In the realm of network science, many topics can be abstracted as graph problems, such as routing, connectivity enhancement, resource/frequency allocation and so on. Though most of them are NP-hard to solve, heuristics as well as approximation algorithms are proposed to achieve reasonably good results. Accordingly, this dissertation studies graph related problems encountered in real applications. Two problems studied in this dissertation are derived from wireless network, two more problems studied are under scenarios of FIWI and optical network, one more problem is in Radio-Frequency Identification (RFID) domain and the last problem is inspired by satellite deployment.