pH/H2O2 Dual-Responsive Chiral Mesoporous Silica Nanorods Coated with a Biocompatible Active Targeting Ligand for Cancer Therapy

…, K Gou, W Kang, X Guo, K Zhu, S Li, H Li�- …�Applied Materials &�…, 2021 - ACS Publications
Nano-drug delivery systems (nano-DDSs) with an existing specific interaction to tumor cells
and intelligent stimulus-triggered drug delivery performance in a tumor microenvironment (…

Evaluation of biomimetically synthesized mesoporous silica nanoparticles as drug carriers: structure, wettability, degradation, biocompatibility and brain distribution

H Li, X Wu, B Yang, J Li, L Xu, H Liu, S Li, J Xu…�- Materials Science and�…, 2019 - Elsevier
Herein, three kinds of mesoporous silica nanoparticles (BMSs) were biomimetically synthesized
by using heterocyclic amino acid derivatives as template and their the basic capacity in …

Chiral nanosilica drug delivery systems stereoselectively interacted with the intestinal mucosa to improve the oral adsorption of insoluble drugs

…, L Wu, X Hao, Z Bao, X Li, M Yang, Q Luo, H Li�- ACS�…, 2023 - ACS Publications
Chiral nanoparticles (NPs) with nanoscale rough surfaces have enormous application prospects
in drug delivery. However, the stereoselective interactions between the chiral NPs and …

Biomimetic synthesis and evaluation of histidine-derivative templated chiral mesoporous silica for improved oral delivery of the poorly water-soluble drug, nimodipine

H Li, H Li, C Wei, J Ke, J Li, L Xu, H Liu, S Li…�- European Journal of�…, 2018 - Elsevier
In this study, spherical shaped chiral mesoporous silica nanoparticles (CMS) was
biomimetic synthesized using histidine derivatives (C 16 -L-histidine) as template via the sol–gel …

Amino functionalized mesoporous silica with twisted rod-like shapes: Synthetic design, in vitro and in vivo evaluation for ibuprofen delivery

Y Wang, J Ke, K Gou, Y Guo, X Xu, S Li, H Li�- …�and Mesoporous Materials, 2020 - Elsevier
In the present study, amino functionalized mesoporous silica (Amino-MSR) with twisted rod-like
shapes was successfully fabricated using biomimetic method, and employed as poorly …

[HTML][HTML] Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery

Z Sang, L Xu, R Ding, M Wang, X Yang, X Li…�- Nature�…, 2023 - nature.com
The oral delivery of nano-drug delivery systems (Nano-DDS) remains a challenge. Taking
inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles (NPs, …

Self-powered difunctional sensors based on sliding contact-electrification and tribovoltaic effects for pneumatic monitoring and controlling

Y Shi, H Li, X Fu, R Luan, Y Wang, N Wang, Z Sun…�- Nano Energy, 2023 - Elsevier
Pneumatic elements such as position and velocity sensors play a vital role in pneumatic
monitoring and servo control, which have great demands for integration, multifunction and self-…

Kadsuralignans H−K from Kadsura coccinea and Their Nitric Oxide Production Inhibitory Effects

H Li, L Wang, Z Yang, S Kitanaka�- Journal of natural products, 2007 - ACS Publications
One new arylnaphthalene lignan named kadsuralignan H (1) and three new dibenzocyclooctadiene
lignans, named kadsuralignans I (2), J (3), and K (4), respectively, were isolated …

Synthesis, structural properties, biosafety and applications of chiral mesoporous silica nanostructures

…, L Xie, X Guo, Y Guo, J Ke, L Wu, S Li, H Li�- Chemical Engineering�…, 2021 - Elsevier
Chiral mesoporous silica nanoparticles (CMSNs) are important members of mesoporous silica
nanoparticles (MSNs) family. They not only exhibit prominent physicochemical properties …

[HTML][HTML] Chiral mesoporous silica nano-screws as an efficient biomimetic oral drug delivery platform through multiple topological mechanisms

…, K Gou, Z Sang, Y Wang, Y Bian, S Li, H Li�- …�Pharmaceutica Sinica B, 2022 - Elsevier
In the microscale, bacteria with helical body shapes have been reported to yield advantages
in many bio-processes. In the human society, there are also wisdoms in knowing how to …