Nucleotide sequences of 50 human Alu repeats and their flanking regions are presented
together with the consensus sequence based on the literature and our findings. The results …

Purpose: Examination of somatic epidermal growth factor receptor (EGFR) mutations is now
a diagnostic routine for treatment of cancer using EGFR tyrosine kinase inhibitors (EGFR-TKI…

Huntington’s disease (HD) is one of 10 known diseases caused by a (CAG) n trinucleotide
repeat expansion that is translated into an abnormally long polyglutamine tract. We have …

Somatic mutations introduced into the epidermal growth factor receptor (EGFR) gene in non‐small‐cell
lung cancer (NSCLC) are important factors to determine therapeutic responses to …

Purpose Docetaxel is one of the most effective anticancer drugs available in the treatment of
breast cancer. Nearly half of the treated patients, however, do not respond to chemotherapy …

Drug resistance acquired by cancer cells has led to treatment failure. To understand the
regulatory network underlying docetaxel resistance in breast cancer cells and to identify …

Purpose: Thioredoxin overexpression is suggested to be associated with resistance to several
chemotherapeutic agents in vitro. In the present study, it has been studied whether or not …

GABA (γ-aminobutyric acid), the major inhibitory neurotransmitter in the vertebrate brain,
mediates neuronal inhibition by opening a chloride channel integral to the GABA A receptor. …

Circulating tumour DNA (ctDNA) is an emerging field of cancer research. However, current
ctDNA analysis is usually restricted to one or a few mutation sites due to technical limitations. …

A synthetic DNA based on the known amino acid sequence of the brain/gut peptide
cholecystokinin (CCK) was synthesized. This DNA contained deoxyinosines at ambiguous codon …