

T Suzuki, N Usuda, S Murata, A Nakazawa, K Ohtsuka…�- Brain research, 1999 - Elsevier
The synaptic localization of molecular chaperones, heat shock cognate protein 70 (Hsc70)
and Hsp40, was investigated immunohistochemically in the normal rat brain. Postsynaptic …

Localization of elastin in the normal and glaucomatous human trabecular meshwork.

…, M Nohara, T Hanai, N Usuda…�- …�& visual science, 1994 - iovs.arvojournals.org
PURPOSE: The extracellular materials (ECMs) in the trabecular meshwork (TM) are thought
to play a crucial role in aqueous outflow resistance. Immunohistochemical localization of …