User profiles for Evan Fletcher
Evan FletcherProject Scientist, Department of Neurology, UC Davis Verified email at ucdavis.edu Cited by 15174 |
White matter lesions impair frontal lobe function regardless of their location
Objective: To analyze the effect of white matter lesions in different brain regions on regional
cortical glucose metabolism, regional cortical atrophy, and cognitive function in a sample …
cortical glucose metabolism, regional cortical atrophy, and cognitive function in a sample …
Anatomical mapping of white matter hyperintensities (wmh) exploring the relationships between periventricular WMH, deep WMH, and total WMH burden
Background and Purpose— MRI segmentation and mapping techniques were used to
assess evidence in support of categorical distinctions between periventricular white matter …
assess evidence in support of categorical distinctions between periventricular white matter …
Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study
Background Previous studies have identified effects of age and vascular risk factors on
brain injury in elderly individuals. We aimed to establish whether the effects of high blood …
brain injury in elderly individuals. We aimed to establish whether the effects of high blood …
Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative
…, C Schwarz, D Drucker, E Fletcher…�- Archives of�…, 2010 - jamanetwork.com
Objective To evaluate relationships between magnetic resonance imaging (MRI)–based
measures of white matter hyperintensities (WMHs), measured at baseline and longitudinally, …
measures of white matter hyperintensities (WMHs), measured at baseline and longitudinally, …
Covariations in ERP and PET measures of spatial selective attention in human extrastriate visual cortex
…, JB Hopfinger, CL Kussmaul, EM Fletcher…�- Human brain�…, 1997 - Wiley Online Library
In a previous study using positron emission tomography (PET), we demonstrated that focused
attention to a location in the visual field produced increased regional cerebral blood flow …
attention to a location in the visual field produced increased regional cerebral blood flow …
Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals
E Fletcher, M Raman, P Huebner, A Liu…�- JAMA�…, 2013 - jamanetwork.com
Importance Magnetic resonance imaging markers of incipient cognitive decline among healthy
elderly individuals have become important for both clarifying the biological underpinnings …
elderly individuals have become important for both clarifying the biological underpinnings …
Brain volume change and cognitive trajectories in aging.
E Fletcher, B Gavett, D Harvey, ST Farias…�- …, 2018 - psycnet.apa.org
Objective: Examine how longitudinal cognitive trajectories relate to brain baseline measures
and change in lobar volumes in a racially/ethnically and cognitively diverse sample of older …
and change in lobar volumes in a racially/ethnically and cognitively diverse sample of older …
White matter changes compromise prefrontal cortex function in healthy elderly individuals
Abstract Changes in memory function in elderly individuals are often attributed to dysfunction
of the prefrontal cortex (PFC). One mechanism for this dysfunction may be disruption of …
of the prefrontal cortex (PFC). One mechanism for this dysfunction may be disruption of …
Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional–executive network function in Alzheimer's disease
…, J Felmlee, A Fleisher, E Fletcher…�- Proceedings of the�…, 2010 - National Acad Sciences
The ε4 allele of the apolipoprotein E (APOE) gene is the major genetic risk factor for
Alzheimer’s disease (AD), but limited work has suggested that APOE genotype may modulate …
Alzheimer’s disease (AD), but limited work has suggested that APOE genotype may modulate …
White matter hyperintensity penumbra
Background and Purpose— White matter hyperintensities (WMHs) are associated with
progressive age-related cognitive decline and cardiovascular risk factors, but their biological …
progressive age-related cognitive decline and cardiovascular risk factors, but their biological …