Serum and tissue trace elements in patients with breast cancer in Taiwan

HW Kuo, SF Chen, CC Wu, DR Chen…�- Biological trace element�…, 2002 - Springer
The objective of this study was to compare levels of four elements (zinc, copper, selenium,
and iron) in the serum and tissue of 68 breast tumor patients (benign and malignant), from a …

Watershed segmentation for breast tumor in 2-D sonography

YL Huang, DR Chen�- Ultrasound in medicine & biology, 2004 - Elsevier
Automatic contouring for breast tumors using medical ultrasound (US) imaging may assist
physicians without relevant experience, in making correct diagnoses. This study integrates the …

Computer-aided diagnosis applied to US of solid breast nodules by using neural networks

DR Chen, RF Chang, YL Huang�- Radiology, 1999 - pubs.rsna.org
PURPOSE: To increase the capabilities of ultrasonographic (US) technology for the differential
diagnosis of solid breast tumors by using a neural network. MATERIALS AND METHODS: …

Diagnosis of breast tumors with sonographic texture analysis using wavelet transform and neural networks

DR Chen, RF Chang, WJ Kuo, MC Chen…�- Ultrasound in medicine &�…, 2002 - Elsevier
To increase the ability of ultrasonographic technology for the differential diagnosis of solid
breast tumors, we describe a novel computer-aided diagnosis (CADx) system using neural …

Breast cancer diagnosis using self-organizing map for sonography

DR Chen, RF Chang, YL Huang�- Ultrasound in medicine & biology, 2000 - Elsevier
The purpose of this study was to evaluate the performance of neural network model self-organizing
maps (SOM) in the classification of benign and malignant sonographic breast lesions…

Quercetin-mediated cell cycle arrest and apoptosis involving activation of a caspase cascade through the mitochondrial pathway in human breast cancer MCF-7 cells

…, JG Chung, MJ Chou, YH Teng, DR Chen�- Archives of pharmacal�…, 2010 - Springer
Dietary polyphenols have been correlated with a reduced risk of developing cancer. Quercetin
(a natural polyphenolic compound) induced apoptosis in many human cancer cell lines, …

Automatic ultrasound segmentation and morphology based diagnosis of solid breast tumors

RF Chang, WJ Wu, WK Moon, DR Chen�- Breast cancer research and�…, 2005 - Springer
Ultrasound (US) is a useful diagnostic tool to distinguish benign from malignant masses of
the breast. It is a very convenient and safe diagnostic method. However, there is a …

Classification of breast ultrasound images using fractal feature

DR Chen, RF Chang, CJ Chen, MF Ho, SJ Kuo…�- Clinical imaging, 2005 - Elsevier
Fractal analyses have been applied successfully for the image compression, texture analysis,
and texture image segmentation. The fractal dimension could be used to quantify the …

Quercetin-induced apoptosis acts through mitochondrial-and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells

…, WG Wood, SJ Kuo, DR Chen�- Human &�…, 2009 - journals.sagepub.com
There has been considerable evidence recently demonstrating the anti-tumour effects of
flavonols. Quercetin, an ubiquitous bioactive flavonol, inhibits cells proliferation, induces cell …

Support vector machines for diagnosis of breast tumors on US images

RF Chang, WJ Wu, WK Moon, YH Chou, DR Chen�- Academic radiology, 2003 - Elsevier
RATIONALE AND OBJECTIVES: Breast cancer has become the leading cause of cancer
deaths among women in developed countries. To decrease the related mortality, disease must …