Deep Survival Machines: Fully Parametric Survival Regression and Representation Learning for Censored Data With Competing Risks

C Nagpal, X Li, A Dubrawski�- IEEE Journal of Biomedical and�…, 2021 - ieeexplore.ieee.org
IEEE Journal of Biomedical and Health Informatics, 2021ieeexplore.ieee.org
We describe a new approach to estimating relative risks in time-to-event prediction problems
with censored data in a fully parametric manner. Our approach does not require making
strong assumptions of constant proportional hazards of the underlying survival distribution,
as required by the Cox-proportional hazard model. By jointly learning deep nonlinear
representations of the input covariates, we demonstrate the benefits of our approach when
used to estimate survival risks through extensive experimentation on multiple real world�…
We describe a new approach to estimating relative risks in time-to-event prediction problems with censored data in a fully parametric manner. Our approach does not require making strong assumptions of constant proportional hazards of the underlying survival distribution, as required by the Cox-proportional hazard model. By jointly learning deep nonlinear representations of the input covariates, we demonstrate the benefits of our approach when used to estimate survival risks through extensive experimentation on multiple real world datasets with different levels of censoring. We further demonstrate advantages of our model in the competing risks scenario. To the best of our knowledge, this is the first work involving fully parametric estimation of survival times with competing risks in the presence of censoring.
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