User profiles for Barry Robson

Barry Robson

The Dirac Foundation, Ingine Inc., Prof. Emeritus St. Matthew's University
Verified email at ingine.com
Cited by 14706

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

J Garnier, DJ Osguthorpe, B Robson�- Journal of molecular biology, 1978 - Elsevier
(1) Co-operation between a laboratory interested in developing the theory for protein
secondary structure prediction methods and a laboratory interested in applying and comparing …

[32] GOR method for predicting protein secondary structure from amino acid sequence

J Garnier, JF Gibrat, B Robson�- Methods in enzymology, 1996 - Elsevier
Publisher Summary This chapter discusses the Garnier–Osguthorpe–Robson (GOR) method
for predicting protein secondary structure from amino acid sequence. The chapter presents …

Further developments of protein secondary structure prediction using information theory: new parameters and consideration of residue pairs

JF Gibrat, J Garnier, B Robson�- Journal of molecular biology, 1987 - Elsevier
We have re-evaluated the information used in the Garnier-Osguthorpe-Robson (GOR) method
of secondary structure prediction with the currently available database. The framework of …

An algorithm for secondary structure determination in proteins based on sequence similarity

JM Levin, B Robson, J Garnier�- FEBS letters, 1986 - Wiley Online Library
A secondary structure prediction algorithm is proposed on the hypothesis that short
homologous sequences of amino acids have the same secondary structure tendencies. …

What is a conservative substitution?

S French, B Robson�- Journal of molecular Evolution, 1983 - Springer
It is commonly recognised that many evolutionary changes of amino acid sequence in proteins
are conservative: a substitution of one amino acid residue for another has a far greater …

Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS�…

B Robson�- Computers in biology and medicine, 2020 - Elsevier
This paper concerns study of the genome of the Wuhan Seafood Market isolate believed to
represent the causative agent of the disease COVID-19. This is to find a short section or …

COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles' heel�…

B Robson�- Computers in biology and medicine, 2020 - Elsevier
This paper continues a recent study of the spike protein sequence of the COVID-19 virus (SARS-CoV-2).
It is also in part an introductory review to relevant computational techniques for …

Analysis of the code relating sequence to conformation in globular proteins. Theory and application of expected information

B Robson�- Biochemical Journal, 1974 - portlandpress.com
1. An information theory analysis of the folding of a globular protein is proposed. 2. The folding
is seen as a transfer of information between two messages, the primary sequence and the …

Data mining and clinical data repositories: Insights from a 667,000 patient data set

…, CT Garrett, WG Miller, R Muller, B Robson…�- Computers in biology�…, 2006 - Elsevier
Clinical repositories containing large amounts of biological, clinical, and administrative data
are increasingly becoming available as health care systems integrate patient information for …

Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans

B Robson�- Computers in biology and medicine, 2020 - Elsevier
SARS-CoV and SARS-CoV-2 do not appear to have functions of a hemagglutinin and
neuraminidase. This is a mystery, because sugar binding activities appear essential to many other …